Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
295-438-4
CAS no.:
92045-57-3
Index number:
649-339-00-1
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
4
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance causes damage to organs through prolonged or repeated exposure, is very toxic to aquatic life with long lasting effects, is toxic in contact with skin, is toxic if inhaled, is toxic if swallowed, is very toxic to aquatic life, is suspected of damaging fertility or the unborn child, causes serious eye irritation, is a highly flammable liquid and vapour, may cause respiratory irritation, causes skin irritation, may cause an allergic skin reaction and may cause drowsiness or dizziness.

Breakdown of all 25 C&L notifications submitted to ECHA

Repr. 2 H361
Aquatic Chronic 2 H411
Eye Irrit. 2 H319
STOT RE 1 H372
Acute Tox. 4 H312
STOT RE 2 H373
STOT SE 3 H335
Asp. Tox. 1 H304 Harmonised Classification
Muta. 1B H340 Harmonised Classification
Acute Tox. 3 H331
Carc. 1A H350
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Acute Tox. 4 H302
Acute Tox. 4 H332
https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (25% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Mutagenic (25% of REACH registrations).
  • Ss
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Skin sensitising (25% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 3 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 to < 10 tonnes per annum.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and transfer of chemicals.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, transfer of chemicals, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates) and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; take actions to prevent static discharges; do not breathe the dust, fume, gas, mist, vapours or spray; contaminated work clothing should not be allowed out of the workplace; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use only outdoors or in a well-ventilated area; obtain special instructions before use; do not eat, drink or smoke when using this product; avoid release to the environment; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier; avoid breathing the dust, fume, gas, mist, vapours or spray.

Response statements

In case of incident: Wash contaminated clothing before reuse. If swallowed: immediately call a poison center or doctor/physician. If exposed or concerned: get medical advice/attention. Get medical advice/attention if you feel unwell. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Collect spillage. If swallowed: rinse mouth. Do not induce vomiting. If inhaled: call a poison center or doctor/physician if you feel unwell. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. If eye irritation persists get medical advice/attention. Rinse the mouth. Do not induce vomiting. If swallowed: call a poison center or doctor/physician if you feel unwell. Follow specific treatment (see label).

Storage statements

Store this substance in a dry place; locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Borealis Polymers Oy, P.O. Box 330 06101 Porvoo Finland
  • Total Olefins Antwerp, Scheldelaan 10 2030 Antwerpen Belgium
  • Total Raffinage France, 2, place Jean Millier, La Défense 92400 Courbevoie France

Substance names and other identifiers

[A complex combination of hydrocarbons obtained by treating a petroleum fraction, derived from a pyrolysis process, with hydrogen in the presence of a catalyst. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).]
A complex combination of hydrocarbons obtained by treating a petroleum fraction, derived from a pyrolysis process, with hydrogen in the presence of a catalyst. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
C&L Inventory
Low boiling point hydrogen treated naphtha
A complex combination of hydrocarbons obtained by treating a petroleum fraction, derived from a pyrolysis process, with hydrogen in the presence of a catalyst. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
C&L Inventory
Naphtha (petroleum), hydrotreated light steam-cracked
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), hydrotreated light steam-cracked
A complex combination of hydrocarbons obtained by treating a petroleum fraction, derived from a pyrolysis process, with hydrogen in the presence of a catalyst. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), hydrotreated light steam-cracked; Low boiling point hydrogen treated naphtha [ complex combination of hydrocarbons obtained by treating a petroleum fraction, derived from a pyrolysis process, with hydrogen in the presence of a catalyst. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190 °C (95°F to 374°F).]
A complex combination of hydrocarbons obtained by treating a petroleum fraction, derived from a pyrolysis process, with hydrogen in the presence of a catalyst. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Naphtha (petroleum), hydrotreated light steam-cracked; Low boiling point hydrogen treated naphtha
A complex combination of hydrocarbons obtained by treating a petroleum fraction, derived from a pyrolysis process, with hydrogen in the presence of a catalyst. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
FCM Active and Intelligent Materials - CMRs not allowed for use, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
(Keerulise koostisega süsivesinike segu, mis saadakse pürolüüsil saadava naftafraktsiooni katalüütilisel hüdrogeenimisel. Koosneb peamiselt küllastumata süsivesinikest, mille süsiniku aatomite arv on valdavalt vahemikus C5 kuni C11, ning on keemistemperatuuriga umbes 35°C kuni 190 °C.) (et)
C&L Inventory
(Složeni sastav ugljikovodika dobiven obradom naftne frakcije iz postupka pirolize vodikom u prisutnosti katalizatora. Sastoji se pretežito od nezasićenih ugljikovodika koji imaju broj ugljikovih atoma pretežito u području od C5 do C11 i vriju u području približno od 35 °C do 190 °C.) (hr)
C&L Inventory
[Kompleks blanding av hydrokarboner dannet ved å behandle en petroleumsfraksjon, fremstilt ved en pyrolyseprosess, med hydrogen i nærvær av en katalysator. Består for det meste av umettede hydrokarboner, hovedsakelig C5 til C11, med omtrentlig kokepunktsintervall fra 35 °C til 190 °C (95 °F til 374 °F).] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov dobljena z obdelavo frakcije zemeljskega olja, ki jo dobimo v procesu pirolize, z vodikom v prisotnosti katalizatorja. Sestoji pretežno iz nenasičenih ogljikovodikov s številom ogljikovih atomov pretežno v območju med C5 in C11 ter ima vrelišče v območju približno med 35 °C in 190 °C.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen, erhalten durch Wasserstoffbehandlung einer aus Pyrolyse stammenden Erdölfraktion unter Einsatz eines Katalysators; besteht vorwiegend aus ungesättigten Kohlenwasserstoffen mit Kohlenstoffzahlen überwiegend im Bereich von C5 bis C11 mit einem Siedebereich von etwa 35 °C bis 190 °C] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná ktalytickou hydrogenáciou ropnej frakcie, získanej pyrolýzou. Pozostáva predovšetkým z nenasýtených uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C5 do C11. Má teplotu varu v rozmedzí približne od 35 °C do 190 °C.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi obţinută prin tratarea fracţiei petroliere derivată dintr-un proces de piroliză, cu hidrogen în prezenţa unui catalizator. Constă cu precădere în hidrocarburi nesaturate al căror număr de atomi de carbon variază între C5 şi C11 şi al căror punct de fierbere este cuprins între 35°C şi 190°C (95°F şi 374°F).] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts, pirolīzes procesam pakļauto naftas frakciju katalītiski apstrādājot ar ūdeņradi. Sastāv pārsvarā no nepiesātinātiem ogļūdeņražiem ar oglekļa atomu skaitu pārsvarā no C5 līdz C11, aptuvenā viršanas temperatūra no 35°C līdz 190°C (95°F līdz 374°F).] (lv)
C&L Inventory
[Složitá směs uhlovodíků získaná katalytickou hydrogenací ropné frakce z pyrolýzy. Je složena převážně z nenasycených uhlovodíků s počtem uhlíkových atomů převážně v rozmezí C5 až C11 a s rozmezím teplot varu přibližně 35 °C až 190 °C.] (cs)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas apdorojant vandeniliu pirolizės procese gautą naftos frakciją, esant katalizatoriui. Jį sudaro daugiausia nesotieji angliavandeniliai, turintys anglies atomų skaičių daugiausia nuo C5 iki C11, ir kurių virimo temperatūra maždaug nuo 35 °C iki 190 °C (nuo 95 °F iki 374 °F).] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet pirolízisből származó nyersolaj frakció katalizátor jelenlétében végzett hidrogénezésével nyernek. Főleg telítetlen szénhidrogénekből áll, melyek szénatomszáma főleg a C5-C11 tartományban van. Forrásponttartománya kb. 35°C-tól 190°C-ig (95°F-től 374°F-ig) terjed.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που λαμβάνεται με κατεργασία κλάσματος πετρελαίου, το οποίο προέρχεται από διεργασία πυρόλυσης με υδρογόνο παρουσία καταλύτη. Συνίσταται κυρίως από ακόρεστους υδρογονάνθρακες με αριθμό ατόμων άνθρακα κυρίως μεταξύ C5 και C11 που αποστάζουν μεταξύ 35 °C και 190 °C περίπου.] (el)
C&L Inventory
[Комплексна комбинация от въглеводороди , получена при обработване на нефтена фракция, получена при пиролизен процес, с водород в присъствие на катализатор. Състои се основно от ненаситени въглеводороди с брой на въглеродните атоми преобладаващо в интервала от C5 до C11 включително и с температура на кипене приблизително в интервала от 35°C до 190°C (95°F до 374°F).] (bg)
C&L Inventory
Alacsony forráspontú hidrogénnel kezelt benzin (hu)
C&L Inventory
Benzin (nafta), hidroobrađen laki parom krekiran (hr)
C&L Inventory
Benzin (nyersolaj), hidrogénnel kezelt könnyű gőzkrakkolt (hu)
C&L Inventory
Benzyna (ropa naftowa), uwodornione produkty lekkie z olefin (pl)
C&L Inventory
Benzínová frakce (ropná), hydrogenačně odsířená, lehká pyrolyzní (cs)
C&L Inventory
combinación compleja de hidrocarburos obtenida por el tratamiento de una fracción de petróleo, derivada de un proceso de pirolisis, con hidrógeno en presencia de un catalizador; compuesta principalmente de hidrocarburos insaturados con un número de carbonos en su mayor parte dentro del intervalo de C5 a C11 y con un intervalo de ebullición aproximado de 35 °C a 190 °C (es)
C&L Inventory
Combinaison complexe d'hydrocarbures obtenue par traitement à l'hydrogène en présence d'un catalyseur d'une fraction pétrolière dérivée d'une pyrolyse. Se compose principalement d'hydrocarbures insaturés dont le nombre de carbones se situe en majorité dans la gamme C5-C11 et dont le point d'ébullition est compris approximativement entre 35°C et 190°C. (fr)
C&L Inventory
Combinazione complessa di idrocarburi ottenuta per trattamento di una frazione di petrolio, derivata da un processo di pirolisi, con idrogeno in presenza di un catalizzatore. È costituita in prevalenza da idrocarburi insaturi con un numero di atomi di carbonio prevalentemente nell'intervallo C5-11 e con punto di ebollizione nell'intervallo 35 °C - 190 °C ca. (da 95°F a 374°F). (it)
C&L Inventory
Combinação complexa de hidrocarbonetos obtida por tratamento com hidrogénio, na presença de um catalisador, de uma fracção petrolífera proveniente de um processo de pirólise. É constituída predominantemente por hidrocarbonetos insaturados com número de átomos de carbono predominantemente na gama C5 a C11 e destilação no intervalo aproximado de 35 °C a 190 °C. (pt)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen door waterstofbehandeling van een aardoliefractie, afkomstig uit een pyrolyseproces, in aanwezigheid van een katalysator. Bestaat voornamelijk uit onverzadigde koolwaterstoffen, overwegend C5 tot en met C11, met een kooktraject van ongeveer 35°C tot 190°C. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider opnået ved at behandle en råoliefraktion, fremkommet ved en pyrolyseproces, med hydrogen i tilstedeværelse af en katalysator. Den består overvejende af umættede carbonhydrider, overvejende C5 til og med C11, med kogeinterval omtrent fra 35 °C til 190 °C (95 ºF til 374 ºF). (da)
C&L Inventory
Fracţia nafta (petrol), cracată cu vapori, uşor hidrogenată (mt)
C&L Inventory
Fracţia nafta (petrol), cracată cu vapori, uşor hidrogenată (ro)
C&L Inventory
Fracţia nafta tratată cu hidrogen şi care are punct de fierbere la temperaturi scăzute (mt)
C&L Inventory
Fracţia nafta tratată cu hidrogen şi care are punct de fierbere la temperaturi scăzute (ro)
C&L Inventory
Gehydrogeneerde nafta met laag kookpunt (nl)
C&L Inventory
Hidrogenēts ligroīns ar zemu viršanas temperatūru (lv)
C&L Inventory
hydrogenovaný ťažký benzín s nízkou teplotou varu (sk)
C&L Inventory
Komplex blandning av kolväten erhållen genom behandling av en petroleumfraktion, erhållen genom en pyrolysprocess, med väte i närvaro av katalysator. Består främst av omättade kolväten, i synnerhet C5 till C11, med ungefärligt kokpunktsintervall från 35 °C till 190 °C. (sv)
C&L Inventory
Lavtkogende hydrogeneret nafta (da)
C&L Inventory
lavtkokende hydrogenbehandlet nafta (no)
C&L Inventory
Ligroīns (nafta), apstrādāts ar ūdeņradi, vieglais, pakļauts tvaika krekingam (lv)
C&L Inventory
Lågkokande vätebehandlad nafta (sv)
C&L Inventory
Madala keemispunktiga hüdrogeenitud raskbensiin (et)
C&L Inventory
Matalalla kiehuva vetykäsitelty teollisuusbensiini (fi)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu käsittelemällä maaöljyfraktiota, joka on johdettu pyrolyysiprosessista, vedyllä katalyytin läsnäollessa. Koostuu pääasiassa tyydyttymättömistä hiilivedyistä, joiden hiililuvut ovat pääasiassa välillä C5:stä C11:aan ja jotka kiehuvat likimäärin välillä 35°C:sta 190°C:een (95°F:sta 374°F:iin). (fi)
C&L Inventory
Nafta (aardolie), met stoom gekraakte lichte fractie, waterstofbehandeld (nl)
C&L Inventory
nafta (petroleum), hydrogenbehandlet lett dampkrakket (no)
C&L Inventory
Nafta (petroleum), vätebehandlad, lätt, ångkrackad (sv)
C&L Inventory
nafta (petrolio), leggera da steam cracking sottoposta a hydrotreating (it)
C&L Inventory
nafta (petróleo), fracción ligera craqueada a vapor tratada con hidrógeno (es)
C&L Inventory
Nafta (petróleo), fracção leve de steam cracking tratada com hidrogénio (pt)
C&L Inventory
nafta (zemeljsko olje), obdelana z vodikom, lahka, parno krekirana (sl)
C&L Inventory
Nafta de baixo ponto de ebulição tratada com hidrogénio (pt)
C&L Inventory
nafta di hydrotreating con basso punto di ebollizione (it)
C&L Inventory
nafta tratada con hidrógeno de bajo punto de ebullición (es)
C&L Inventory
naphta hydrotraité à point d'ébullition bas (fr)
C&L Inventory
Naphta léger de vapocraquage (pétrole), hydrotraité;naphta hydrotraité à bas point d'ébullition;[combinaison complexe d'hydrocarbures obtenue par traitement à l'hydrogène, en présence d'un catalyseur, d'une fraction pétrolière dérivée d'une pyrolyse. Se compose principalement d'hydrocarbures insaturés comportant majoritairement entre 5 et 11 atomes de carbone (C5-C11) et dont l'intervalle d'ébullition est compris approximativement entre 35 et 190 oC (entre 95 et 374o F).] (fr)
C&L Inventory
Naphtha (Erdöl), wasserstoffbehandelt, leicht, dampfgekrackt (de)
C&L Inventory
naphtha (råolie), hydrogenbehandlet let dampkrakket (da)
C&L Inventory
Naphtha, wasserstoffbehandelt, niedrigsiedend (de)
C&L Inventory
Nisko-vrijući hidroobrađen benzin (hr)
C&L Inventory
Niskowrząca frakcja naftowa obrabiana wodorem (pl)
C&L Inventory
Nízkovroucí hydrogenovaná benzínová frakce (cs)
C&L Inventory
O combinaţie complexă de hidrocarburi obţinută prin tratarea fracţiei petroliere derivată dintr-un proces de piroliză, cu hidrogen în prezenţa unui catalizator. Constă cu precădere în hidrocarburi nesaturate al căror număr de atomi de carbon variază între C5 şi C11 şi al căror punct de fierbere este cuprins între 35°C şi 190°C (95°F şi 374°F). (mt)
C&L Inventory
Pirminis benzinas (nafta), hidrintas lengvasis, krekingo vandens garais (lt)
C&L Inventory
Raskbensiin (nafta), hüdrogeenitud, kerge, aurkrakitud (et)
C&L Inventory
Teollisuusbensiini (maaöljy), vetykäsitelty kevyt höyrykrakattu (fi)
C&L Inventory
z vodikom obdelana nafta z nizko temperaturo vrelišča (sl)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana przez obróbkę wodorem frakcji ropy naftowej pochodzącej z procesu pirolizy w obecności katalizatora. Składa się przede wszystkim z nienasyconych węglowodorów o liczbie atomów węgla głównie w zakresie od C5 do C11 wrzących w zakresie temp. od ok. 35°C do 190°C. (pl)
C&L Inventory
ťažký benzín (ropný), ľahká frakcia, z hydrogenácie po parnom krakovaní (sk)
C&L Inventory
Žematemperatūris hidrintas pirminis benzinas (lt)
C&L Inventory
Νάφθα χαμηλού σημείου ζέσεως από υδρογονοεπεξεργασία (el)
C&L Inventory
νάφθαΝάφθα (πετρελαίου), ελαφρά, ατμοπυρολυμένη, υδρογονοκατεργασμένη (el)
C&L Inventory
Нискооктанов бензин (нефт), обработен с водород, лек от паров крекинг (bg)
C&L Inventory
Обработен с водород нискооктанов бензин с ниска температура на кипене (bg)
C&L Inventory
Naphtha (petroleum), hydrotreated light steam-cracked
Other
Naphtha (petroleum), hydrotreated light steam cracked
Registration dossier
Naphtha (petroleum), hydrotreated light steam cracked
Registration dossier
Naphtha (petroleum), hydrotreated light steam-cracked
C&L Inventory, Registration dossier
Naphtha (petroleum), hydrotreated light steam-cracked
Registration dossier
DPG II product, benzene rich
Registration dossier
Hydrotreated C5-C9
Registration dossier
Hydrotreated C9
Registration dossier
hydrotreated Gasoline (C5C9 cut)
Registration dossier
649-339-00-1
Index number
C&L Inventory
92045-57-3
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 24 studies submitted
  • 23 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [23]
C Form
Other (89%), Viscous (11%) [9]
C Odour
Characteristic of aromatic compounds (76%), Other (19%) [21]
C Substance type
Petroleum product (62%), Organic (38%) [21]

Type of Study provided
Studies with data
Key study 6 17
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 7 studies submitted
  • 6 studies processed
R Melting / freezing point
-100 - -29 °C @ 101.3 kPa [8]

Type of Study provided
Studies with data
Key study 6
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-66.9 °C

Boiling point

Study results
  • 21 studies submitted
  • 13 studies processed
R Boiling point
54.3 - 260 °C @ 100.7 - 101.33 kPa [15]

Type of Study provided
Studies with data
Key study 9 5
Supporting study 1 6
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
142 °C

Density

Study results
  • 13 studies submitted
  • 5 studies processed
R Relative density
0.83 - 0.89 @ 20 °C [5]

Type of Study provided
Studies with data
Key study 6
Supporting study 1 6
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.87

Vapour pressure

Study results
  • 29 studies submitted
  • 21 studies processed
R Vapour pressure
4 - 550 hPa @ 20 - 50 °C [29]

Type of Study provided
Studies with data
Key study 21
Supporting study 3 5
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
11.14 kPa @ 20 °C

Partition coefficient

Study results
  • 9 studies submitted
  • 7 studies processed
R Log Pow
2.2 - 6.5 @ -248.15 - 25 °C and pH 6.2 - 7 [7]

Type of Study provided
Studies with data
Key study 7
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
5.84 @ 20 °C

Water solubility

Study results
  • 6 studies submitted
  • 6 studies processed
R Water solubility (mass/vol.)
25 - 600 mg/L @ 20 °C and pH 5.2 - 9.1 [5]
R Water solubility (vol%)
0.1 - 0.7 vol% @ 20 °C and pH 6.4 [2]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
290 mg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
71.1 mN/m @ 243 mg/L

Flash point

Study results
  • 7 studies submitted
  • 7 studies processed
R Flash point
-30 - 43 °C @ 101.3 kPa [9]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
7.4 °C

Auto flammability

Study results
  • 6 studies submitted
  • 6 studies processed
R Autoflammability / self-ignition
401 - 502 °C @ 101.3 kPa [6]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
429 °C

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 7 studies submitted
  • 6 studies processed
R dynamic viscosity (in mPa s)
0.45 - 0.95 [10]
R kinematic viscosity (in mm²/s)
0.54 - 1.5 [13]

Type of Study provided
Studies with data
Key study 6
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
0.723 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
1 112

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air Hazard related to composition of atmosphere identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 1 mg/L [1]
LL50 (4 days) 1.1 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 1.2 - 2.7 mg/L [2]
EL50 (48 h) 1.2 - 3.3 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (4 days) 910 - 1 800 µg/L [4]
EC50 (72 h) 1.3 - 2 mg/L [2]
NOEC (4 days) 120 µg/L [1]
EL50 (4 days) 1.2 - 2.2 mg/L [4]
EL50 (72 h) 1.5 - 2.3 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 3.25 mg/m³ carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 23.4 mg/kg bw/day carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 3.25 µg/m³ carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 464 ng/kg bw/day carcinogenicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 5 1
Supporting study 6 2
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal absorption
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study 3 3
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
Low bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 1 %
Inhalation: 50 %

Acute toxicity

Study results
oral
  • 8 studies submitted
  • 8 studies processed
P/RResults
LD50 512 - 6 631 mg/kg bw (rat) [10]
LD50 5 251 - 5 627 mg/kg bw (mouse) [2]
M/CInterpretations of results
Practically nontoxic [1]

Type of Study provided
oral
Studies with data
Key study 8
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 9 studies submitted
  • 9 studies processed
P/RResults
LC50 (6 h) 1.723 mg/L air (rat) [1]
LC50 (6 h) 284 - 353 ppm (rat) [2]
LC50 (4 h) 5.14 - 43.767 mg/L air (rat) [6]
LC50 (4 h) 5 922 - 13 700 ppm (rat) [6]
LC50 (6 h) 738.5 mg/m³ air (mouse) [1]
M/CInterpretations of results
Toxic [2]

inhalation
Studies with data
Key study 8 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 7 studies submitted
  • 7 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
LD50 2 000 - 12 126 mg/kg bw (rabbit) [4]
LD50 5 000 mL/kg bw (rabbit) [1]
M/CInterpretations of results
Practically nontoxic [2]

dermal
Studies with data
Key study 6
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 20 000 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2 5
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: eye
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 3 1
Supporting study
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 4
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 12 studies submitted
  • 8 studies processed
P/RResults
NOAEL (rat): 4 - 625 mg/kg bw/day [9]
NOAEL (mouse): 625 mg/kg bw/day [1]
LOAEL (rat): 25 - 1 250 mg/kg bw/day [4]
LOAEL (mouse): 1 250 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 6 2
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: inhalation
  • 15 studies submitted
  • 13 studies processed
P/RResults
NOAEC (rat): 96 - 2 355 mg/m³ air [3]
NOAEC (rat): 30 - 7 000 ppm [12]
NOAEC (mouse): 32 - 96 mg/m³ air [2]
NOAEC (mouse): 5 - 2 000 ppm [5]
LOAEC (rat): 2.261 - 4.71 mg/L air [2]

Study data: inhalation
Studies with data
Key study 11 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed LOAEL 25 mg/kg bw/day (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 18 4
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 13 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 4 7
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVivo
Adverse effect observed (positive)

Carcinogenicity

Study results
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 7 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LOAEL 25 mg/kg bw/day (chronic, rat)
Inhalation route:
Adverse effect observed LOAEC 960 mg/m³ (chronic, mouse)

Toxicity to reproduction

Study results
Study data: reproduction
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 6 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 11 3
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Study results
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 4 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant