Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
270-737-2
CAS no.:
68477-54-3
Index number:
649-411-00-2
Molecular formula:
C27H28
SMILES:
C=CC1=CC=CC=C1.C1C=CC2=C1C=CC=C2.C1C=CC2C3CC(C=C3)C12
InChI:
InChI=1/C10H12.C9H8.C8H8/c1-2-9-7-4-5-8(6-7)10(9)3-1;1-2-5-9-7-3-6-8(9)4-1;1-2-8-6-4-3-5-7-8/h1-2,4-5,7-10H,3,6H2;1-6H,7H2;2-7H,1H2
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
52
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance may be fatal if swallowed and enters airways.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is very toxic to aquatic life with long lasting effects, is very toxic to aquatic life, may cause cancer, may cause genetic defects, is toxic if inhaled, causes damage to organs through prolonged or repeated exposure, causes serious eye irritation, is a flammable liquid and vapour, is harmful if swallowed, is suspected of damaging fertility or the unborn child, is suspected of causing cancer, causes skin irritation, may cause respiratory irritation and may cause drowsiness or dizziness.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is toxic to aquatic life with long lasting effects.

Breakdown of all 650 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Eye Irrit. 2 H319
Skin Irrit. 2 H315
Flam. Liq. 3 H226
Acute Tox. 4 H302
Muta. 1B H340
Aquatic Chronic 2 H411
Carc. 1A H350
Acute Tox. 4 H332
Aquatic Acute 1 H400
STOT SE 3 H335
Aquatic Chronic 1 H410
Carc. 1B H350
STOT SE 3 H336
Repr. 2 H361
https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (56.89% of REACH registrations).
  • M
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Mutagenic (47.31% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 38 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in products with material based on: rubber (e.g. tyres, shoes, toys).

This substance is used in the following products: fuels.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, in materials as fuel sources, with limited exposure to unburned product to be expected and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: coating products and polymers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers, batch processing in synthesis or formulation with opportunity for exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials, manufacturing of the substance, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance is used in the following products: coating products and polymers.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, for thermoplastic manufacture, as an intermediate step in further manufacturing of another substance (use of intermediates), manufacturing of the substance and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, closed batch processing in synthesis or formulation, laboratory work and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites and as processing aid.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; take actions to prevent static discharges; do not breathe the dust, fume, gas, mist, vapours or spray; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Take off contaminated clothing and wash it before reuse. If swallowed: immediately call a poison center or doctor/physician. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Collect spillage. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Do not induce vomiting. If on skin: wash with soap and water. Follow specific treatment (see label).

Storage statements

Store this substance locked up.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • BASF Antwerpen N.V., Haven 725, Scheldelaan 600 2040 Antwerpen 4 Antwerpen Belgium
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Bostik Nederland B.V., Zeggeveld #10 RP4705 Roosendaal Netherlands
  • Cambridge Environmental Assessments part of RSK ADAS Europe (Ireland) Ltd (CYM), Office Suite B, Bluebell Business Centre, Old Naas Road D12X V7K Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemservice S.A. (4T8L), 13, Fausermillen 6689 Mertert Luxembourg
  • CIE SpA, Palladio 20 20010 Cornaredo Milan Italy
  • Daschi Chemie B.V., Molendijk-Zuid 5482WZ Schijndel Netherlands
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • DOW OLEFINVERBUND GMBH, Strasse B 13 D-06258 Schkopau Germany
  • Eastman Chemical Middelburg B.V., Herculesweg 35 4338 PL Middelburg Netherlands
  • EURECAT FRANCE SAS, 121 ave Marie Curie ZI Jean Jaurès 07800 La Voulte sur Rhône France
  • ExxonMobil Chemical France SARL, 20 Rue Paul Heroult 92000 Nanterre France
  • Gazprom Marketing & Trading France 28, 68 Avenue des Champs Elysees 75008 Paris France
  • Glencore International Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
  • Henkel AG & Co. KGaA - Only Representative HCorpUSA, Henkelstrasse 67 40191 Duesseldorf Germany
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Knoell NL_OR_051, Agro Business Park 75 6708 PV Wageningen Netherlands
  • Koole Tankstorage Botlek B.V., Oude Maasweg 6 3197 KJ Rotterdam Netherlands
  • LUKOIL Neftohim Burgas AD (LNH Moscow Stav), Western Industrial Zone 8104 Bourgas Bulgaria
  • Luxcontrol S.A. (OR 60), 1, Avenue des Terres Rouges 4331 Esch-sur-Alzette Luxembourg
  • Penman Consulting bvba 17, Avenue des Arts 10 1210 Brussels Belgium
  • Rain Carbon Germany GmbH, Kekulestr. 30 44579 Castrop-Rauxel Germany
  • REACH COMPLIANCE SERVICES LIMITED, Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford, Dublin 18, Ireland Dublin 18 Dublin Ireland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • Resinall Rütgers Resins GmbH, Varziner Str. 49 D-47138 Duisberg Germany
  • Ricardo Nederland BV, Catharijnesingel 33 3511 GC Utrecht Netherlands
  • Rütgers Resins BV, Molenlaan 30 1422 ZA Uithoorn Netherlands
  • SABIC Petrochemicals B.V., Europaboulevard 1 6135 LD Sittard Limburg Netherlands
  • Savarè I.C. S.r.l., via Polidoro da Caravaggio 3 20156 Milano Lombardia Italy
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 MC-SQUARE Offices B-1831 Diegem Belgium
  • Sun Chemical B.V., Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands
  • Umicore Specialty Materials Brugge, Kleine Pathoekeweg 82 8000 Brugge Belgium
  • versalis S.p.A., P.zza Boldrini 1 20097 San Donato Milanese MILANO Italy
  • YD Star Netherlands B.V., Molendijk Zuid 23B 5482 WZ Schijndel Netherlands
  • Brewchem Trading, 24 Rodway Road Roehampton SW155DS London Grt London United Kingdom
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CRAY VALLEY SA OR8, 2 Place Jean Millier 92400 Courbevoie France
  • Fenchem Germany GmbH, Mathias-Brüggen-Straße 146 50829 Köln Germany
  • Interchem Logistics B.V., Javastraat 4 3016 CE Rotterdam Netherlands
  • LUKOIL Neftohim Burgas AD (LNH Moscow KNH), Western Industrial Zone 8104 Bourgas Bulgaria
  • Mardan BV, Postbus 30149 3001DC Rotterdam Netherlands
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • RÜTGERS Basic Aromatics GmbH, Kekulestr. 30 44579 Castrop-Rauxel Germany
  • VIBIPLAST s.r.l., Via Modigliani 12-19 20022 Castano Primo (MI) Italy

Substance names and other identifiers

(C8-C12) Partial fraction (petroleum)
A complex combination of organic compounds obtained by the distillation of products from a steam cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C8 through C12.
Other
[A complex combination of organic compounds obtained by the distillation of products from a steam cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C8 through C12.]
A complex combination of organic compounds obtained by the distillation of products from a steam cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C8 through C12.
C&L Inventory
Cracked kerosine
A complex combination of organic compounds obtained by the distillation of products from a steam cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C8 through C12.
C&L Inventory
Distillates (petroleum), steam-cracked, C8-12 fraction
EC Inventory, REACH pre-registration, Other
Distillates (petroleum), steam-cracked, C8-12 fraction
A complex combination of organic compounds obtained by the distillation of products from a steam cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C8 through C12.
C&L Inventory, REACH pre-registration, Other
Distillates (petroleum), steam-cracked, C8-12 fraction; Cracked kerosine [ complex combination of organic compounds obtained by the distillation of products from a steam cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C8 through C12.]
A complex combination of organic compounds obtained by the distillation of products from a steam cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C8 through C12.
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties
Distillates (petroleum), steam-cracked, C8-12 fraction; Cracked kerosine
A complex combination of organic compounds obtained by the distillation of products from a steam cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C8 through C12.
EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes
Distillates, petroleum, steam-cracked, C8-12 fraction
A complex combination of organic compounds obtained by the distillation of products from a steam cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C8 through C12.
Other
(Keerumise koostisega orgaanilised ühendid, mis saadakse arukrakkimisprotsessi produktide destilleerimisel. Koosneb peamiselt küllastumata süsivesinikest, mille süsiniku aatomite arv on valdavalt vahemikus C8 kuni C12.) (et)
C&L Inventory
(Složeni sastav organskih spojeva dobivena destilacijom produkata parnog krekinga. Sadrži pretežno nezasićene ugljikovodike koji imaju broj ugljikovih atoma pretežito u rasponu od C8 do C12.) (hr)
C&L Inventory
[Gőzkrakkolás termékének desztillációval kapott terméke. Főleg telítetlen szénhidrogéneket (C8-C12) tartalmaz.] (hu)
C&L Inventory
[Kompleks blanding av organiske forbindelser dannet ved destillasjon av produkter fra dampkrakking. Består for det meste av umettede hydrokarboner, hovedsakelig C8 til C12.] (no)
C&L Inventory
[Komplekss ogļūdeņražu savienojums, ko iegūst, destilējot destilātus bez vieglajām frakcijām pēc tvaika krekinga. Tajā pārsvarā ir nepiesātināti ogļūdeņraži, kuros oglekļa atomu skaits ir galvenokārt diapazonā no C8 līdz C12.] (lv)
C&L Inventory
[Komplexe Kombination organischer Verbindungen, erhalten durch Destillation von Produkten aus einem Dampf-Krackverfahren. Besteht vorherrschend aus ungesättigten Kohlenwasserstoffen mit Kohlenstoffzahlen vorherrschend im Bereich von C8 bis C12.] (de)
C&L Inventory
[Komplexná zmes organických zlúčenín získavaná destiláciou produktov z procesu parného krakovania. Pozostáva predovšetkým z nenasýtených uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C8 do C12.] (sk)
C&L Inventory
[O combinaţie complexă de compuşi organici obţinuta prin distilare de produse dintr-un proces cracare cu abur. Se compune în principal din hidrocarburi nesaturate cu număr de atomi de carbon predominant de la C8 la C12.] (ro)
C&L Inventory
[Složitá směs organických sloučenin získaná destilací produktů z pyrolyzního procesu. Je složena převážně z nenasycených uhlovodíků s počtem uhlíkových atomů převážně v rozmezí C8 až C12.] (cs)
C&L Inventory
[sudėtingas organinių junginių mišinys, gautas distiliuojant garų fazėje atliekamo krekingo produktus. Jame vyrauja nesotieji angliavandeniliai, kurių anglies atomų skaičius yra daugiausia tarp C8 ir C12.] (lt)
C&L Inventory
[Комплексна комбинация от въглеводороди, получена при дестилация на продукти от паров крекинг Състои се основно от ненаситени въглеводороди с с брой на въглеродните атоми преобладаващо в интервала от C8 до C12 включително.] (bg)
C&L Inventory
Cherosene da cracking (it)
C&L Inventory
Combinación compleja de compuestos orgánicos obtenida por destilación de productos de un proceso de craqueo a vapor. Compuesta fundamentalmente de hidrocarburos insaturados con un número de carbonos en su mayor parte dentro del intervalo de C8 a C12. (es)
C&L Inventory
Combinaison complexe de composés organiques obtenue par distillation des produits résultant d'un vapocraquage. Se compose principalement d'hydrocarbures insaturés dont le nombre de carbones se situe en majorité dans la gamme C8-C12. (fr)
C&L Inventory
Combinazione complessa di composti organici ottenuta per distillazione di prodotti provenienti da un processo di cracking con vapore. AE costituita prevalentemente da idrocarburi insaturi con numero di atomi di carbonio prevalentemente nell'intervallo C8-C12. (it)
C&L Inventory
destilados (petróleo), craqueados a vapor, fracción de C8-12 (es)
C&L Inventory
destilados (petróleo), do steam-cracking, fracçao C8-12 (pt)
C&L Inventory
Destilati (nafta), parom krekirani, C8-12 frakcija (hr)
C&L Inventory
Destilati (nafta), z vodno paro krekirani, C8–12 frakcija (sl)
C&L Inventory
Destillaadid (nafta), aurkrakitud, C8-12 fraktsioon (et)
C&L Inventory
destillat (petroleum), ångkrackade, C8-12-fraktion (sv)
C&L Inventory
Destillate (Erdöl), Dampf-gekrackt, C8-12-Fraktion (de)
C&L Inventory
destillaten (aardolie), stoomgekraakt, C8-12-fractie (nl)
C&L Inventory
destillater (petroleum), dampkrakkede, C8-12-fraksjon (no)
C&L Inventory
destillater (råolie), dampkrakkede, C8-12-fraktion (da)
C&L Inventory
Destiláty (ropa), pyrolyzované, frakce C8-12; (cs)
C&L Inventory
destiláty (ropné), frakcia C8-12, z parného krakovania (sk)
C&L Inventory
Destylaty (ropa naftowa), frakcja C8-12 z krakingu parowego (pl)
C&L Inventory
Distilate (petroliere), cracare cu abur, fracţia C8-12 (ro)
C&L Inventory
distiliatai (nafta), krekinguoti garų fazėje, C8-12 frakcija (lt)
C&L Inventory
distillati (petrolio), crackizzati a vapore, frazione C8-12 (it)
C&L Inventory
Distillats de vapocraquage (pétrole), fraction en C8-12;kérosène de craquage;[combinaison complexe de composés organiques obtenue par distillation des produits résultant d'un vapocraquage. Se compose principalement d'hydrocarbures insaturés comportant majoritairement entre 8 et 12 atomes de carbone (C8-C12).] (fr)
C&L Inventory
Een complexe verzameling organische verbindingen, verkregen door de destillatie van produkten van een stoomkraakproces. Bestaat voornamelvk uit onverzadigde koolwaterstoffen, overwegend C8 tot en met C12. (nl)
C&L Inventory
En sammensat blanding af organiske forbindelser opnået ved destillationen af produkter fra en dampkrakningsproces. Den består overvejende af umættende carbonhydrider, overvejende C8 til og med C12. (da)
C&L Inventory
Frakcja naftowa z krakowania (pl)
C&L Inventory
Gekraakte kerosine (nl)
C&L Inventory
Kerosen obtinut prin cracare (ro)
C&L Inventory
Kompleksna kombinacija organskih spojin dobljenaz destilacijo produktov iz procesa krekiranja s paro.Sestavljena je pretežno iz nenasičenih ogljikovodikov,ki imajo število ogljikov pretežno v območju odC8 do C12. (sl)
C&L Inventory
Krackkerosin (de)
C&L Inventory
Krakattu kerosiini (fi)
C&L Inventory
krakket parafin (no)
C&L Inventory
Krakket petroleum (da)
C&L Inventory
Krakkolt kerozin (hu)
C&L Inventory
Krakkpetrooleum (et)
C&L Inventory
krakovaný petrolej (sk)
C&L Inventory
Krakový petrolej (cs)
C&L Inventory
Krekiran kerozin (sl)
C&L Inventory
Krekirani petrolej (hr)
C&L Inventory
Kérosène de craquage (fr)
C&L Inventory
naftas destilāti bez vieglajām frakcijām pēc tvaika krekinga, C10-12 frakcija (lv)
C&L Inventory
petrolejas krekinga produkts (lv)
C&L Inventory
Párlatok (ásványolaj), gőzzel krakkolt ásványolaj desztillátum C8-C12 frakció (hu)
C&L Inventory
Queroseno craqueado (es)
C&L Inventory
Queroseno de cracking (pt)
C&L Inventory
Tisleet (maaöljy), höyrykrakatut, C8-12-fraktio (fi)
C&L Inventory
Uma combinação complexa de compostos organicos obtida pela destilação de produtos de um processo de steam-cracking. BE constituída predominantemente por hidrocarbonetos com números de átomos de carbono predominantemente na gama de C8 até C12. (pt)
C&L Inventory
Złożona mieszanina związków organicznych otrzymywana podczas destylacji produktów z procesu krakingu z parą wodną. Składa się przede wszystkim z nienasyconych węglowodorów o liczbie atomów węgla głównie w zakresie od C8 do C12 (pl)
C&L Inventory
žibalo krekingas (lt)
C&L Inventory
απόσταγμα (πετρελαίου), ατμοπυρολυμένα, κλάσμα C8-12 (el)
C&L Inventory
Κηεροξζίνη από διάσπαση (el)
C&L Inventory
Дестилати(нефт), от паров крекинг, C8-12 фракция (bg)
C&L Inventory
Крекиран керосин (bg)
C&L Inventory
Distillates (petroleum), steam-cracked, C8-12 fraction
Other
1H-indene; ethenylbenzene; tricyclo[5.2.1.0²,⁶]deca-3,8-diene
Registration dossier, Other
Benzene rectification still residue
Registration dossier
C9 resinfeed
Registration dossier
C9 resinfeed
Registration dossier
Distillates (petroleum), steam-cracked C8-12 fraction
Registration dossier
Distillates (petroleum), steam-cracked, C8-12 fraction
C&L Inventory, Registration dossier
Distillates (petroleum), steam-cracked, C8-12 fraction
Registration dossier
Distillates (petroleum), steam-cracked, C8-12 fraction DCPD Rich
Registration dossier
Distillates (petroleum), steam-cracked, C8-12 fraction DCPD Rich (Member of LOA Category L DCPD)
Registration dossier
Distillates (petroleum), steam-cracked, C8-12 fraction/Distillates (petroleum), steam-cracked, C8-12 fraction DCPD Rich (LOA Category L DCPD)
Registration dossier
Distillates (petroleum), steam-cracked, C8-C12 fraction
Registration dossier
Distillates(petroleum), steam-cracked, C8-12 fraction
Registration dossier
Distillates, petroleum, steam-cracked, C8-12 fraction
Registration dossier
Not applicable
Registration dossier
Resin Former Prime
Registration dossier
Resin Oil: Distillates (petroleum), steam-cracked, C8-12 fraction DCPD Rich
Registration dossier
Streaming C9
Registration dossier
Blend TN-200
Registration dossier
C9 resinfeed
Registration dossier
C9-Fraction unhydrogenated
Registration dossier
C9-FractionC10-FractionC8-C12-Fraction
Registration dossier
Distillates (petroleum), steam-cracked, C8-12 fraction
Registration dossier
Distillates (petroleum), steamcracked, C8-12 fraction
Registration dossier
Harzöl II
Registration dossier
Harzöl III
Registration dossier
Hydrocarbon resin
Registration dossier
Not applicable
Registration dossier
Polymer feed
Registration dossier
Resin Oil
Registration dossier
Resin oil II (Harzöl II)
Registration dossier
Resin oil III (Harzöl III)
Registration dossier
Velrez C9
Registration dossier
649-411-00-2
Index number
C&L Inventory
68477-54-3
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 15 studies submitted
  • 15 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [15]
C Form
Other (67%), Not specified (33%) [6]
C Odour
Characteristic of aromatic compounds (69%), Other (31%) [13]
C Substance type
Organic (69%), Petroleum product (15%), Other (15%) [13]

Type of Study provided
Studies with data
Key study 9 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 8 studies submitted
  • 7 studies processed
R Melting / freezing point
-30 - 45 °C [7]

Type of Study provided
Studies with data
Key study 8
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 3 summaries processed
Melting / freezing point at 101 325 Pa
4.8 - 32.2 °C

Boiling point

Study results
  • 26 studies submitted
  • 20 studies processed
R Boiling point
77 - 430.5 °C @ 101.3 - 101.325 kPa [20]

Type of Study provided
Studies with data
Key study 24 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 3 summaries processed
Boiling point at 101 325 Pa
80.09 - 182 °C

Density

Study results
  • 19 studies submitted
  • 4 studies processed
R Relative density
0.894 - 0.94 @ 15.556 - 20 °C [4]

Type of Study provided
Studies with data
Key study 19
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 3 summaries processed
Relative density at 20°C
0.876 - 0.98

Vapour pressure

Study results
  • 19 studies submitted
  • 13 studies processed
R Vapour pressure
2 - 41 hPa @ 20 - 100 °C [13]

Type of Study provided
Studies with data
Key study 19
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 3 summaries processed
Vapour pressure
1.86 - 100 hPa @ 20 °C

Partition coefficient

Study results
  • 6 studies submitted
  • 3 studies processed
R Log Pow
2.8 - 6.5 @ 25 °C [3]

Type of Study provided
Studies with data
Key study 4
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 3 summaries processed
Log Kow (Log Pow)
2.13 - 5.8 @ 20 °C

Water solubility

Study results
  • 7 studies submitted
  • 3 studies processed
R Water solubility (mass/vol.)
62 - 108 mg/L @ 20 °C [3]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 3 summaries processed
Water solubility
20 - 1 880 mg/L @ 20 - 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 10 studies submitted
  • 10 studies processed
R Flash point
36.5 - 76 °C @ 101.325 kPa [10]

Type of Study provided
Studies with data
Key study 10
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Flash point at 101 325 Pa
46.4 °C

Auto flammability

Study results
  • 4 studies submitted
  • 4 studies processed
R Autoflammability / self-ignition
409 - 505 °C [4]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
457 °C

Flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 15 studies submitted
  • 15 studies processed
R Other:
1.81 [2]
R dynamic viscosity (in mPa s)
2.39 [2]
R kinematic viscosity (in mm²/s)
0.95 - 3.033 [11]

Type of Study provided
Studies with data
Key study 15
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Static viscosity at 20 °C
1.6 mm²/s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 6 studies submitted
  • 3 studies processed
C Interpretation of results
Inherently biodegradable (67%), Not readily biodegradable (33%) [3]

Type of Study provided
Studies with data
Key study 4
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 4 summaries submitted
  • 3 summaries processed
Biodegradation in water
Under test conditions no biodegradation observed (67%), Readily biodegradable (33%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
162

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 1 µg/L (1)
Intermittent releases (freshwater) -
Marine water 1 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No hazard identified (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 9 studies submitted
  • 5 studies processed
P/RResults
LC50 (4 days) 580 - 6 100 µg/L [4]
LL50 (4 days) 730 - 7 300 µg/L [5]
LL50 (48 h) 9.9 mg/L [1]

Type of Study provided
Studies with data
Key study 5
Supporting study 2
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 4 studies processed
P/RResults
EC50 (48 h) 760 - 2 900 µg/L [4]
EC50 (24 h) 1.4 mg/L [2]
EL50 (48 h) 910 - 3 200 µg/L [4]
EL50 (24 h) 1.6 mg/L [2]

Type of Study provided
Studies with data
Key study 4
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 4 studies submitted
  • 4 studies processed
P/RResults
EC50 (4 days) 1 mg/L [1]
EC50 (72 h) 940 µg/L [1]
NOEC (4 days) 940 µg/L [2]
NOEC (72 h) 300 - 370 µg/L [4]
NOELR (4 days) 470 mg/L [2]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
EC50 for freshwater algae
1.3 mg/L
EC10 or NOEC for freshwater algae
460 µg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (56 days) 47.2 mg/L [1]
NOEC (28 days) 47.2 mg/L [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
47.2 mg/L

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 4 summaries submitted
  • 4 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.31 mg/m³ repeated dose toxicity
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: (DNEL) 2.31 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 160.23 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 340 µg/kg bw/day -
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 690 µg/m³ repeated dose toxicity
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
Local Effects
Long-term: (DNEL) 690 µg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 143.5 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 280 µg/kg bw/day repeated dose toxicity
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
Local Effects
Long-term: Hazard unknown (no further information necessary as no exposure expected)
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 30 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 25.6 mg/kg bw/day acute toxicity
EYE Exposure
Medium hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: dermal absorption
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 4 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 0.1 %
Inhalation: 50 %

Acute toxicity

Study results
oral
  • 11 studies submitted
  • 7 studies processed
P/RResults
LD50 512 - 5 000 mg/kg bw (rat) [9]
M/CInterpretations of results
Not classified [4]

Type of Study provided
oral
Studies with data
Key study 7
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 20 studies submitted
  • 8 studies processed
P/RResults
LC50 (6 h) 1.723 mg/L air (rat) [1]
LC50 (6 h) 284 - 353 ppm (rat) [2]
LC50 (4 h) 2.7 - 30 000 mg/m³ air (rat) [9]
M/CInterpretations of results
Not classified [4]

inhalation
Studies with data
Key study 7 1
Supporting study 9 3
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 9 studies submitted
  • 9 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [3]
LD50 2 000 mg/kg bw (rabbit) [6]
M/CInterpretations of results
Not classified [5]

dermal
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 4 summaries submitted
  • 2 summaries processed
Oral route:
Adverse effect observed LD50 590 mg/kg bw
Inhalation route:
Adverse effect observed LC50 1 972 mg/m³
Dermal route:
No adverse effect observed LD50 8 260 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 11 2
Supporting study 5 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 20 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 9
Supporting study 6 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 4 summaries submitted
  • 4 summaries processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 4 summaries submitted
  • 4 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 12 studies submitted
  • 9 studies processed
P/RResults
NOAEL (rat): 4 - 625 mg/kg bw/day [16]
LOAEL (rat): 25 - 1 250 mg/kg bw/day [6]

Type of Study provided
Study data: oral
Studies with data
Key study 7 2
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
Study data: inhalation
  • 7 studies submitted
  • 7 studies processed
P/RResults
NOAEC (rat): 96 - 2 355 mg/m³ air [6]
NOAEC (rat): 30 - 625 ppm [6]
NOAEC (mouse): 5.1 ppm [1]
LOAEC (rat): 4.71 mg/L air [2]
LOAEC (rat): 1 250 ppm [2]

Study data: inhalation
Studies with data
Key study 4 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 4 summaries submitted
  • 2 summaries processed
Oral route - systemic effects:
Adverse effect observed NOAEL 4 mg/kg bw/day (subacute, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 27.6 mg/m³ (subchronic, mouse)
Inhalation route - local effects:
Adverse effect observed NOAEC 27.6 mg/m³ (subchronic, mouse)

Genetic toxicity

Study results
Study data: in vitro
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 4 4
Supporting study 1 2
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 4 summaries submitted
  • 1 summary processed
Toxicity - InVivo
Adverse effect observed (positive)

Carcinogenicity

Study results
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 4 summaries submitted
  • 1 summary processed
Oral route:
Adverse effect observed LOAEL 25 mg/kg bw/day (chronic, mouse)
Inhalation route:
Adverse effect observed LOAEC 960 mg/m³ (subchronic, mouse)

Toxicity to reproduction

Study results
Study data: reproduction
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 4
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Study data: developmental
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1 1
Supporting study 4
Weight of evidence
Other 4
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 4 summaries submitted
  • 1 summary processed
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 60 mg/kg bw/day (subacute, rat)

Neurotoxicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant

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