Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
295-446-8
CAS no.:
92045-64-2
Index number:
649-287-00-X
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
5
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic to aquatic life with long lasting effects, is a highly flammable liquid and vapour, is suspected of damaging fertility or the unborn child, causes skin irritation and may cause drowsiness or dizziness.

Breakdown of all 60 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Muta. 1B H340 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Aquatic Chronic 2 H411
Flam. Liq. 2 H225
Repr. 2 H361
Skin Irrit. 2 H315
STOT SE 3 H336
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (100% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is broad agreement in that a majority of data submitters agree this substance is Mutagenic (100% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 2 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels, air care products, anti-freeze products, coating products, lubricants and greases, washing & cleaning products and welding & soldering products.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and of substances in closed systems with minimal release.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid, outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, as processing aid and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, laboratory work, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, as processing aid, formulation of mixtures, formulation in materials, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; obtain special instructions before use; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. Do not induce vomiting.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Petroineos Manufacturing France SAS, Avenue de la Bienfaisance BP 6 133117 Lavera France
  • Total Raffinage France, 2, place Jean Millier, La Défense 92400 Courbevoie France
  • INEOS Services Belgium S.A, Rue de Ransbeek, 310 1120 Brussels Belgium
  • Total Petrochemicals France SA, Immeuble Le Linéa 1, rue du Général Leclerc 92047 Paris La Défence Cedex France

Substance names and other identifiers

[A complex combination of hydrocarbons obtained by the sorption of benzene from a catalytically fully hydrogenated benzene-rich hydrocarbon cut that was distillatively obtained from prehydrogenated cracked naphtha. It consists predominantly of paraffinic and naphthenic hydrocarbons having carbon numbers predominantly in the range of C6 through C7 and boiling in the range of approximately 70°C to 100°C (158°F to 212°F).]
A complex combination of hydrocarbons obtained by the sorption of benzene from a catalytically fully hydrogenated benzene-rich hydrocarbon cut that was distillatively obtained from prehydrogenated cracked naphtha. It consists predominantly of paraffinic and naphthenic hydrocarbons having carbon numbers predominantly in the range of C6 through C7 and boiling in the range of approximately 70°C to 100°C (158°F to 212°F).
C&L Inventory
Hydrocarbons, C6-7, naphtha-cracking, solvent-refined
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Hydrocarbons, C6-7, naphtha-cracking, solvent-refined
A complex combination of hydrocarbons obtained by the sorption of benzene from a catalytically fully hydrogenated benzene-rich hydrocarbon cut that was distillatively obtained from prehydrogenated cracked naphtha. It consists predominantly of paraffinic and naphthenic hydrocarbons having carbon numbers predominantly in the range of C6 through C7 and boiling in the range of approximately 70°C to 100°C (158°F to 212°F).
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Hydrocarbons, C6-7, naphtha-cracking, solvent-refined; Low boiling point modified naphtha [ complex combination of hydrocarbons obtained by the sorption of benzene from a catalytically fully hydrogenated benzene-rich hydrocarbon cut that was distillatively obtained from prehydrogenated cracked naphtha. It consists predomi nantly of paraffinic and naphthenic hydrocarbons having carbon numbers predominantly in the range of C6 through C7 and boiling in the range of approximately 70 °C to 100 °C (158°F to 212°F).]
A complex combination of hydrocarbons obtained by the sorption of benzene from a catalytically fully hydrogenated benzene-rich hydrocarbon cut that was distillatively obtained from prehydrogenated cracked naphtha. It consists predominantly of paraffinic and naphthenic hydrocarbons having carbon numbers predominantly in the range of C6 through C7 and boiling in the range of approximately 70°C to 100°C (158°F to 212°F).
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Hydrocarbons, C6-7, naphtha-cracking, solvent-refined; Low boiling point modified naphtha
A complex combination of hydrocarbons obtained by the sorption of benzene from a catalytically fully hydrogenated benzene-rich hydrocarbon cut that was distillatively obtained from prehydrogenated cracked naphtha. It consists predominantly of paraffinic and naphthenic hydrocarbons having carbon numbers predominantly in the range of C6 through C7 and boiling in the range of approximately 70°C to 100°C (158°F to 212°F).
FCM Active and Intelligent Materials - CMRs not allowed for use, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
Low boiling point modified naphtha
A complex combination of hydrocarbons obtained by the sorption of benzene from a catalytically fully hydrogenated benzene-rich hydrocarbon cut that was distillatively obtained from prehydrogenated cracked naphtha. It consists predominantly of paraffinic and naphthenic hydrocarbons having carbon numbers predominantly in the range of C6 through C7 and boiling in the range of approximately 70°C to 100°C (158°F to 212°F).
C&L Inventory
(Keerulise koostisega süsivesinike segu, mis saadakse eelhüdrogeenitud krakitud raskbensiini destillatsioonist saadud katalüütiliselt täielikult hüdrogeenitud benseenirikkast süsivesinikfraktsioonist benseeni sorptsioonil. Koosneb peamiselt parafiinsetest ja nafteensetest süsivesinikest, mille süsiniku aatomite arv on valdavalt vahemikus C6 kuni C7, ning on keemistemperatuuriga umbes 70°C kuni 100 °C.) (et)
C&L Inventory
(Složeni sastav ugljikovodika dobiven sorpcijom benzena iz potpuno katalitički hidrogeniranoga benzenom bogatog ugljikovodičnog reza koji je dobiven destilacijskim putem iz prethodno hidrogeniranog krekiranog benzina. Sastoji se pretežito od parafinskih i naftenskih ugljikovodika koji imaju broj ugljikovih atoma pretežito u području od C6 do C7 i vriju u području približno od 70 ºC do 100 ºC.) (hr)
C&L Inventory
[Kompleks blanding av hydrokarboner dannet ved sorpsjon av benzen fra en katalytisk, fullhydrogenert, benzenrik hydrokarbonfraksjon som er dannet ved destillasjon fra prehydrogenert, krakket nafta. Består for det meste av paraffin- og naftenhydrokarboner, hovedsakelig C6 til C7, med omtrentlig kokepunktsintervall fra 70 °C til 100 °C (158 °F til 212 °F).] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov dobljena s absorbcijo benzena iz katalitsko popolnoma hidrogeniranega benzena - z ogljikovodiki bogate frakcije, ki je bila dobljena z destilacijo iz prehidrogenirane krekirane nafte. Sestoji pretežno iz parafinskih in naftenskih ogljikovodikov s številom ogljikovih atomov pretežno med C6 in C7 ter z vreliščem v območju približno med 70 °C in 100 °C.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen, erhalten durch Sorption von Benzol aus einem katalytisch voll hydrierten benzolreichen Kohlenwasserstoffschnitt, hergestellt durch Destillation von vorhydriertem gekracktem Naphtha; besteht vorwiegend aus Paraffinen und Naphthenen mit Kohlenstoffzahlen überwiegend im Bereich von C6 bis C7 mit einem Siedebereich von etwa 70 °C bis 100 °C] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná sorpciou benzénu z katalyticky úplne hydrogenovanej uhľovodíkovej frakcie s vysokým obsahom benzénu, vydestilovanej z predhydrogenovaného krakovaného ťažkého benzínu. Pozostáva predovšetkým z alkánových a cykloalkánových uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C6 do C7. Má teplotu varu v rozmedzí približne od 70 °C do 100 °C.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi obţinute prin absorbţia benzenului din fracţia de hidrocarbura bogata în benzen şi hidrogenată catalitic complet, obţinută prin distilarea ţiţeiului cracat prehidrogenat. Constă în principal din hidrocarburi parafinoase si naftenice, al căror număr de atomi de carbon variază în principal între C6 şi C7, şi al căror punct de fierbere este cuprins între aproximativ 70°C şi 100°C (158°F şi 212°F).] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts, absorbējot benzolu no katalītiski pilnībā hidrogenētas, ar benzolu bagātas ogļūdeņražu frakcijas, kas iegūta, destilējot prehidrogenēti sašķeltu ligroīnu. Sastāv galvenokārt no parafīnu un naftēnu rindas ogļūdeņražiem, pārsvarā ar oglekļa atomu skaitu no C6 līdz C7, aptuvenā viršanas temperatūra no 70°C līdz 100°C (158°F līdz 212°F).] (lv)
C&L Inventory
[Složitá směs uhlovodíků získaná sorpcí benzenu z katalyticky plně hydrogenované, na benzen bohaté uhlovodíkové frakce, která byla získána destilačně z předhydrogenovaného krakovaného benzínu. Je složena převážně z parafinických a naftenických uhlovodíků s počtem uhlíkových atomů převážně v rozmezí C6 až C7 s rozmezím teploty varu přibližně 70 °C až 100 °C.] (cs)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas sorbavus benzeną iš daug benzeno turinčios visiško katalizinio hidrinimo angliavandenilių frakcijos, kuri distiliavimo būdu buvo gauta iš pradinio hidrokrekingo pirminio benzino. Jį sudaro daugiausia alkanų ir naftenų angliavandeniliai, turintys anglies atomų skaičių daugiausia nuo C6 iki C7, ir kurių virimo temperatūra maždaug nuo 70 °C iki 100 °C (nuo 158 °F iki 212 °F).] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet előhidrogénezett krakkolt benzinből desztillációs úton nyert, katalitikusan teljesen hidrogénezett, benzolban gazdag frakcióból állítanak elő a benzol szorpciójával. Főleg paraffinos és nafténes szénhidrogénekből áll, melyek szénatomszáma a C6-C7 tartományban van, és kb. a 70°C-tól 100°C-ig (158°F-től 212°F-ig) terjedő tartományban forr.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που λαμβάνεται με ρόφηση του βενζολίου ενός κλάσματος υδρογονανθράκων, πλούσιου σε βενζόλιο, το οποίο έχει πλήρως υδρογονωθεί καταλυτικά και έχει ληφθεί με απόσταξη από πυρολυμένη νάφθα μετά από υδρογόνωση. Συνίσταται κυρίως από παραφινικούς και ναφθενικούς υδρογονάνθρακες με αριθμό ατόμων άνθρακα κυρίως μεταξύ C6 και C7 που αποστάζουν μεταξύ 70 °C και 100 °C περίπου.] (el)
C&L Inventory
[Комплексна комбинация от въглеводороди, получена при сорбцията на бензен от каталитично напълно хидрогенирана, богата на бензен въглеводородна фракция, която е получена при дестилация от предварително хидрогениран нискооктанов бензин от крекинг процес. Състои се основно от парфинови и нафтенови въглеводороди с брой на въглеродните атоми преобладаващо в интервала от С6 до C7 вкючително и с температура на кипене приблизително в интервала от 70°C до 100°C (158°F до 212°F).] (bg)
C&L Inventory
Alacsony forráspontú módosított benzin (hu)
C&L Inventory
Angliavandeniliai, C6-7, pirminio benzino krekingas, valyti tirpikliais (lt)
C&L Inventory
C6-7-uhľovodíky, z krakovania ťažkého benzínu, rafinované rozpúšťadlom (sk)
C&L Inventory
carbonhydrider, C6-7 naphthakraknings, solventraffinerede (da)
C&L Inventory
combinación compleja de hidrocarburos obtenida por absorción de benceno de una fracción hidrocarbonada rica en benceno totalmente hidrogenada catalíticamente que se había obtenido por destilación de nafta craqueada y prehidrogenada; compuesta principalmente de hidrocarburos parafínicos y nafténicos con un número de carbonos en su mayor parte dentro del intervalo de C6 a C7 y con un intervalo de ebullición aproximado de 70 °C a 100 °C (es)
C&L Inventory
Combinaison complexe d'hydrocarbures obtenue par absorption du benzène dans une coupe d'hydrocarbures riche en benzène ayant subi une hydrogénation catalytique complète, cette coupe résultant de la distillation de naphta de craquage préalablement hydrogéné. Se compose principalement d'hydrocarbures paraffiniques et naphténiques dont le nombre de carbones se situe en majorité dans la gamme C6-C7 et dont le point d'ébullition est compris approximativement entre 70°C et 100°C. (fr)
C&L Inventory
Combinazione complessa di idrocarburi ottenuta mediante assorbimento di benzene da un taglio idrocarburico ricco di benzene completamente idrogenato cataliticamente che era stato ottenuto mediante distillazione da nafta crackizzata preidrogenata. È costituita in prevalenza da idrocarburi paraffinici e naftenici con un numero di atomi di carbonio prevalentemente nell'intervallo C6-7 e con punto di ebollizione nell'intervallo 70 °C - 100 °C ca. (da 158°F a 212°F). (it)
C&L Inventory
Combinação complexa de hidrocarbonetos obtida por sorção de benzeno de uma fracção de hidrocarbonetos totalmente hidrogenados cataliticamente, rica em benzeno, obtida por destilação dos produtos do cracking de nafta previamente hidrogenados. É constituída predominantemente por hidrocarbonetos parafínicos e nafténicos com número de átomos de carbono predominantemente na gama C6 a C7 e destilação no intervalo aproximado de 70 °C a 100 °C. (pt)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen door sorptie van benzeen uit een katalytisch volledig gehydrogeneerde benzeenrijke koolwaterstoffractie die door destillatie is verkregen uit voorgehydrogeneerde gekraakte nafta. Bestaat voornamelijk uit paraffine- en nafteenkoolwaterstoffen, overwegend C6 en C7, met een kooktraject van ongeveer 70°C tot 100°C. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider opnået ved sorptionen af benzen fra en katalytisk, fuldt hydrogeneret, benzen-rig carbonhydridfraktion, opnået ved destillation af præhydrogeneret, krakket naphtha. Den består overvejende af paraffin- og naphthencarbonhydrider, overvejende C6 til og med C7, med kogeinterval omtrent fra 70 °C til 100 °C (158 ºF til 212 ºF). (da)
C&L Inventory
Fracţia nafta modificată cu punct de fierbere la temperaturi scăzute (mt)
C&L Inventory
Fracţia nafta modificată cu punct de fierbere la temperaturi scăzute (ro)
C&L Inventory
Gemodificeerde nafta met laag kookpunt (nl)
C&L Inventory
Hidrocarbonetos, C6-7, do cracking de nafta, refinados com solventes (pt)
C&L Inventory
Hidrocarburi, C6-7, fracţia nafta de cracare, rafinare cu solvent (mt)
C&L Inventory
Hidrocarburi, C6-7, fracţia nafta de cracare, rafinare cu solvent (ro)
C&L Inventory
hidrocarburos, C6-7, craqueo de nafta, refinados con disolvente (es)
C&L Inventory
Hiilivedyt, C6-7, teollisuusbensiinikrakkaus, liuotinjalostettu (fi)
C&L Inventory
Hydrocarbures en C6-7, craquage de naphta, raffinés au solvant;naphta modifié à bas point d'ébullition;[combinaison complexe d'hydrocarbures obtenue par sorption du benzène contenu dans une coupe d'hydrocarbures riche en benzène ayant subi une hydrogénation catalytique complète et résultant de la distillation de naphta de craquage préalablement préhydrogéné. Se compose principalement d'hydrocarbures paraffiniques et naphténiques comportant majoritairement entre 6 et 7 atomes de carbone (C6-C7) et dont l'intervalle d'ébullition est compris approximativement entre 70 et 100 oC (entre 158 et 212o F).] (fr)
C&L Inventory
hydrokarboner, C6-7, naftakrakking, solventraffinerte (no)
C&L Inventory
idrocarburi, C6-7, da cracking di nafta, raffinati con solventi (it)
C&L Inventory
Kohlenwasserstoffe, C6-7, Naphthakracken, Lösungsmittelraffination (de)
C&L Inventory
Kolväten, C6-7-, naftakrackning, lösningsmedelsraffinerade (sv)
C&L Inventory
Komplex blandning av kolväten erhållen genom sorption av bensen från en katalytiskt fullt hydrogenerad bensenrik kolvätefraktion som erhållits genom destillation från prehydrogenerad krackad nafta. Består främst av paraffin- och naftenkolväten, i synnerhet C6 till C7, med ungefärligt kokpunktsintervall från 70 °C till 100 °C. (sv)
C&L Inventory
Koolwaterstoffen, C6-7, naftakraken, oplosmiddelgeraffineerd (nl)
C&L Inventory
Lavtkogende modificeret nafta (da)
C&L Inventory
lavtkokende modifisert nafta (no)
C&L Inventory
Lågkokande modifierad nafta (sv)
C&L Inventory
Madala keemispunktiga modifitseeritud raskbensiin (et)
C&L Inventory
Matalalla kiehuva modifioitu teollisuusbensiini (fi)
C&L Inventory
modificirana nafta z nizko temperaturo vrelišča (sl)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu bentseenin sorptiolla katalyyttisesti täysin hydratusta bentseenirikkaasta hiilivetyjakeesta, joka on saatu tislaten esihydratusta krakatusta teollisuusbensiinistä. Koostuu pääasiassa parafiinisista ja nafteenisista hiilivedyistä, joiden hiililuvut ovat pääasiassa välillä C6:sta C7:ään ja jotka kiehuvat likimäärin välillä 70°C:sta 100°C:een. (158°F:sta 212°F:iin). (fi)
C&L Inventory
Nafta modificada de baixo ponto de ebulição (pt)
C&L Inventory
nafta modificada de bajo punto de ebullición (es)
C&L Inventory
nafta modificata con basso punto di ebollizione (it)
C&L Inventory
naphta modifié à point d'ébullition bas (fr)
C&L Inventory
Naphtha, niedrigsiedend, modifiziert (de)
C&L Inventory
Nisko-vrijući modificirani benzin (hr)
C&L Inventory
Niskowrząca modyfikowana frakcja benzynowa (pl)
C&L Inventory
Nízkovroucí modifikovaná benzínová frakce (cs)
C&L Inventory
O combinaţie complexă de hidrocarburi obţinute prin absorbţia benzenului din fracţia de hidrocarbura bogata în benzen şi hidrogenată catalitic complet, obţinută prin distilarea ţiţeiului cracat prehidrogenat. Constă în principal din hidrocarburi parafinoase si naftenice, al căror număr de atomi de carbon variază în principal între C6 şi C7, şi al căror punct de fierbere este cuprins între aproximativ 70°C şi 100°C (158°F şi 212°F). (mt)
C&L Inventory
ogljikovodiki, C6-7, naftni kreking, rafinirani s topilom (sl)
C&L Inventory
Ogļūdeņraži, C6-7, krekinga ligroīns, attīrīts ar šķīdinātāju (lv)
C&L Inventory
Szénhidrogének, C6-7, benzin krakkolás, oldószerrel finomított (hu)
C&L Inventory
Süsivesinikud, C6–7, raskbensiini krakkimine, lahusti-rafineeritud (et)
C&L Inventory
Ugljikovodici, C6-7, kreking benzin, otapalom rafiniran (hr)
C&L Inventory
Uhlovodíky, C6-7, krakování těžkého benzínu, rozpouštědlově rafinované (cs)
C&L Inventory
upravený benzín s nízkou teplotou varu (sk)
C&L Inventory
Węglowodory C6-7 rafinowane rozpuszczalnikiem, pochodzące z instalacji uwodornienia benzenu (pl)
C&L Inventory
Zemā temperatūrā virstošs modificēts ligroīns (lv)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana przez sorpcję benzenu z katalitycznie całkowicie uwodornionej frakcji bogatej w benzen wydestylowanej z wstępnie uwodornionej krakowanej benzyny ciężkiej. Składa się przede wszystkim z parafinowych i naftenowych węglowodorów o liczbie atomów węgla w głównie zakresie od C6 do C7, wrzących w zakresie temp. od ok. 70°C do 100°C. (pl)
C&L Inventory
Žematemperatūris modifikuotas pirminis benzinas (lt)
C&L Inventory
Τροποποιημένη νάφθα χαμηλού σημείου ζέσεως (el)
C&L Inventory
υδρογονάνθρακεςΥδρογονάνθρακες, C6-7, πυρόλυσης νάφθας, εξευγενισμένοι με διαλύτη (el)
C&L Inventory
Въглеводороди, C6-7, от крекинг процес на нискооктанов бензин, рафинирани с разтворител (bg)
C&L Inventory
Модифициран нискооктанов бензин с ниска температура на кипене (bg)
C&L Inventory
Hydrocarbons, C6-7, naphtha-cracking, solvent-refined
Other
Benzene Raffinate
Registration dossier
Benzene Raffinate (Raffinate 3)
Registration dossier
Hydrocarbons, C6-7, naphta-cracking, solvent-refined
Registration dossier
Hydrocarbons, C6-7, naphtha-cracking, solvent-refined
C&L Inventory, Registration dossier
Coupe C6
Registration dossier
Raffinat C6
Registration dossier
Raffinate C6
Registration dossier
649-287-00-X
Index number
C&L Inventory
92045-64-2
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Other (100%) [1]
C Substance type
Petroleum product (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
-60 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 2 studies submitted
  • 1 study processed
R Boiling point
-20 - 260 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 1 study submitted
  • 1 study processed
R Relative density
0.62 - 0.88 @ 15 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
240 kPa @ 37.8 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 1 study submitted
  • 1 study processed
R Flash point
-40 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 4 studies submitted
  • 2 studies processed
R Autoflammability / self-ignition
280 - 470 °C @ 101.3 - 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Extremely flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 1 study processed
R kinematic viscosity (in mm²/s)
1 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning Insufficient hazard data available (further information necessary) (1)

Short–term toxicity to fish

Study results
  • 16 studies submitted
  • 2 studies processed
P/RResults
LL50 (4 days) 8.2 - 10 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 14
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EL50 (21 days) 10 mg/L [1]
NOELR (21 days) 2.6 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 12 studies submitted
  • 1 study processed
P/RResults
EL50 (48 h) 4.5 mg/L [1]
NOELR (48 h) 500 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 11
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
NOELR (21 days) 2.6 - 16 mg/L [2]
EL50 (21 days) 10 - 40 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 16 studies submitted
  • 1 study processed
P/RResults
EL50 (4 days) 3.7 mg/L [1]
EL50 (72 h) 3.1 mg/L [1]
NOELR (72 h) 500 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 15
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (40 h) 15.41 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.9 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 286.4 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 837.5 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1 066.67 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 410 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 152 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 178.57 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 640 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 43 studies submitted
  • 1 study processed
P/RResults
LD50 5 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 2 40
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 39 studies submitted
  • 1 study processed
M/CInterpretations of results
Not classified [1]

inhalation
Studies with data
Key study 1
Supporting study 38
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 44 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study 43
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5 610 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 95 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 3 90
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 45 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 43
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 43 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 41
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 22 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study 1
Supporting study 21
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 50 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study 1
Supporting study 49
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 402 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 18
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 13
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 2 8
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route:
No adverse effect observed NOAEC 9 869 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Inhalation route:
No adverse effect observed NOAEC 20 000 mg/m³ (chronic, rat)
Effect on developmental toxicity
Dermal route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 23 900 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant