Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
295-302-4
CAS no.:
91995-41-4
Index number:
649-381-00-0
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Organic
Registered compositions:
7
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic to aquatic life with long lasting effects, is toxic if swallowed, is toxic in contact with skin, is very toxic to aquatic life, causes damage to organs through prolonged or repeated exposure, is toxic if inhaled, is an extremely flammable liquid and vapour, causes serious eye irritation, is suspected of damaging fertility or the unborn child, is suspected of causing cancer, may cause drowsiness or dizziness, causes skin irritation and may cause respiratory irritation.

Breakdown of all 37 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Aquatic Chronic 2 H411
STOT SE 3 H336
Eye Irrit. 2 H319
Skin Irrit. 2 H315
STOT SE 3 H335
Acute Tox. 4 H302
Muta. 1B H340 Harmonised Classification
Acute Tox. 4 H312
Repr. 2 H361
Flam. Liq. 1 H224
Carc. 1A H350
Carc. 1B H350 Harmonised Classification
Flam. Liq. 2 H225
Aquatic Acute 1 H400
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (91.89% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is broad agreement in that a majority of data submitters agree this substance is Mutagenic (75.68% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 4 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

This substance is used by consumers, in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, for thermoplastic manufacture, in processing aids at industrial sites and manufacturing of the substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, formulation of mixtures, formulation in materials, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; take actions to prevent static discharges; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; avoid release to the environment.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. Collect spillage. Do not induce vomiting.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ExxonMobil Chemical France SARL, 20 Rue Paul Heroult 92000 Nanterre France
  • RSI ChemRep Europe Ltd (K003), 27-30 Merchants Quay Merchants House 8 Dublin Ireland
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 MC-SQUARE Offices B-1831 Diegem Belgium
  • versalis S.p.A., P.zza Boldrini 1 20097 San Donato Milanese MILANO Italy

Substance names and other identifiers

[A complex combination of hydrocarbons obtained by distillation of heat-soaked steam-cracked naphtha. It consists predominantly of hydrocarbons having carbon numbers in the range of C4 through C6, predominantly C5.]
A complex combination of hydrocarbons obtained by distillation of heat-soaked steam-cracked naphtha. It consists predominantly of hydrocarbons having carbon numbers in the range of C4 through C6, predominantly C5.
C&L Inventory
Distillates (petroleum), heat-soaked steam-cracked naphtha, C5-rich
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures
Distillates (petroleum), heat-soaked steam-cracked naphtha, C5-rich
A complex combination of hydrocarbons obtained by distillation of heat-soaked steam-cracked naphtha. It consists predominantly of hydrocarbons having carbon numbers in the range of C4 through C6, predominantly C5.
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures
Distillates (petroleum), heat-soaked steam-cracked naphtha, C5-rich; Low boiling point naphtha — unspecified [ complex combination of hydrocarbons obtained by distillation of heat-soaked steam- cracked naphtha. It consists predominantly of hydrocarbons having carbon numbers in the range of C4 through C6, predominantly C5.]
A complex combination of hydrocarbons obtained by distillation of heat-soaked steam-cracked naphtha. It consists predominantly of hydrocarbons having carbon numbers in the range of C4 through C6, predominantly C5.
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Distillates (petroleum), heat-soaked steam-cracked naphtha, C5-rich; Low boiling point naphtha — unspecified
A complex combination of hydrocarbons obtained by distillation of heat-soaked steam-cracked naphtha. It consists predominantly of hydrocarbons having carbon numbers in the range of C4 through C6, predominantly C5.
FCM Active and Intelligent Materials - CMRs not allowed for use, Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
Low boiling point naphtha - unspecified
A complex combination of hydrocarbons obtained by distillation of heat-soaked steam-cracked naphtha. It consists predominantly of hydrocarbons having carbon numbers in the range of C4 through C6, predominantly C5.
C&L Inventory
Low boiling point naphtha — unspecified
A complex combination of hydrocarbons obtained by distillation of heat-soaked steam-cracked naphtha. It consists predominantly of hydrocarbons having carbon numbers in the range of C4 through C6, predominantly C5.
EU Ecolabels - Restrictions for Hazardous Substances/Mixtures
(Keerulise koostisega süsivesinike segu, mis saadakse kuumal temperatuuril töödeldud aurkrakitud raskbensiini destillatsioonil. Koosneb peamiselt süsivesinikest, mille süsiniku aatomite arv on vahemikus C4 kuni C6, valdavalt C5.] (et)
C&L Inventory
(Složeni sastav ugljikovodika dobiven destilacijom parno krekiranog benzina koji je podvrgnut toplinskoj apsorpciji. Sastoji se pretežito od ugljikovodika koji imaju broj ugljikovih atoma u području od C4 do C6, pretežito C5.) (hr)
C&L Inventory
[Kompleks blanding av hydrokarboner dannet ved destillasjon av varmebehandlet, dampkrakket nafta. Består for det meste av hydrokarboner, C4 til C6, hovedsakelig C5.] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov dobljena z destilacijo s pregreto paro krekirane nafte. Sestoji pretežno iz ogljikovodikov s številom ogljikovih atomov med C4 in C6, pretežno C5.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen, erhalten durch Destillation von dampfgekracktem Naphtha nach Wärmeaufnahme; besteht vorwiegend aus Kohlenwasserstoffen mit Kohlenstoffzahlen im Bereich von C4 bis C6, hauptsächlich C5] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná destiláciou z produktu parného krakovania ťažkého benzínu. Pozostáva predovšetkým z uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C4 do C6, predovšetkým C5.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi obţinută prin distilarea fracţiei nafta cracată cu vapori impregnată termic. Constă cu precădere în hidrocarburi având numărul de atomi de carbon cuprins între C4 şi C6, predominând C5.] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts, destilējot tvaika kamerā uzkarsētu tvaika krekinga ligroīnu. Sastāv pārsvarā no ogļūdeņražiem ar oglekļa atomu skaitu no C4 līdz C6, galvenokārt C5.] (lv)
C&L Inventory
[Složitá směs uhlovodíků získaná destilací pyrolyzního benzínu z tepelného reaktoru. Je složena převážně z uhlovodíků s počtem uhlíkových atomů v rozmezí C4 až C6, převážně C5.] (cs)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas distiliuojant šildomą krekingo vandens garais pirminį benziną. Jį sudaro daugiausia angliavandeniliai, turintys anglies atomų skaičių nuo C4 iki C6, daugiausia C5.] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet melegen szikkasztott gőzkrakkolt benzin desztillációjával nyernek. Főleg szénhidrogénekből áll, melyek szénatomszáma a C4-C6 tartományban van, elsősorban C5.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που λαμβάνεται με απόσταξη ατμοπυρολυμένης με παρατεταμένη θέρμανση νάφθας. Συνίσταται κυρίως από υδρογονάνθρακες με αριθμό ατόμων άνθρακα κυρίως μεταξύ C4 και C6, κυρίως C5.] (el)
C&L Inventory
[Комплексна комбинация от въглеводороди, получена при дестилацията на бензин от термичен процес (heat soaking) на паров крекинг. Състои се основно от въглеводороди с брой на въглеродните атоми в интервала от C4 до C6, включително, преобладаващо C5.] (bg)
C&L Inventory
Alacsony forráspontú benzin – nem meghatározott (hu)
C&L Inventory
combinación compleja de hidrocarburos obtenida por destilación de nafta craqueada a vapor impregnada con calor; compuesta fundamentalmente de hidrocarburos con un número de carbonos dentro del intervalo de C4 a C6, en su mayor parte C5 (es)
C&L Inventory
Combinaison complexe d'hydrocarbures obtenue par distillation de naphta ayant subi vapocraquage et maturation. Se compose principalement d'hydrocarbures dont le nombre de carbones se situe dans la gamme C4-C6, surtout en C5. (fr)
C&L Inventory
Combinazione complessa di idrocarburi prodotta per distillazione di nafta di steam cracking e a immersione di calore. È costituita in prevalenza da idrocarburi con un numero di atomi di carbonio prevalentemente nell'intervallo C4-6, soprattutto C5. (it)
C&L Inventory
Combinação complexa de hidrocarbonetos obtida por destilação de nafta aquecida e sujeita a steam cracking. É constituída predominantemente por hidrocarbonetos com número de átomos de carbono na gama C4 a C6, com predominância dos C5. (pt)
C&L Inventory
Destilados (petróleo), de nafta aquecida e sujeita a steam cracking, ricos em C5 (pt)
C&L Inventory
destilados (petróleo), nafta craqueada a vapor impregnada con calor, rica en C5 (es)
C&L Inventory
Destilati (nafta), parom krekirani benzin izložen produženom toplinskom djelovanju, s C5 bogat (hr)
C&L Inventory
destilati (zemeljsko olje), s pregreto paro krekirana nafta, bogata s C5; (sl)
C&L Inventory
Destillaadid (nafta), kuumas aurkrakitud raskbensiin, C5-rikas (et)
C&L Inventory
Destillat (petroleum), värmebehandlad ångkrackad nafta, C5-rika (sv)
C&L Inventory
Destillate (Erdöl), Wärme-Soaker dampfgekracktes Naphtha, C5-reich (de)
C&L Inventory
Destillaten (aardolie), hitteverzadigde stoomgekraakte nafta, rijk aan C5 (nl)
C&L Inventory
destillater (petroleum), varmebehandlet dampkrakket nafta, C5-rike (no)
C&L Inventory
destillater (råolie), varmeudblødt dampkrakket naphtha, C5-rige (da)
C&L Inventory
Destiláty (ropné), pyrolyzní benzín z tepelného reaktoru bohatý na C5; (cs)
C&L Inventory
destiláty (ropné), z parného krakovania ťažkého benzínu, s vysokým obsahom C5 (sk)
C&L Inventory
Destilāti (nafta), tvaika kamerā uzkarsēts tvaika krekinga ligroīns, satur daudz C5 (lv)
C&L Inventory
Destylaty wygrzewanej frakcji naftowej bogate w węglowodory C5 (ropa naftowa) (pl)
C&L Inventory
Desztillátumok (nyersolaj), melegen szikkasztott gőzkrakkolt benzin, C5-ben gazdag (hu)
C&L Inventory
Distilate (petrol), fracţia nafta impregnată termic, cracată cu vapori, bogată în C5 (mt)
C&L Inventory
Distilate (petrol), fracţia nafta impregnată termic, cracată cu vapori, bogată în C5 (ro)
C&L Inventory
Distiliatai (nafta), šildomasis krekingo vandens garais pirminio benzino distiliavimas, turi daug C5 (lt)
C&L Inventory
distillati (petrolio), nafta di steam cracking a bagno di calore, ricchi di C5 (it)
C&L Inventory
Distillats riches en C5 (pétrole), vapocraquage et maturation de naphta;naphta à bas point d'ébullition — non spécifié;[combinaison complexe d'hydrocarbures obtenue par distillation d'un naphta ayant subi vapocraquage et maturation. Se compose principalement d'hydrocarbures comportant entre 4 et 6 atomes de carbones (C4-C6), principalement des hydrocarbures en C5.] (fr)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen door destillatie van hitteverzadigde stoomgekraakte nafta. Bestaat voornamelijk uit koolwaterstoffen, C4 tot en met C6, overwegend C5. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider opnået ved destillation af varmeudblødt dampkrakket naphtha. Den består overvejende af carbonhydrider, C4 til og med C6, overvejende C5. (da)
C&L Inventory
Fracţia nafta cu punct de fierbere la temperaturi scăzute - nespecificat (mt)
C&L Inventory
Fracţia nafta cu punct de fierbere la temperaturi scăzute - nespecificat (ro)
C&L Inventory
Komplex blandning av kolväten, erhållen genom destillation av värmebehandlad ångkrackad nafta. Består främst av kolväten, i synnerhet C4 till C6, främst C5. (sv)
C&L Inventory
Lavtkogende uspecificeret nafta (da)
C&L Inventory
lavtkokende nafta - uspesifisert (no)
C&L Inventory
Ligroīns ar zemu viršanas temperatūru – nestandarta (lv)
C&L Inventory
Lågkokande nafta – ospecificerad (sv)
C&L Inventory
Madala keemispunktiga raskbensiin – määratlemata (et)
C&L Inventory
Matalalla kiehuva teollisuusbensiini – täsmentämätön (fi)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu tislaamalla vakiolämpötilassa pidettyä höyrykrakattua teollisuusbensiiniä. Koostuu pääasiassa hiilivedyistä, joiden hiililuku on välillä C4:stä C6:een, pääasiassa C5. (fi)
C&L Inventory
nafta con basso punto di ebollizione - non specificata (it)
C&L Inventory
Nafta de baixo ponto de ebulição - não especificada (pt)
C&L Inventory
nafta de bajo punto de ebullición, sin especificar (es)
C&L Inventory
Nafta met laag kookpunt - niet gespecifieerd (nl)
C&L Inventory
nafta z nizkim vreliščem – neopredeljeno (sl)
C&L Inventory
naphta à point d'ébullition bas - non spécifié (fr)
C&L Inventory
Naphtha, niedrigsiedend, nicht spezifiziert (de)
C&L Inventory
Nisko-vrijući benzin - nespecificiran (hr)
C&L Inventory
Niskowrząca benzyna - niespecyfikowana (pl)
C&L Inventory
Nízkovroucí benzínová frakce – nespecifikovaná (cs)
C&L Inventory
O combinaţie complexă de hidrocarburi obţinută prin distilarea fracţiei nafta cracată cu vapori impregnată termic. Constă cu precădere în hidrocarburi având numărul de atomi de carbon cuprins între C4 şi C6, predominând C5. (mt)
C&L Inventory
Tisleet (maaöljy), vakiolämpökäsitelty höyrykrakattu teollisuusbensiini, C5-rikas (fi)
C&L Inventory
Złożona mieszanina węglowodorów otrzymana przez destylację wygrzewanej temperaturowo krakingowanej parowo nafty. Składa się głównie z węglowodorów o liczbie atomów węgla zasadniczo w zakresie C4 do C6, głównie C5. (pl)
C&L Inventory
ťažký benzín s nízkou teplotou varu - nešpecifikovaný (sk)
C&L Inventory
Žematemperatūris pirminis benzinas – neapibrėžtas (lt)
C&L Inventory
αποστάγματαΑποστάγματα (πετρελαίου), νάφθας ατμοπυρολυμένης με παρατεταμένη θέρμανση, πλούσια σε C5 (el)
C&L Inventory
Νάφθα χαμηλού σημείου ζέσεως - μη προσδιοριζόμενη (el)
C&L Inventory
Дестилати (нефт), нискооктанов бензин от термичен процес (heat soaking) на паров крекинг, богати на C5 (bg)
C&L Inventory
Нискооктанов бензин с ниска температура на кипене-неспецифициран (bg)
C&L Inventory
Distillates (petroleum), heat-soaked steam-cracked naphtha, C5-rich
Other
Distillates (petroleum), heat-soaked steam-cracked naphtha, C5-rich
Registration dossier
Distillates (petroleum), heat-soaked steam-cracked naphtha, C5-rich
Registration dossier
Distillates(petroleum),heat-soaked steam-cracked naphtha, C5-rich
Registration dossier
not applicable
Registration dossier
not applicable
Registration dossier
649-381-00-0
Index number
C&L Inventory
91995-41-4
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 5 studies submitted
  • 5 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [5]
C Form
Other (100%) [2]
C Odour
Other (40%), Faint (20%), Slight (20%), Sweetish (20%) [5]
C Substance type
Organic (60%), Petroleum product (40%) [5]

Type of Study provided
Studies with data
Key study 3 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 3 studies processed
R Melting / freezing point
-100 - -65 °C @ 101.3 kPa [3]

Type of Study provided
Studies with data
Key study 1 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Melting / freezing point at 101 325 Pa
-100 - 32.2 °C

Boiling point

Study results
  • 5 studies submitted
  • 3 studies processed
R Boiling point
25 - 56.5 °C @ 101.3 kPa [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Boiling point at 101 325 Pa
46.25 - 172.2 °C

Density

Study results
  • 3 studies submitted
  • 2 studies processed
R Relative density
0.67 - 670.7 @ 15 - 20 °C [2]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 2 summaries processed
Relative density at 20°C
0.876 - 0.98

Vapour pressure

Study results
  • 6 studies submitted
  • 3 studies processed
R Vapour pressure
30.03 - 101.86 kPa @ 5.45 - 36.44 °C [10]

Type of Study provided
Studies with data
Key study 2 1
Supporting study 1 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Vapour pressure
1.86 - 450 hPa @ 20 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 2 studies processed
R Log Pow
2.2 - 5 @ 21 - 23 °C and pH 7 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Log Kow (Log Pow)
2.13 - 3.2 @ 20 °C

Water solubility

Study results
  • 2 studies submitted
  • 2 studies processed
R Water solubility (mass/vol.)
200 - 718 mg/L @ 20 °C and pH 6.26 - 6.9 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Water solubility
20 - 1 880 mg/L @ 20 - 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
71.7 mN/m @ 180 mg/L

Flash point

Study results
  • 2 studies submitted
  • 2 studies processed
R Flash point
-40 - -30 °C @ 101.3 - 102.6 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
-40 °C

Auto flammability

Study results
  • 3 studies submitted
  • 3 studies processed
R Autoflammability / self-ignition
285 - 315 °C @ 101.3 - 102.5 kPa [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
315 °C

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 2 studies submitted
  • 2 studies processed
R dynamic viscosity (in mPa s)
0.24 - 0.29 [2]
R kinematic viscosity (in mm²/s)
0.36 - 0.507 [3]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Static viscosity at 20 °C
0.51 mm²/s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 6 studies submitted
  • 2 studies processed
C Interpretation of results
Readily biodegradable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence 2
Other
Data waiving
no waivers
C Summaries
  • 4 summaries submitted
  • 4 summaries processed
Biodegradation in water
Readily biodegradable (50%), Under test conditions no biodegradation observed (50%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 3
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air Hazard related to composition of atmosphere identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning No data available: testing technically not feasible (1)

Short–term toxicity to fish

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 8.41 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (48 h) 4.7 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 12.4 - 18.9 mg/L [2]
NOEC (72 h) 6.47 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.31 mg/m³ repeated dose toxicity
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: (DNEL) 2.31 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 160.23 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 950 µg/kg bw/day repeated dose toxicity
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 690 µg/m³ repeated dose toxicity
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
Local Effects
Long-term: (DNEL) 690 µg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 143.5 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 280 µg/kg bw/day repeated dose toxicity
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
Local Effects
Long-term: Hazard unknown (no further information necessary as no exposure expected)
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 30 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 25.6 mg/kg bw/day acute toxicity
EYE Exposure
Low hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 4 1
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal absorption
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 0.1 %
Inhalation: 50 %

Acute toxicity

Study results
oral
  • 8 studies submitted
  • 8 studies processed
P/RResults
LD50 512 - 5 580 mg/kg bw (rat) [9]
LD50 1 - 4 mL/kg bw (rat) [2]
M/CInterpretations of results
Category 5 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 5 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 7 studies submitted
  • 6 studies processed
P/RResults
LC50 (6 h) 1.723 mg/L air (rat) [1]
LC50 (6 h) 284 - 353 ppm (rat) [2]
LC50 (4 h) 5.2 - 43.767 mg/L air (rat) [5]
LC50 (4 h) 13 700 ppm (rat) [1]
LC50 (6 h) 738.5 mg/m³ air (mouse) [1]
M/CInterpretations of results
Toxic [3]

inhalation
Studies with data
Key study 5 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 6 studies submitted
  • 6 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
LD50 3.03 mL/kg bw (rat) [1]
LD50 1 183 - 5 000 mg/kg bw (rabbit) [3]
LD50 1.59 mL/kg bw (rabbit) [2]
M/CInterpretations of results
Practically nontoxic [2]

dermal
Studies with data
Key study 5 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Oral route:
Adverse effect observed LD50 590 mg/kg bw
Inhalation route:
Adverse effect observed LC50 1 972 mg/m³
Dermal route:
No adverse effect observed LD50 8 260 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 4 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 5
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 8 studies submitted
  • 6 studies processed
P/RResults
NOAEL (rat): 4 - 625 mg/kg bw/day [6]
NOAEL (mouse): 625 mg/kg bw/day [1]
LOAEL (rat): 25 - 1 250 mg/kg bw/day [4]
LOAEL (mouse): 1 250 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 3 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: inhalation
  • 18 studies submitted
  • 17 studies processed
P/RResults
NOAEC (rat): 96 - 19 503 mg/m³ air [5]
NOAEC (rat): 30 - 1 139 ppm [9]
NOAEC (mouse): 28 - 613 mg/m³ air [4]
NOAEC (mouse): 5 - 30 ppm [3]
LOAEC (rat): 2.261 - 19.503 mg/L air [3]

Study data: inhalation
Studies with data
Key study 14 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Oral route - systemic effects:
Adverse effect observed NOAEL 4 mg/kg bw/day (subacute, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 27.6 mg/m³ (subchronic, mouse)
Inhalation route - local effects:
Adverse effect observed NOAEC 27.6 mg/m³ (subchronic, mouse)

Genetic toxicity

Study results
Study data: in vitro
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 16 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 26 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 13 10
Supporting study 2 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Toxicity - InVivo
Adverse effect observed (positive)

Carcinogenicity

Study results
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 3 5
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Oral route:
Adverse effect observed LOAEL 25 mg/kg bw/day (chronic, mouse)
Inhalation route:
Adverse effect observed LOAEC 960 mg/m³ (subchronic, mouse)

Toxicity to reproduction

Study results
Study data: reproduction
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 8 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Study data: developmental
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 10 2
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 60 mg/kg bw/day (subacute, rat)

Neurotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant