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Diss Factsheets
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EC number: 202-855-7 | CAS number: 100-47-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1988
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- Guideline study (OECD 301 E) with acceptable restrictions which do not impair the overall conclusion from the data; buffer used has a higher capacity than that described in OECD Guideline, incubation at 20+/-2°C instead of 22+/-2°C, no information about light conditions; information on purity of test substance is missing,but as ths substance is readily biodegradable potential impurities don't have a negative influence on the test result.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- Deviations:
- yes
- Remarks:
- incubation at 20+/-2°C instead of 22+/-2°C, no information about light conditions
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 12.2 mg/L
- Based on:
- test mat.
- Initial conc.:
- 24.3 mg/L
- Based on:
- test mat.
- Parameter:
- % degradation (DOC removal)
- Value:
- 0
- Sampling time:
- 0 d
- Remarks on result:
- other: 12.2 mg/l BN added
- Parameter:
- % degradation (DOC removal)
- Value:
- 100
- Sampling time:
- 14 d
- Remarks on result:
- other: 12.2 mg/l BN added
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 100
- Sampling time:
- 28 d
- Remarks on result:
- other: 12.2 mg/l BN added
- Parameter:
- % degradation (DOC removal)
- Value:
- 0
- Sampling time:
- 0 d
- Remarks on result:
- other: 24.3 mg/l BN added
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 100
- Sampling time:
- 14 d
- Remarks on result:
- other: 24.3 mg/l BN added
- Details on results:
- The results show a complete degradation of sodium acetate within one week as expected of an inoculum with sufficient activity. This degradation of sodium acetate was not influenced by the presence of benzonitrile in the medium.
A complete degradation of benzonitrile took place within 7 days.
12.2 mg/l BN added 24.3 mg/l BN added
Days mg DOC/l % mg DOC/l %
0 6 0 12 0
7 0 100 1 92
14 0 100 0 100
28 1 83 1 92 - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Benzonitrile is regarded as readily biodegradable.
- Executive summary:
The biodegradability of the product Benzonitrile was determined by the method laid down in the OECD Guideline 301E; 'Ready Biodegaradbility: Modified OECD Screening Test'.
Benzonitrile was tested in two concentrations: 12 mg/L and 24 mg/L. A control test with sodium acetate showed that the activity of the inoculum was sufficient, and that there was no inhibition of the inoculum activity by Benzonitrile.
Significant biodegradability was found in the test bottles with Benzonitrile; this substance is regarded as readily biodegradable.
Reference
Description of key information
Benzonitriles is regarded as readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
The biodegradability of the product Benzonitrile was determined by the method laid down in the OECD Guideline 301E; 'Ready Biodegaradbility: Modified OECD Screening Test'.
Benzonitrile was tested at two concentrations: 12 mg/L and 24 mg/L. A control test with sodium acetate showed that the activity of the inoculum was sufficient, and that there was no inhibition of the inoculum activity by Benzonitrile.
Significant biodegradability was found in the test bottles with Benzonitrile; this substance is regarded as readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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