Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name:
  • IUPAC name: tetrasodium 2-({4-fluoro-6-[methyl({2-[2-(sulfooxy)ethanesulfonyl]ethyl})amino]-1,3,5-triazin-2-yl}amino)-5-hydroxy-6-[2-(4-methyl-2-sulfophenyl)diazen-1-yl]naphthalene-1,7-disulfonate
  • Substance names and other identifiers
EC / List no.:
432-550-6
CAS no.:
243858-01-7
Index number:
Molecular formula:
C25H22FN7Na4O16S5
SMILES:
[Na+].[Na+].[Na+].[Na+].CN(CCS(=O)(=O)CCOS([O-])(=O)=O)C1=NC(NC2=CC=C3C(O)=C(N=NC4=CC=C(C)C=C4S([O-])(=O)=O)C(=CC3=C2S([O-])(=O)=O)S([O-])(=O)=O)=NC(F)=N1
InChI:
InChI=1S/C25H26FN7O16S5.4Na/c1-13-3-5-16(18(11-13)51(37,38)39)31-32-20-19(52(40,41)42)12-15-14(21(20)34)4-6-17(22(15)53(43,44)45)27-24-28-23(26)29-25(30-24)33(2)7-9-50(35,36)10-8-49-54(46,47)48;;;;/h3-6,11-12,34H,7-10H2,1-2H3,(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,27,28,29,30);;;;/q;4*+1/p-4
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
2
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
ELINCS (European LIst of Notified Chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance causes serious eye damage.

According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.

Breakdown of all 1 C&L notifications submitted to ECHA

Not Classified
Eye Dam. 1 H318 Harmonised Classification
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 1 active registrations under REACH, 1 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1+ tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

Other release to the environment of this substance is likely to occur from: indoor use.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used for the manufacture of: textile, leather or fur.

This substance is used in the following activities or processes at workplace: treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: indoor use.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: mixing in open batch processes, transfer of chemicals at dedicated facilities and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used for the manufacture of: textile, leather or fur.

This substance is used in the following activities or processes at workplace: transfer of chemicals, calendering operations, transfer of substance into small containers, roller or brushing applications and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: in the production of articles.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Immediately call a poison center or doctor/physician.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • DyStar Colours Distribution GmbH, Am Prime-Parc 12 65479 Raunheim Germany
  • CFB Chemische Fabrik Brunsbüttel GmbH, Kühlturmstrasse 06803 Bitterfeld-Wolfen / OT Greppin Germany

Substance names and other identifiers

REAKTIV-ORANGE F 97-0318
REACH pre-registration
Tetrasodium 2-(4-fluoro-6-(methyl-(2-(sulfatoethylsulfonyl)ethyl)amino)-1,3,5-triazin-2-ylamino)-5-hydroxy-6-(4-methyl-2-sulfonatophenylazo)naphthalene-1,7-disulfonate
C&L Inventory, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties
2-(4-fluor-6-(metil-(2-(sulfatoetilsulfonil)etil)amino)-1,3,5-triazin-2-ilamino)-5-hidroxi-6-(4-metil-2-sulfonatofenilazo)naftalen-1,7-disulfonat de tetrasodiu (ro)
C&L Inventory
2-(4-fluoro-6-(metil-(2-(solfatoetilsolfonil)etil)ammino)-1,3,5-triazin-2-ilammino)-5-idrossi-6-(4-metil-2-solfonatofenilazo)naftalene-1,7-disolfonato di tetrasodio (it)
C&L Inventory
2-(4-fluoro-6-(metil-(2-(sulfatoetilsulfonil)etil)amino)-1,3,5-triazin-2-ilamino)-5-hidroxi-6-(4-metil-2-sulfonatofenilazo)naftaleno-1,7-dissulfonato de tetrassódio (pt)
C&L Inventory
2-(4-fluoro-6-(metil-(2-(sulfatoetilsulfonil)etil)amino)-1,3,5-triazin-2-ilamino)-5-hidroxi-6-(4-metil-2-sulfonatofenilazo)naftaleno-1,7-disulfonato de tetrasodio (es)
C&L Inventory
2-(4-fluoro-6-(metylo-(2-(sulfatoetylosulfonylo)etylo)amino)-1,3,5-triazin-2-yloamino)-5-hydroksy-6-(4-metylo-2-sulfonatofenyloazo)naftaleno-1,7-disulfonian tetrasodu (pl)
C&L Inventory
2-(4-fluoro-6-(méthyl-(2-(sulfatoéthylsulfonyl)éthyl)amino)-1,3,5-triazin-2-ylamino)-5-hydroxy-6-(4-méthyl-2-sulfonatophénylazo)naphtalène-1,7-disulfonate de tétrasodium (fr)
C&L Inventory
2-(4-fluworo-6-(metil-(2-(sulfatetilsulfonil)etil)ammino)-1,3,5-triażin-2-ilammino)-5-idrossi-6-(4-metil-2-sulfonatofenilażo)naftalin-1,7-disulfonat tat-tetrasodju (mt)
C&L Inventory
2-(4-φθορο-6-(μεθυλο-(2-(θειικοαιθυλοσουλφονυλ)αιθυλ)αμινο)-1,3,5-τριαζιν-2-υλαμινo)-5-υδροξυ-6-(4-μεθυλο-2-σoυλφoνικοφαινυλαζω)ναφθαλινο-1,7-δισουλφονικό νάτριο (el)
C&L Inventory
tetranaatrium-2-(4-fluoro-6-(metüül-(2-(sulfatoetüülsulfonüül)etüül)amino)-1,3,5-triasiin-2-üülamino)-5-hüdroksü-6-(4-metüül-2-sulfonatofenüülaso)naftaleen-1,7-disulfonaat (et)
C&L Inventory
tetranatrijev 2-(4-fluoro-6-(metil-(2-(sulfatoetilsulfonil)etil)amino)-1,3,5-triazin-2-ilamino)-5-hidroksi-6-(4-metil-2-sulfonatofenilazo)naftalen-1,7-disulfonat (hr)
C&L Inventory
tetranatrio 2-(4-fluor-6-(metil-(2-(sulfatoetilsulfonil)etil)amino)-1,3,5-triazin-2-ilamino)-5-hidroksi-6-(4-metil-2-sulfonatofenilazo)naftalen-1,7-disulfonatas (lt)
C&L Inventory
tetranatrium 2-(4-fluori-6-(metyyli-(2-(sulfaattietyylisulfonyyli)etyyli)amino)-1,3,5-triatsin-2-ylamino)-5-hydroksi-6-(4-metyyli-2-sulfonaattifenylatso)naftaleeni-1,7-disulfonaatti (fi)
C&L Inventory
tetranatrium-2-(4-fluor-6-(methyl(2-(sulfatoethylsulfonyl)ethyl)amino)-1,3,5-triazine-2-ylamino)-5-hydroxy-6-(4-methyl-2-sulfonatofenylazo)naftaleen-1,7-disulfonaat (nl)
C&L Inventory
tetranatrium-2-(4-fluor-6-(methyl-(2-(sulfatoethylsulfonyl)ethyl)amino)-1,3,5-triazin-2-ylamino)-5-hydroxy-6-(4-methyl-2-sulfonatophenylazo)naphthalen-1,7-disulfonat (da)
C&L Inventory
tetranatrium-2-(4-fluor-6-(metyl-(2-(sulfatoetylsulfonyl)etyl)amino)-1,3,5-triazin-2-ylamino)-5-hydroksy-6-(4-metyl-2-sulfonatofenylazo)nafthalen-1,7-disulfonat (no)
C&L Inventory
tetranatrium-2-(4-fluoro-6-(metyl-(2-(sulfatoetylsulfonyl)etyl)amino)-1,3,5-triazin-2-ylamino)-5-hydroxi-6-(4-metyl-2-sulfonatofenylazo)naftalen-1,7-disulfonat (sv)
C&L Inventory
tetranatrium-2-{[4-fluor-6- (methyl{2-[(2-sulfatoethyl)sulfonyl] ethyl}- amino)-1,3,5-triazin-2- yl]amino}-5-hydroxy-6-[(4- methyl-2-sulfonatofenyl)azo] naftalen-1,7-disulfonát (cs)
C&L Inventory
tetranátrium 2-(4-fluor-6-(metil-(2-(szulfátoetil-szulfonil)etil)amino)-1,3,5-triazin-2-ilamino)-5-hidroxi-6-(4-metil-2-szulfonátofenilazo)naftalin-1,7-diszulfonát (hu)
C&L Inventory
tetranátrium-2-[4-fluór-6-(metyl{2-[2-(sulfonátooxy)etylsulfonyl]etyl}amino)-1,3,5-triazín-2-ylamino]-5-hydroxy-6-(4-metyl-2-sulfonátofenyldiazenyl)naftalén-1,7-disulfonát (sk)
C&L Inventory
tetranātrija 2-(4-fluor-6-(metil-(2-(sulfātetilsulfonil)etil)amino)-1,3,5-triazīn-2-ilamino)-5-hidroksi-6-(4-metil-2-sulfonātfenilazo)naftalīn-1,7-disulfonāts (lv)
C&L Inventory
тетранатриев 2-(4-флуоро-6-(метил-(2-сулфатоетилсулфонил)етил)амино)-1,3,5-триазин-2-иламино)-5-хидрокси-6-(4-метил-2-сулфонатофенилазо)нафтален-1,7-дисулфонат (bg)
C&L Inventory
1,7-Naphthalenedisulfonic acid, 2-[[4-fluoro-6-[methyl[2-[[2-(sulfooxy)ethyl]sulfonyl]ethyl]amino]-1,3,5-triazin-2-yl]amino]-5-hydroxy-6-[2-(4-methyl-2-sulfophenyl)diazenyl]-, sodium salt (1:4)
Other
Reaktiv Orange F 97-0318
Registration dossier
tetrasodium 2-({4-fluoro-6-[methyl({2-[2-(sulfooxy)ethanesulfonyl]ethyl})amino]-1,3,5-triazin-2-yl}amino)-5-hydroxy-6-[2-(4-methyl-2-sulfophenyl)diazen-1-yl]naphthalene-1,7-disulfonate
Other
243858-01-7
CAS number
C&L Inventory, Registration dossier, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties
607-645-00-2
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [1]
C Form
Powder (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Density

Study results
  • 2 studies submitted
  • 1 study processed
R Relative density
1.59 @ 23.2 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.59

Vapour pressure

Study results
  • 2 studies submitted
  • 1 study processed
R Vapour pressure
0.001 Pa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0.001 Pa @ 25 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
-6.2 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 2 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
210.58 g/L @ 20 °C and pH 6 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
210.58 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 1 study processed
R Surface tension
58.7 mN/m @ 1 g/L and 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
58.7 mN/m

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
252 °C

Flammability

Study results
  • 2 studies submitted
  • 1 study processed
C Interpretation of results
Non flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 1 study processed
C Interpretation of results
Non-explosive (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Data not provided by the registrant

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

Data not provided by the registrant

Short–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (48 h) 100 mg/L [1]
EC50 (24 h) 100 mg/L [1]
NOEC (48 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
100 mg/L

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 100 mg/L [1]
NOEC (72 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
100 mg/L
EC10 or NOEC for freshwater algae
100 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

Data not provided by the registrant

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Acute toxicity

Study results
oral
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: inhalation
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Genetic toxicity

Study results
Study data: in vitro
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
Study data: in vivo
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Data not provided by the registrant

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant