Registration Dossier
Registration Dossier
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EC number: 915-761-2 | CAS number: -
Endpoint summary
Administrative data
Description of key information
The key values for Basic Red 046 Methyl Sulfate regarding aquatic toxicity were:
96-hour LC50 to fish = 29 mg/l,
48-hour EC50 to Daphnia = 1.5 mg/l,
7-day EC50 to Lemna = 27 mg/l,
7-day NOEC to Lemna = 1.7 mg/l and
21-day IC50 to bacterial organisms = 100 mg/l
Additional information
Basic Red 046 Methyl Sulfate was evaluated for toxicity to fish, Lemna and bacterial organisms. No study evaluating its toxicity to Daphnia are available. However, a structurally similar substance, Basic Red 046 Bromide (FAT 31016/P) was evaluated for assessment of toxicity to Daphnia, which was used for fulfilment of the endpoint requirement.
FAT 31016/F was evaluated for short term toxicity to rainbow trout in a study conducted using a methodology similar to OECD Guideline 203, where 96-hour LC50 was determined to be 29 mg/l.
FAT 31016/F was evaluated for short term toxicity to zebra fish in a study conducted using a methodology similar to OECD Guideline 203, where 96-hour LC50 was determined to be 46 mg/l.
The acute toxicity of FAT - 31'016/P to Daphnia magna was determined in a 48-hours static test according to the OECD Guideline 202, and EU method C.2, where the EC50 value was determined to be 1.5 mg/l, while the EC100 value was 3.3 mg/l after 48 hours.
In a study conducted according to OECD Guideline 221, the EC50 and NOEC based on growth rate (frond number) to Lemna, were determined to be 27 and 1.7 mg/l, respectively.
The 21-day IC50 to bacterial organisms for FAT 31016/F was determined to be 100 mg/l.
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