Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
265-066-7
CAS no.:
64741-64-6
Index number:
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
22
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic to aquatic life with long lasting effects, is an extremely flammable liquid and vapour, is suspected of damaging fertility or the unborn child, causes skin irritation and may cause drowsiness or dizziness.

Breakdown of all 259 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Muta. 1B H340 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Aquatic Chronic 2 H411
Skin Irrit. 2 H315
STOT SE 3 H336
Flam. Liq. 1 H224
Repr. 2 H361
Flam. Liq. 2 H225
Flam. Liq. 3 H226
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (40% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Mutagenic (40% of REACH registrations).

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 28 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 000 - 10 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels, air care products, anti-freeze products, coating products, lubricants and greases, washing & cleaning products and welding & soldering products.

Other release to the environment of this substance is likely to occur from: outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and of substances in closed systems with minimal release.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: fuels.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, in materials as fuel sources, with limited exposure to unburned product to be expected, batch processing in synthesis or formulation with opportunity for exposure, roller or brushing applications, non-industrial spraying and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), indoor use as processing aid and outdoor use as processing aid.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), manufacturing of the substance, formulation of mixtures, of substances in closed systems with minimal release, as processing aid, in the production of articles, as processing aid, for thermoplastic manufacture and formulation in materials.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, laboratory work, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, as processing aid, formulation of mixtures, formulation in materials, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; obtain special instructions before use; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. Do not induce vomiting.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ENI, Piazzale Enrico Mattei 1 00144 Rome Italy
  • Essar Oil (UK) Limited, Stanlow Manufacturing Complex PO Box 3 CH65 4HB Ellesmere Port Cheshire United Kingdom
  • Esso Deutschland GmbH, Caffamacherreihe 5 20355 Hamburg Germany
  • ESSO Italiana Srl, Viale Castello della Magliana 25 00148 Roma Italy
  • Esso Petroleum Company Ltd., Ermyn Way ExxonMobil House KT22 8UX Surrey Leatherhead United Kingdom
  • Esso Raffinage S.A.S., 20 Rue Paul Heroult 92000 Nanterre France
  • Esso SAF, 20 Rue Paul Heroult 92000 Nanterre France
  • ExxonMobil Petroleum & Chemical BV, Polderdijkweg 2030 Antwerpen Belgium
  • HH Compliance Ltd., The Rubicon Centre, CIT Campus, 0000 Bishopstown, Cork Ireland
  • ISAB S.r.l., ex S.s. 114 km 146 96010 Priolo Gargallo (SR) Sicily Italy
  • J.P. Morgan Commodities Holdings IV B.V., Fred. Roeskestraat 123 1076 EE Amsterdam Netherlands
  • Noble Clean Fuels Limited, 33 Cavendish Square W1G 0PW London United Kingdom
  • OMV Downstream GmbH, Trabrennstraße 6-8 A-1020 Wien Austria
  • OMV PETROM S.A., 22 Coralilor Street (“Petrom City”) Sector 1 013329 Bucharest Romania
  • PCK RAFFINERIE GMBH, Passower Chaussee 111 16303 Schwedt/Oder Germany
  • PETROBRAS GLOBAL TRADING BV - PGT BV, Weena 762 - 9th Floor, First Rotterdam 3014 DA Rotterdam Netherlands
  • Petroleos del Norte, S.A., Ed. Muñatones, Bº San Martín, 5 48550 Muskiz Vizcaya Spain
  • Phillips 66 Limited, 7th Floor 200-202 Aldersgate Street EC1A 4HD London United Kingdom
  • Polski Koncern Naftowy ORLEN SA, ul. Chemików 7 09-411 Płock Poland
  • Repsol Petroleo, S.A., Calle Mendez Alvaro, 44 28045 Madrid Madrid Spain
  • RWE Supply & Trading GmbH, 60 Threadneedle Street EC2R 8HP London United Kingdom
  • Shell Trading International Ltd, Shell Centre SE1 7NA London United Kingdom
  • Shell Trading Rotterdam B. V., Weena 70 3012 CM Rotterdam Netherlands
  • SLOVNAFT, a.s., Vlcie hrdlo 1 824 12 Bratislava Slovakia
  • Sonatrach Raffineria Italiana S.r.l., Via Montenapoleone 29 20121 Milano Italy
  • Trafigura Ventures V.B.V., Evert van de Beekstraat 1-82 The Base, Tower B, 5th floor 1118 CL Schiphol Netherlands
  • Valero Energy Ltd, Pembroke Refinery SA71 5SJ Pembroke United Kingdom
  • Vitol Chemicals BV, K.P. van der Mandelelaan 130 3062 MB Rotterdam Netherlands
  • Borealis AG, Wagramerstrasse 17-19 1220 Wien Austria
  • Chevron BV M/I, Hofplein 33 3011AJ Rotterdam Netherlands
  • PETROBRAS EUROPE LIMITED., 9th Floor, 1 Angel Court EC2R 7HJ London United Kingdom
  • Puma Energy (UK) Limited, Westerleigh Terminal Oakley Green Farm Lane, Westerleigh BS37 8QE Bristol United Kingdom
  • RAFFINERIA DI GELA S.P.A, Contrada Piana del Signore CP35 93012 Gela (CL) Sicily Italy
  • Steptoe & Johnson LLP, Av Louise, 489 1050 Brussels Belgium

Substance names and other identifiers

[A complex combination of hydrocarbons produced by distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5 It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 220°C (194°F to 428°F).]
A complex combination of hydrocarbons produced by distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5. It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 220°C (194°F to 428°F).
C&L Inventory
Low boiling point modified naphtha
A complex combination of hydrocarbons produced by distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5. It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 220°C (194°F to 428°F).
C&L Inventory, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures
Naphtha (petroleum), full-range alkylate
EC Inventory, C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures
Naphtha (petroleum), full-range alkylate; Low boiling point modified naphtha [ complex combination of hydrocarbons produced by distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5 It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90 °C to 220 °C (194°F to 428°F).]
A complex combination of hydrocarbons produced by distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5. It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 220°C (194°F to 428°F).
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Naphtha (petroleum), full-range alkylate; Low boiling point modified naphtha
A complex combination of hydrocarbons produced by distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5. It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 220°C (194°F to 428°F).
Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
Naphtha, petroleum, full-range alkylate
A complex combination of hydrocarbons produced by distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5. It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 220°C (194°F to 428°F).
Other
(Keerulise koostisega süsivesinike segu, mis tekib isobutaani ja monoolefiinsete süsivesinike, tavaliselt C3 kuni C5, reaktsiooniproduktide destillatsioonil. Koosneb peamiselt hargnenud ahelaga küllastunud süsivesinikest, mille süsiniku aatomite arv on valdavalt vahemikus C7 kuni C12, ning on keemistemperatuuriga umbes 90°C kuni 220 °C.) (et)
C&L Inventory
(Složeni sastav ugljikovodika proizveden destilacijom proizvoda reakcije izobutana s monoolefinskim ugljikovodicima koji obično imaju broj ugljikovih atoma u području od C3 do C5. Sastoji se od pretežito razgrananih zasićenih ugljikovodika koji imaju broj ugljikovih atoma pretežito u području od C7 do C12 i vriju u području približno od 90 ºC do 220 ºC.) (hr)
C&L Inventory
[(Složitá směs uhlovodíků získaná destilací reakčních produktů isobutanu a monoolefinických uhlovodíků, obvykle s počtem uhlíkových atomů v rozmezí C3 až C5 . Je složena převážně z nasycených uhlovodíků s rozvětveným řetězcem s počtem uhlíkových atomů převážně v rozmezí C7 až C12 a s rozmezím teploty varu přibližně 90 °C až 220 °C.] (cs)
C&L Inventory
[Kompleks blanding av hydrokarboner fremstilt ved destillasjon av produktene fra reaksjonen mellom isobutan og monoolefinhydrokarboner, vanligvis C3 til C5. Består for det meste av forgrenede, mettede hydrokarboner, hovedsakelig C7 til C12, med omtrentlig kokepunktsintervall fra 90 °C til 220 °C (194 °F til 428 °F).] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov pridobljena z destilacijo reakcijskih produktov izobutana in monoolefinskih ogljikovodikov, običajno s številom ogljikovih atomov v območju med C3 in C5. Sestoji pretežno iz razvejanih nasičenih ogljikovodikov s številom ogljikovih atomov pretežno v območju med C7 in C12 ter z vreliščem v območju približno med 90 °C in 220 °C.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen, hergestellt durch Destillation der Reaktionsprodukte von Isobutan mit Monoolefinen mit Kohlenstoffzahlen gewöhnlich im Bereich von C3 bis C5; besteht vorwiegend aus verzweigten gesättigten Kohlenwasserstoffen mit Kohlenstoffzahlen überwiegend im Bereich von C7 bis C12 mit einem Siedebereich von etwa 90 °C bis 220 °C] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná destiláciou produktov reakcie izobutánu s monoalkénmi s počtom atómov uhlíka prevažne v rozmedzí od C3 do C5. Pozostáva predovšetkým z nasýtených uhľovodíkov s rozvetveným reťazcom a s počtom atómov uhlíka prevažne v rozmedzí od C7 do C12. Má teplotu varu v rozmedzí približne od 90 °C do 220 °C.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi produsă prin distilarea produşilor de reacţie a izobutanului cu hidrocarburi mono-olefine având, de obicei, numărul de atomi de carbon cuprins între C3 şi C5. Constă predominant în hidrocarburi ramificate saturate cu număr de atomi de carbon cuprins între C7 şi C12 şi cu punct de fierbere cuprins între aproximativ 90°C şi 220°C (194°F şi 428°F).] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts, destilējot izobutāna un monoolefīnu rindas ogļūdeņražu (parasti ar oglekļa atomu skaitu no C3 līdz C5) reakcijas produktus. Sastāv pārsvarā no sazarotās ķēdes piesātinātajiem ogļūdeņražiem, galvenokārt ar oglekļa atomu skaitu no C7 līdz C12, aptuvenā viršanas temperatūra no 90°C līdz 220°C (194°F līdz 428°F).] (lv)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas distiliuojant izobutano ir monoalkenų, kurių anglies atomu skaičius paprastai yra nuo C3 iki C5, reakcijos produktus. Jį sudaro daugiausia šakotos grandinės sotieji angliavandeniliai, turintys anglies atomų skaičių daugiausia nuo C7 iki C12, ir kurių virimo temperatūra maždaug nuo 90 °C iki 220 °C (nuo 194 °F iki 428 °F).] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet izobután főleg C3-C5 szénatomszámú monoolefinekkel lejátszódó reakciójának termékeiből desztillálással nyernek. Főleg elágazó láncú telített szénhidrogénekből áll, melyek szénatomszáma főleg a C7-C12 tartományban, forráspontja kb. a 90°C-tól 220°C-ig (194°F-től 428°F-ig) terjedő tartományban van.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που παράγεται με απόσταξη των προϊόντων αντίδρασης ισοβουτανίου με μονοολεφινικούς υδρογονάνθρακες με αριθμό ατόμων άνθρακα που κυμαίνεται συνήθως από C3 έως C5. Συνίσταται κυρίως από κορεσμένους υδρογονάνθρακες διακλαδισμένης αλυσίδας, με αριθμό ατόμων άνθρακα κυρίως μεταξύ C7 και C12 που αποστάζουν μεταξύ 90 °C και 200 °C περίπου.] (el)
C&L Inventory
[Комплексна комбинация от въглевдодороди, получена при дестилация на реакционните продукти от изобутан с моноолефинови въглеводороди, обикновено с брой на въглеродните атоми от C3 до C5 включително. Състои се основно от наситени въглеводороди с разклонена верига с брой на въглеродните атоми преобладаващо в интервала от C7 до C12 включително и дс температура на кипене приблизително в интервала от 90°C до 220°C (194°F до 428°F).] (bg)
C&L Inventory
Alacsony forráspontú módosított benzin (hu)
C&L Inventory
Benzin (nyersolaj), teljes alkilátum (hu)
C&L Inventory
Benzyna (ropa naftowa), szeroki alkilat (pl)
C&L Inventory
Benzínová frakce (ropná), široká alkylátová frakce (cs)
C&L Inventory
combinación compleja de hidrocarburos producida por destilación de productos de reacción de isobutano con hidrocarburos monoolefínicos con un número de carbonos normalmente dentro del intervalo de C3 a C5; compuesta principalmente de hidrocarburos saturados de cadena ramificada con un número de carbonos en su mayor parte dentro del intervalo de C7 a C12 y con un intervalo de ebullición aproximado de 90 °C a 220 °C (es)
C&L Inventory
Combinaison complexe d'hydrocarbures produite par distillation des produits de réaction de l'isobutane avec des hydrocarbures monooléfiniques généralement en C3 à C5. Se compose d'hydrocarbures saturés, en majorité à chaîne ramifiée, dont le nombre de carbones se situe principalement dans la gamme C7-C12 et dont le point d'ébullition est compris approximativement entre 90°C et 220°C. (fr)
C&L Inventory
Combinazione complessa di idrocarburi ottenuta per distillazione dei prodotti di reazione di isobutano con idrocarburi monoolefinici, a numero di atomi di carbonio normalmente nell'intervallo C3-5. È costituita in prevalenza da idrocarburi saturi a catena ramificata con numero di atomi di carbonio prevalentemente nell'intervallo C7-12 e punto di ebollizione nell'intervallo 90 °C - 220 °C ca. (da 194°F a 428°F). (it)
C&L Inventory
Combinação complexa de hidrocarbonetos obtida por destilação dos produtos da reacção de isobutano com hidrocarbonetos monoolefínicos com número de átomos de carbono geralmente na gama C3 a C5. É constituída predominantemente por hidrocarbonetos saturados de cadeia ramificada com número de átomos de carbono predominantemente na gama C7 a C12 e destilação no intervalo aproximado de 90 °C a 220 °C. (pt)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen door destillatie van de reactieproducten van isobutaan met enkelvoudig onverzadigde koolwaterstoffen, overwegend C3 tot en met C5. Bestaat voornamelijk uit verzadigde koolwaterstoffen met vertakte keten, overwegend C7 tot en met C12, met een kooktraject van ongeveer 90°C tot 220°C. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider fremstillet ved destillation af produkterne fra reaktionen mellem isobutan og monoolefiniske carbonhydrider, sædvanligvis C3 til og med C5. Den består af overvejende forgrenede, mættede carbonhydrider, overvejende C7 til og med C12, med kogeinterval omtrent fra 90 °C til 220 °C (194 ºF til 428 ºF). (da)
C&L Inventory
Fracţia nafta (petrol), întreaga gamă de compuşi alchil (mt)
C&L Inventory
Fracţia nafta modificată cu punct de fierbere la temperaturi scăzute (mt)
C&L Inventory
Gemodificeerde nafta met laag kookpunt (nl)
C&L Inventory
Komplex blandning av kolväten erhållen genom destillation av produkterna från reaktionen mellan isobutan och monoolefinkolväten, främst C3 till C5. Består främst av grenade, mättade kolväten, i synnerhet C7 till C12, med ungefärligt kokpunktsintervall från 90 °C till 220 °C. (sv)
C&L Inventory
Lavtkogende modificeret nafta (da)
C&L Inventory
lavtkokende modifisert nafta (no)
C&L Inventory
Ligroīns (nafta), smagais alkilāts (lv)
C&L Inventory
Lågkokande modifierad nafta (sv)
C&L Inventory
Madala keemispunktiga modifitseeritud raskbensiin (et)
C&L Inventory
Matalalla kiehuva modifioitu teollisuusbensiini (fi)
C&L Inventory
modificirana nafta z nizko temperaturo vrelišča (sl)
C&L Inventory
Modifikovaná nízkovroucí benzínová frakce (cs)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu tislaamalla isobutaanin reaktiotuotteita mono-olefiinisten hiilivetyjen kanssa, joiden hiililuvut yleensä ovat C3:sta C5:een. Koostuu pääasiassa haarautunutketjuisista tyydyttyneistä hiilivedyistä, joiden hiililuvut ovat pääasiassa välillä C7:stä C12:een ja jotka kiehuvat likimäärin välillä 90°C:sta 220°C:een (194°F:sta 428°F:iin). (fi)
C&L Inventory
Nafta (aardolie), totaalfractie, gealkyleerd (nl)
C&L Inventory
Nafta (petroleum), brett kokpunktsintervall, alkylat- (sv)
C&L Inventory
nafta (petroleum), full-range alkylat (no)
C&L Inventory
nafta (petrolio), frazioni di alchilazione ad ampio intervallo di ebollizione (it)
C&L Inventory
nafta (petróleo) alquilato de la serie completa (es)
C&L Inventory
Nafta (petróleo), de largo intervalo de destilação, de alquilação (pt)
C&L Inventory
nafta (zemeljsko olje), alkilat iz celotnega območja (sl)
C&L Inventory
Nafta modificada de baixo ponto de ebulição (pt)
C&L Inventory
nafta modificada de bajo punto de ebullición (es)
C&L Inventory
nafta modificata con basso punto di ebollizione (it)
C&L Inventory
naphta modifié à point d'ébullition bas (fr)
C&L Inventory
Naphta à large coupe (pétrole), alkylation;naphta modifié à bas point d'ébullition;[Combinaison complexe d'hydrocarbures produite par distillation des produits de réaction de l'isobutane avec des hydrocarbures monooléfiniques comportant généralement entre 3 et 5 atomes de carbones (C3-C5). Se compose principalement d'hydrocarbures saturés à chaîne ramifiée comportant majoritairement entre 7 et 12 atomes de carbone (C7-C12) et dont l'intervalle d'ébullition est compris approximativement entre 90 oC et 220 oC (entre 194 et 428 oF).] (fr)
C&L Inventory
Naphtha (Erdöl), schweres Alkylatbenzin (de)
C&L Inventory
naphtha (råolie), full-range alkylat (da)
C&L Inventory
Naphtha, niedrigsiedend, modifiziert (de)
C&L Inventory
Nisko-vrijući modificirani benzin (hr)
C&L Inventory
Niskowrząca modyfikowana frakcja benzynowa (pl)
C&L Inventory
O combinaţie complexă de hidrocarburi produsă prin distilarea produşilor de reacţie a izobutanului cu hidrocarburi mono-olefine având, de obicei, numărul de atomi de carbon cuprins între C3 şi C5. Constă predominant în hidrocarburi ramificate saturate cu număr de atomi de carbon cuprins între C7 şi C12 şi cu punct de fierbere cuprins între aproximativ 90°C şi 220°C (194°F şi 428°F). (mt)
C&L Inventory
Pirminis benzinas (nafta), visų frakcijų alkilatas (lt)
C&L Inventory
Raskbensiin (nafta), kogu alkülaatfraktsioon (et)
C&L Inventory
Teollisuusbensiini (maaöljy), laajan tislausalueen alkylaatti (fi)
C&L Inventory
Teški benzin (nafta), alkilat punog područja vrenja (hr)
C&L Inventory
upravený benzín s nízkou teplotou varu (sk)
C&L Inventory
Zemā temperatūrā virstošs modificēts ligroīns (lv)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana podczas destylacji produktów reakcji izobutanu z węglowodorami monoolefinowymi o liczbie atomów węgla zwykle w zakresie od C3 do C5. Składa się przede wszystkim z nasyconych węglowodorów o rozgałęzionym łańcuchu węglowym o liczbie atomów węgla w zakresie od C7 do C12, wrzących w zakresie temp. od ok. 90°C do 220°C. (pl)
C&L Inventory
ťažký benzín (ropný), alkylátový, s celým rozsahom teplôt varu (sk)
C&L Inventory
Žematemperatūris modifikuotas pirminis benzinas (lt)
C&L Inventory
νάφθαΝάφθα (πετρελαίου), προϊόν αλκυλίωσης, πλήρους σύστασης (el)
C&L Inventory
Τροποποιημένη νάφθα χαμηλού σημείου ζέσεως (el)
C&L Inventory
Модифициран нискооктанов бензин с ниска температура на кипене (bg)
C&L Inventory
Нискооктанов бензин (нефт) , широка фракция алкилати (bg)
C&L Inventory
Alkylates
Registration dossier
ALCOILADO LEVE
Registration dossier
ALCOILADO LEVE ALCOILADO PESADO
Registration dossier
ALCOILADO PESADO
Registration dossier
Alkilat
Registration dossier
Special Gasoline
Registration dossier
64741-64-6
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
649-274-00-9
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Other (100%) [1]
C Substance type
Petroleum product (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
-60 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 2 studies submitted
  • 1 study processed
R Boiling point
-20 - 260 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 1 study submitted
  • 1 study processed
R Relative density
0.62 - 0.88 @ 15 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
240 kPa @ 37.8 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 1 study submitted
  • 1 study processed
R Flash point
-40 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 4 studies submitted
  • 2 studies processed
R Autoflammability / self-ignition
280 - 470 °C @ 101.3 - 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Extremely flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 1 study processed
R kinematic viscosity (in mm²/s)
1 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning Insufficient hazard data available (further information necessary) (1)

Short–term toxicity to fish

Study results
  • 16 studies submitted
  • 2 studies processed
P/RResults
LL50 (4 days) 8.2 - 10 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 14
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EL50 (21 days) 10 mg/L [1]
NOELR (21 days) 2.6 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 12 studies submitted
  • 1 study processed
P/RResults
EL50 (48 h) 4.5 mg/L [1]
NOELR (48 h) 500 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 11
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
NOELR (21 days) 2.6 - 16 mg/L [2]
EL50 (21 days) 10 - 40 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 16 studies submitted
  • 1 study processed
P/RResults
EL50 (4 days) 3.7 mg/L [1]
EL50 (72 h) 3.1 mg/L [1]
NOELR (72 h) 500 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 15
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (40 h) 15.41 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.9 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 286.4 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 837.5 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1 066.67 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 410 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 152 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 178.57 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 640 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 43 studies submitted
  • 1 study processed
P/RResults
LD50 5 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 2 40
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 39 studies submitted
  • 1 study processed
M/CInterpretations of results
Not classified [1]

inhalation
Studies with data
Key study 1
Supporting study 38
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 44 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study 43
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5 610 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 95 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 3 90
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 45 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 43
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 43 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 41
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 22 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study 1
Supporting study 21
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 50 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study 1
Supporting study 49
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 402 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 18
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 13
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 2 8
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route:
No adverse effect observed NOAEC 9 869 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Inhalation route:
No adverse effect observed NOAEC 20 000 mg/m³ (chronic, rat)
Effect on developmental toxicity
Dermal route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 23 900 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant