3,7-dimethylnon-6-en-1-yn-3-ol

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: well documented guideline study

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2000

Report date:

2000

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 203 (Fish, Acute Toxicity Test)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

3,7-dimethylnon-6-en-1-yn-3-ol

EC Number:

246-061-9

EC Name:

3,7-dimethylnon-6-en-1-yn-3-ol

Cas Number:

24173-47-5

Molecular formula:

C11H18O

IUPAC Name:

3,7-dimethylnon-6-en-1-yn-3-ol

Test organisms

Test organisms (species):

Cyprinus carpio

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96 h

Results and discussion

Effect concentrations

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

13 mg/L

Nominal / measured:

meas. (initial)

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Any other information on results incl. tables

Sublethal observations / clinical signs:

-

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

The 96h-LC50for carp exposed to ETHYLDEHYDROLINALOOL was 13 mg/I with 0% mortality
at 10 mg/I and 100% mortality at 18 mg/I. The 96h-LC50was already reached within 4 hours of exposure.

Executive summary:

The project started with a range-finding test exposing three fish per concentration to a concentration range of 0.1 to 100 mg/l with an increasing factor of 10. All fish exposed to 100 mg/l died within 3 hours of exposure. Fish exposed to 10 mg/l and lower survived the test period. After the range-finding test, a final test was performed with carp exposed to concentrations ranging from 10 to 100 mg/l in a static system. Seven carp were exposed per concentration and a control. Samples for analytical confirmation of actual exposure concentrations were taken at the start and the end of the test. Analysis of the samples was based on the two major peaks observed in the chromatograms from ETHYLDEHYDROLINALOOL, i.e. the components ETHYLDEHYDROLINALOOL-1 and ETHYLDEHYDROLINALOOL-2. Analysis of the samples taken during the final test showed that measured concentrations of both components were in agreement with nominal. ETHYLDEHYDROLINALOOL induced no lethal effects in carp at 10 mg/l. The 96h-LC 50 for carp exposed to ETHYLDEHYDROLINALOOL was 13 mg/l with 0% mortality at 10mg/l and 100% mortality at 18mg/l. The 96h-LC 50was already reached within 4 hours of exposure.