Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
271-727-0
CAS no.:
68606-11-1
Index number:
649-270-00-7
Molecular formula:
C26H62
SMILES:
CCCC.CCCCC.CCC(C)C.CCCCCC.CCCC(C)C
InChI:
InChI=1S/2C6H14.2C5H12.C4H10/c1-4-5-6(2)3;1-3-5-6-4-2;1-4-5(2)3;1-3-5-4-2;1-3-4-2/h6H,4-5H2,1-3H3;3-6H2,1-2H3;5H,4H2,1-3H3;3-5H2,1-2H3;3-4H2,1-2H3
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
16
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic to aquatic life with long lasting effects, is an extremely flammable liquid and vapour, is suspected of damaging fertility or the unborn child, causes skin irritation and may cause drowsiness or dizziness.

Breakdown of all 70 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Aquatic Chronic 2 H411
Skin Irrit. 2 H315
STOT SE 3 H336
Muta. 1B H340 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Repr. 2 H361
Flam. Liq. 1 H224
Flam. Liq. 2 H225
Flam. Liq. 3 H226
STOT RE 2 H373
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (62.5% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is broad agreement in that a majority of data submitters agree this substance is Mutagenic (62.5% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 8 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels, air care products, anti-freeze products, coating products, lubricants and greases, washing & cleaning products and welding & soldering products.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and of substances in closed systems with minimal release.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, of substances in closed systems with minimal release, manufacturing of the substance and formulation of mixtures.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, laboratory work, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, as processing aid, formulation of mixtures, formulation in materials, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; obtain special instructions before use; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. Do not induce vomiting.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • api raffineria di Ancona S.p.A., via Flaminia 685 60015 Falconara Marittima (AN) Italy
  • AS Novotrade Invest, Keemia vkt.1C 30328 Kohtla-Jarve Ida-Virumaa Estonia
  • Efremov Kautschuk GmbH, Alfred-Herrhausen- Allee 3-5 65760 Eschborn Germany
  • INA, d.d., Avenija V.Holjevca 10 p.p. 555 10002 Zagreb Croatia
  • LUKOIL Neftohim Burgas AD, Western Industrial Zone 8104 Bourgas Bulgaria
  • LUKOIL Neftohim Burgas AD (NNOS), Western Industrial Zone 8104 Burgas Bulgaria
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • SpetsInterProject Oy_ONOS, Näkinkaari 1 M 02320 Espoo Finland
  • ALMA PETROLI S.p.A., Via di Roma, 67 48121 RAVENNA Italy
  • International Petroleum Products (IPP)B.V., Herengracht 498 1017 CB Amsterdam Netherlands
  • ISAB S.r.l., ex S.s. 114 km 146 96010 Priolo Gargallo (SR) Sicily Italy
  • REACHLaw Ltd, Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • SGS EWACS NV 21, Keetberglaan 4 Haven 1091 9120 Melsele Antwerpen Belgium
  • SpetsInterProject Oy_KNPZ, Tekniikantie 21 02150 Espoo Finland
  • TAMOIL Raffinazione S.p.A, Piazzale Caduti del Lavoro, 30 26100 Cremona Italy

Substance names and other identifiers

[A complex combination of hydrocarbons produced from the topping plant by the distillation of crude oil. It boils in the range of approximately 36.1°C to 193.3°C (97°F to 380°F).]
A complex combination of hydrocarbons produced from the topping plant by the distillation of crude oil. It boils in the range of approximately 36.1°C to 193.3°C (97°F to 380°F).
C&L Inventory
Gasoline, straight-run, topping-plant
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Gasoline, straight-run, topping-plant
A complex combination of hydrocarbons produced from the topping plant by the distillation of crude oil. It boils in the range of approximately 36.1°C to 193.3°C (97°F to 380°F).
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Gasoline, straight-run, topping-plant; Low boiling point naphtha [ complex combination of hydrocarbons produced from the topping plant by the distillation of crude oil. It boils in the range of approximately 36,1 °C to 193,3 °C (97°F to 380°F).]
A complex combination of hydrocarbons produced from the topping plant by the distillation of crude oil. It boils in the range of approximately 36.1°C to 193.3°C (97°F to 380°F).
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Gasoline, straight-run, topping-plant; Low boiling point naphtha
A complex combination of hydrocarbons produced from the topping plant by the distillation of crude oil. It boils in the range of approximately 36.1°C to 193.3°C (97°F to 380°F).
FCM Active and Intelligent Materials - CMRs not allowed for use, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
Low boiling point naphtha
A complex combination of hydrocarbons produced from the topping plant by the distillation of crude oil. It boils in the range of approximately 36.1°C to 193.3°C (97°F to 380°F).
C&L Inventory
Raw, straight run gasoline
A complex combination of hydrocarbons produced from the topping plant by the distillation of crude oil. It boils in the range of approximately 36.1°C to 193.3°C (97°F to 380°F).
Other
Topping plant straight run gasoline
A complex combination of hydrocarbons produced from the topping plant by the distillation of crude oil. It boils in the range of approximately 36.1°C to 193.3°C (97°F to 380°F).
Other
(Keerulise koostisega süsivesinike segu, mis tekib toorõli destillatsioonil kerge fraktsiooni destillatsiooniseadmest. Selle keemistemperatuur on vahemikus ligikaudu 36,1°C kuni 193,3 °C. (et)
C&L Inventory
(Složeni sastav ugljikovodika iz topping-postrojenja proizveden destilacijom sirove nafte. Vrije u području približno od 36,1 ºC do 193,3 ºC.) (hr)
C&L Inventory
[Kompleks blanding av hydrokarboner fremstilt fra toppanlegget ved destillasjon av råolje. Omtrentlig kokepunktsintervall fra 36,1 °C til 193,3 °C (97 °F til 380 °F).] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov pridobljena z destilacijo surovega olja na koloni za frakcioniranje. Vrelišče ima v območju približno med 36,1 °C in 193,3 °C.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen, hergestellt in der Toppanlage durch Destillation von Rohöl; siedet im Bereich von etwa 36,1 °C bis 193,3 °C] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná oddestilovaním ľahkých frakcií pri destilácii ropy. Má teplotu varu v rozmedzí približne od 36,1 °C do 193,3 °C.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi produsă prin distilarea ţiţeiului brut. Fierbe la temperaturi cuprinse între aproximativ 36,1°C şi 193,3°C (97°F şi 380°F).] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts, destilējot jēlnaftu vieglo frakciju atdestilēšanas iekārtā. Aptuvenā viršanas temperatūra no 36,1°C līdz 193,3°C (97°F līdz 380°F).] (lv)
C&L Inventory
[Složitá směs uhlovodíků produkovaná jednotkou atmosférické destilace ropy. Má rozmezí teploty varu přibližně 36,1 °C až 193,3 °C.] (cs)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas stabilizavimo įrenginyje, distiliuojant žalią naftą. Jo virimo temperatūra maždaug nuo 36,1 °C iki 193,3 °C (nuo 97 °F iki 380 °F).] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet nyersolaj desztillációjával a könnyűlepárlóból nyernek. Hozzávetőlegesen a 36,1°C-tól 193,3°C-ig (97°F-től 380°F-ig) terjedő tartományban forr.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που παράγεται από τη μονάδα ατμοσφαιρικής απόσταξης αργού πετρελαίου. Αποστάζει μεταξύ 36,1 °C και 193,3 °C περίπου.] (el)
C&L Inventory
[Комплексна комбинация от въглевдодороди, получена от инсталацията за отбензинване на суровия нефт при дестилация на суров нефт. Има температура на кипене приблизително в интервала от 36,1°C до 193,3°C (97°F до 380°F).] (bg)
C&L Inventory
Alacsony forráspontú benzin (hu)
C&L Inventory
Bensiin, otsedestillatsioon, kerge fraktsiooni destillatsiooniseade (et)
C&L Inventory
Bensiini, suoratisle, keveiden jakeiden käsittely-yksikkö (fi)
C&L Inventory
bensin, direktedestillert (straight-run), toppanlegg (no)
C&L Inventory
Bensin, straight-run, toppningsanläggnings- (sv)
C&L Inventory
Benzin, közvetlen lepárlású, könnyűlepárló (hu)
C&L Inventory
Benzin, primarni, atm. destilacija (hr)
C&L Inventory
benzin, straight-run topanlægs (da)
C&L Inventory
benzina, prima distillazione, da impianto di topping (it)
C&L Inventory
Benzinas, tiesioginio distiliavimo, stabilizavimo įrenginys (lt)
C&L Inventory
Benzine, direct door fractionering verkregen, aftopinrichting (nl)
C&L Inventory
Benzină, distilare directă, (mt)
C&L Inventory
Benzină, distilare directă, (ro)
C&L Inventory
Benzyna z węzłów stabilizacji destylacji zachowawczej (pl)
C&L Inventory
benzín s nízkou teplotou varu (sk)
C&L Inventory
benzín, primárny, po oddestilovaní ľahkých frakcií (sk)
C&L Inventory
Benzín, primární, jednotka atmosférické destilace (cs)
C&L Inventory
Benzīns, tiešā destilācija, vieglo frakciju atdestilēšanas iekārta (lv)
C&L Inventory
combinación compleja de hidrocarburos producida en la planta de destilación primaria por la destilación de petróleo crudo; con un intervalo de ebullición aproximado de 36,1 °C a 193,3 °C (es)
C&L Inventory
Combinaison complexe d'hydrocarbures produite par l'unité de fractionnement lors de la distillation du pétrole brut. Son point d'ébullition est compris approximativement entre 36,1°C et 193,3°C. (fr)
C&L Inventory
Combinazione complessa di idrocarburi prodotta dall'impianto di topping per distillazione del grezzo. Ha intervallo di ebollizione 36,1 °C - 193,3 °C ca. (da 97°F a 380°F). (it)
C&L Inventory
Combinação complexa de hidrocarbonetos proveniente da unidade de topping por destilação de petróleo bruto. Destila no intervalo aproximado de 36,1 °C a 193,3 °C. (pt)
C&L Inventory
Een complexe verzameling koolwaterstoffen, afkomstig uit de aftopinrichting bij de destillatie van ruwe olie. Heeft een kooktraject van ongeveer 36,1°C tot 193,3°C. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider fremstillet fra topanlægget ved destillation af råolie. Den har et kogeinterval omtrent fra 36,1 °C til 193,3 °C (97 ºF til 380 ºF). (da)
C&L Inventory
Essence de distillation directe, unité de fractionnement; naphta à bas point d'ébullition;[combinaison complexe d'hydrocarbures produite dans l'unité de fractionnement par distillation de pétrole brut. Son intervalle d'ébullition est compris approximativement entre 36,1 et 193,3 oC (entre 97 et 380 oF).] (fr)
C&L Inventory
Fracţia nafta cu puncte scăzute de fierbere (mt)
C&L Inventory
Fracţia nafta cu puncte scăzute de fierbere (ro)
C&L Inventory
Gasolina, de destilação directa, de unidade de topping (pt)
C&L Inventory
gasolina, fracción de primera destilación, planta de destilación primaria (es)
C&L Inventory
Komplex blandning av kolväten erhållen från toppningsanläggningen genom destillation av råolja. Ungefärligt kokpunktsintervall från 36,1 °C till 193,3 °C. (sv)
C&L Inventory
Lavtkogende nafta (da)
C&L Inventory
lavtkokende nafta (no)
C&L Inventory
Ligroīns ar zemu viršanas temperatūru (lv)
C&L Inventory
Lågkokande nafta (sv)
C&L Inventory
Madala keemispunktiga raskbensiin (et)
C&L Inventory
Matalalla kiehuva teollisuusbensiini (fi)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu keveiden tisleiden käsittely-yksiköstä tislaamalla raakaöljyä. Kiehuu likimäärin välillä 36,1°C:sta 193,3°C:een (97°F:sta 380°F:iin). (fi)
C&L Inventory
nafta con basso punto di ebollizione (it)
C&L Inventory
Nafta de baixo ponto de ebulição (pt)
C&L Inventory
nafta de bajo punto de ebullición (es)
C&L Inventory
Nafta met laag kookpunt (nl)
C&L Inventory
nafta z nizko temperaturo vrelišča (sl)
C&L Inventory
naphta à point d'ébullition bas (fr)
C&L Inventory
Naphtha, niedrigsiedend (de)
C&L Inventory
nencin, direktna destilacija, kolona za frakcioniranje (sl)
C&L Inventory
Nisko-vrijući teški benzin (hr)
C&L Inventory
Niskowrząca frakcja benzynowa (pl)
C&L Inventory
Nízkovroucí benzínová frakce (cs)
C&L Inventory
O combinaţie complexă de hidrocarburi produsă prin distilarea ţiţeiului brut. Fierbe la temperaturi cuprinse între aproximativ 36,1°C şi 193,3°C (97°F şi 380°F). (mt)
C&L Inventory
Straight-run-Benzin, Toppanlage (de)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana z węzłów stabilizacji destylacji ropy naftowej. Wrze w zakresie temp. od ok. 36,1°C do 193,3°C. (pl)
C&L Inventory
Žematemperatūris pirminis benzinas (lt)
C&L Inventory
βενζίνη, απευθείας απόσταγμα, μονάδας ατμοσφαιρικής απόσταξης (el)
C&L Inventory
Νάφθα χαμηλού σημείου ζέσεως (el)
C&L Inventory
Бензин, прякодестилатен, от инсталация за отбензинване на нефта (bg)
C&L Inventory
Нискооктанов бензин с ниска температура на кипене (bg)
C&L Inventory
Gasoline, straight-run, topping-plant
Other
2-methylbutane; 2-methylpentane; butane; hexane; pentane
Other
Gasoline straight-run
Registration dossier
Gasoline, straight-run, topping-plant
C&L Inventory, Registration dossier
Gasoline, straight-run, topping-plant
Registration dossier
Gasoline, straight-run, topping-plant;
C&L Inventory
Gasoline straight-run
Registration dossier
Naphtha
Registration dossier
Straight-run Gasoline Export
Registration dossier
Virgin naphtha
Registration dossier
Virgin naphtha - heavy
Registration dossier
Virgin naphtha - light
Registration dossier
Нискооктанов бензин
Registration dossier
Нискооктанов бензин - лек
Registration dossier
Нискооктанов бензин - тежък
Registration dossier
649-270-00-7
Index number
C&L Inventory
68606-11-1
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Form
Other (100%) [2]
C Substance type
Petroleum product (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 3 studies submitted
  • 1 study processed
R Melting / freezing point
-60 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 4 studies submitted
  • 2 studies processed
R Boiling point
-20 - 260 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
0.62 - 0.88 @ 15 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 2 studies submitted
  • 2 studies processed
R Vapour pressure
240 kPa @ 37.8 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 2 studies processed
R Flash point
-40 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 8 studies submitted
  • 3 studies processed
R Autoflammability / self-ignition
280 - 470 °C @ 101.3 - 101.325 kPa [3]

Type of Study provided
Studies with data
Key study 2 1
Supporting study 4 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Extremely flammable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 4 studies submitted
  • 2 studies processed
R kinematic viscosity (in mm²/s)
1 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 14 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 12
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Study results
  • 1 study submitted
  • 1 study processed
% Distribution in Media:
R Air 93.02 % [1]
R Water 5.83 % [1]
R Soil 0.34 % [1]
R Sediment 0.81 % [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning Insufficient hazard data available (further information necessary) (1)

Short–term toxicity to fish

Study results
  • 32 studies submitted
  • 4 studies processed
P/RResults
LL50 (4 days) 8.2 - 10 mg/L [4]

Type of Study provided
Studies with data
Key study 4
Supporting study 28
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
EL50 (21 days) 10 mg/L [2]
NOELR (21 days) 2.6 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 24 studies submitted
  • 2 studies processed
P/RResults
EL50 (48 h) 4.5 mg/L [2]
NOELR (48 h) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 22
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOELR (21 days) 2.6 - 16 mg/L [4]
EL50 (21 days) 10 - 40 mg/L [4]

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 32 studies submitted
  • 2 studies processed
P/RResults
EL50 (4 days) 3.7 mg/L [2]
EL50 (72 h) 3.1 mg/L [2]
NOELR (72 h) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 30
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (40 h) 15.41 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.9 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 286.4 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 837.5 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1 066.67 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 410 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 152 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 178.57 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 640 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 87 studies submitted
  • 2 studies processed
P/RResults
LD50 5 000 mg/kg bw (rat) [2]
M/CInterpretations of results
Not classified [2]

Type of Study provided
oral
Studies with data
Key study 1 1
Supporting study 45 40
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 79 studies submitted
  • 4 studies processed
M/CInterpretations of results
Not classified [4]

inhalation
Studies with data
Key study 3 1
Supporting study 36 39
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 89 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 1 1
Supporting study 44 43
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5 610 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 209 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study 116 90
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 90 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1 1
Supporting study 44 43
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 86 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study 42 41
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 5 4
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 44 studies submitted
  • 2 studies processed
P/RResults
NOAEC (rat): 9.84 - 20 mg/L air [3]

Study data: inhalation
Studies with data
Key study 3 1
Supporting study 19 21
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 102 studies submitted
  • 8 studies processed
P/RResults
NOAEL (rat): 375 - 3 750 mg/kg bw/day [2]
NOEL (rabbit): 200 - 2 000 mg/kg bw/day [14]

Study data: dermal
Studies with data
Key study 9 1
Supporting study 43 49
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 402 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 43 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2 3
Supporting study 19 18
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 28 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2 1
Supporting study 12 13
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1 2
Supporting study 12 9
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Inhalation route:
No adverse effect observed NOAEC 9 869 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2 1
Supporting study 2 3
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1 2
Supporting study 7 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Effect on fertility
Inhalation route:
No adverse effect observed NOAEC 20 000 mg/m³ (chronic, rat)
Effect on developmental toxicity
Dermal route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 23 900 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant