Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Nitric acid
  • IUPAC name: nitric acid
  • Other names
EC / List no.:
231-714-2
CAS no.:
7697-37-2
Index number:
007-004-00-1
Molecular formula:
HNO3
SMILES:
ON(=O)=O
InChI:
InChI=1S/HNO3/c2-1(3)4/h(H,2,3,4)
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
31
Of which contain:
1 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP07) approved by the European Union, this substance causes severe skin burns and eye damage and may intensify fire (oxidiser).

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic if inhaled and may be corrosive to metals.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye damage.

Breakdown of all 2455 C&L notifications submitted to ECHA

Skin Corr. 1A H314 Harmonised Classification
Ox. Liq. 2 H272 Harmonised Classification
Met. Corr. 1 H290
Acute Tox. 3 H331
Eye Dam. 1 H318
Ox. Liq. 3 H272
Acute Tox. 1 H330
Repr. 1B H360
Flam. Liq. 2 H225
Eye Irrit. 2 H319
STOT RE 2 H373
Skin Irrit. 2 H315
STOT SE 3 H336
Skin Corr. 1B H314
Acute Tox. 2 H330
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • R

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 82 active registrations under REACH, 2 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 10 000 000 - 100 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: washing & cleaning products, fertilisers, polishes and waxes and air care products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates). Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as reactive substance.

This substance can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material).

This substance is used in the following products: fertilisers, washing & cleaning products, metal surface treatment products, pH regulators and water treatment products, non-metal-surface treatment products and laboratory chemicals.

This substance is used in the following areas: agriculture, forestry and fishing, scientific research and development, building & construction work and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment. This substance is used for the manufacture of: food products, electrical, electronic and optical equipment and fabricated metal products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, treatment of articles by dipping and pouring, mixing in open batch processes, non-industrial spraying, roller or brushing applications, hand mixing with intimate contact only with personal protective equipment available, laboratory work and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as reactive substance.

This substance is used in the following products: washing & cleaning products, pH regulators and water treatment products, metal surface treatment products, non-metal-surface treatment products and fertilisers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers, laboratory work, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, as processing aid, in processing aids at industrial sites, manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following products: pH regulators and water treatment products, washing & cleaning products, non-metal-surface treatment products, metal surface treatment products, water treatment chemicals, semiconductors and laboratory chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals, electrical, electronic and optical equipment, food products, plastic products, metals and fabricated metal products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, treatment of articles by dipping and pouring, laboratory work and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: as processing aid, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, of substances in closed systems with minimal release and manufacturing of the substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, laboratory work, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and in processing aids at industrial sites.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep only in original packaging; do not breathe the dust, fume, gas, mist, vapours or spray; keep away from clothing or other combustible materials; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; take any precaution to avoid mixing with combustibles or other incompatible materials specified by manufacture/supplier; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Wash contaminated clothing before reuse. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Immediately call a poison center or doctor/physician. Absorb spillage to prevent material damage. If swallowed: rinse mouth. Do not induce vomiting. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Storage statements

Store this substance in a corrosive resistant container with a resistant inner liner (or in other specified container type); in a closed container.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • AB Achema, Jonalaukio km. Ruklos sen. LT55550 Jonavos r. Lithuania
  • Acros Organics bvba, Janssen Pharmaceuticalaan 3a B-2440 Geel Belgium
  • ADP FERTILIZANTES, S.A., Estrada Nacional nº 10 - Apt 88 Salgados da Póvoa 2616-907 ALVERCA PORTUGAL Portugal
  • Agropolychim JSC, Industrial zone 9160 Devnya Varna Bulgaria
  • ANWIL SA, Torunska 222 87-805 Wloclawek kuj-pom Poland
  • AREVA NC, Bat 71 26701 Pierrelatte France
  • AS DBT, Narva mnt 7D 10117 Tallinn Estonia
  • Avantor Performance Materials Poland S.A., Sowińskiego 11 44-100 Gliwice Poland
  • Avocet Infinite plc, 25 Palace Street TD15 1HN Berwick-upon-Tweed Northumberland United Kingdom
  • BASF Antwerpen N.V., Haven 725, Scheldelaan 600 2040 Antwerpen 4 Antwerpen Belgium
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BONDALTI CHEMICALS, S.A., Quinta da Industria Beduido 3860-680 Estarreja Portugal
  • Borealis Agrolinz Melamine GmbH, St. Peter-Str. 25 4021 Linz Austria
  • Borealis Chimie, 20 ter, rue de BEZONS 92400 COURBEVOIE France
  • BOREALIS-PRODUITS ET ENGRAIS CHIMIQUES DU RHIN, CD 52 68490 Ottmarsheim France
  • BorsodChem, Bolyai ter 1 3700 Kazincbarcika Hungary
  • BorsodChem MCHZ, Chemická 2039/1 709 00 Ostrava Czech Republic
  • CF Fertilisers UK Ltd, Ince CH2 4LB Chester Cheshire United Kingdom
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • COMPO Expert GmbH, Krögerweg 10 48155 Münster NRW Germany
  • Coty Services and Logistics GmbH, Berliner Allee 65 64295 Darmstadt Germany
  • Covestro Deutschland AG, Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany
  • DEKRA Assurance Services GmbH OR07, Handwerkstr. 15 70565 Stuttgart Germany
  • DOW OLEFINVERBUND GMBH, Strasse B 13 D-06258 Schkopau Germany
  • DUSLO, Administrativna budova ev.č 1236 927 03 Šaľa Slovakia
  • ELC Group s.r.o., Karolinska 650/1 186 00 Prague 8 Czech Republic
  • EuroChem Antwerpen NV, Haven 725, Scheldelaan 600 2040 Antwerp Belgium
  • Explosia a.s., Semtín 107 530 02 Pardubice Czech Republic
  • Fertiberia, S.A., Paseo de la Castellana 259 D -Planta 48 28046 Madrid Spain
  • Fibrant B.V., Mauritslaan 49 6129 EL Urmond Netherlands
  • Fisher Scientific UK Ltd, Bishop Meadow Rd LE11 5RG Loughborough Leicestershire United Kingdom
  • FUJIFILM Electronic Materials (Europe) N.V., Keetberglaan 1A Haven 1061 2070 Zwijndrecht Antwerp Belgium
  • Grupa Azoty S.A., ul. Kwiatkowskiego 8 33-101 Tarnow Poland
  • Grupa Azoty Zakłady Azotowe Kędzierzyn Spółka Akcyjna, skr. poczt. 163 ul. Mostowa 30A 47-220 Kędzierzyn-Kożle Poland
  • Grupa Azoty Zakłady Azotowe „Puławy” S.A., al. Tysiąclecia Państwa Polskiego 13 24-110 Puławy Poland
  • Honeywell Specialty Chemicals Seelze GmbH, Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany
  • INEOS Manufacturing Deutschland GmbH, Alte Strasse 201 50769 Koeln Germany
  • Kayaku Safety Systems Europe a. s., Bobrky 2271 755 01 Vsetin Czech Republic
  • KFT Chemieservice GmbH, Im Leuschnerpark 3 64347 Griesheim Germany
  • KTR Europe GmbH, Mergenthalerallee 77 65760 Eschborn Germany
  • Lifosa-2, Juodkiskio 50 LT-57502 Kedainiai Lithuania
  • Lifosa-4, Juodkiskio 50 LT-57502 Kedainiai Lithuania
  • Lonza Cologne GmbH, Nattermannallee 1 50829 Cologne Germany
  • Lovochemie, a.s., Terezinska 57 410 02 Lovosice Czech Republic
  • MAXAM TAN SAS, Chemin des Soldats s/n 62670 Mazingarbe France
  • Merck KGaA, Frankfurter Strasse 64293 Darmstadt Germany
  • Nalco Limited, P.O. Box 11, Winnington Avenue, CW8 4DX Northwich, Cheshire United Kingdom
  • NEOCHIM PLC, East Industrial Zone, Himkombinatska Str. 6403 Dimitrovgrad Haskovo Bulgaria
  • NEW KARVALI FERTILISERS s.a., 139str Xenofontos, Kallithea Attiki GR176 74 Athens Attiki Greece
  • NitricoMax, Carretera Valencia s/n 43110 La Canonja Tarragona Spain
  • Nitrogénművek Zrt., Hősök tere 14 8105 Pétfürdő Veszprém Hungary
  • NobelNC Europe Ltd OR1, Elliott House Kilwinning Road KA12 8TG IRVINE AYRSHIRE United Kingdom
  • NobelNC Europe Ltd OR3, Elliott House Kilwinning Road KA12 8TG IRVINE AYRSHIRE United Kingdom
  • OCI Nitrogen B.V., Mijnweg 1 6167AC Geleen Netherlands
  • OXAQUIM S.A., C/Gregal, 3. Urbanizacion "Parc Llevant" 43764 El Catllar Tarragones Spain
  • Petrokemija d.d. Kutina, Aleja Vukovar 4 HR-44320 Kutina Croatia
  • Radici Chimica Deutschland GmbH, Dr. Bergius Strasse 6 D 06729 Elsteraue OT Troeglitz Germany
  • Radici Chimica S.p.A., via Fauser 50 28100 Novara Italy
  • REACh ChemConsult GmbH, Strehlener Straße 14 01069 Dresden Germany
  • RHODIA OPERATIONS, 40 rue de la Haie Coq 93306 AUBERVILLIERS France
  • S.C. Chemgas Holding Corporation S.R.L., Sos. Calarasi km 4, Pavilion Administrativ 920120 Slobozia Ialomita Romania
  • S.C. NITROPOROS S.R.L., Soseaua Combinatului Nr. 14 505200 FAGARAS BRASOV Romania
  • S.C.GA- PRO- CO CHEMICALS S.A., UZINEI NR.2 617410 SAVINESTI Romania
  • Sasol Germany GmbH - OR, Anckelmannsplatz 1 D-20537 Hamburg Germany
  • SC AZOMURES SA, Gheorghe Doja 540237 TARGU MURES MURES Romania
  • sc donauchem srl, portului nr.1 145200 Turnu Magurele Teleorman Romania
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SIGMA-ALDRICH CHIMIE SARL, 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France
  • Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom
  • SKW Stickstoffwerke Piesteritz GmbH, Möllensdorfer Straße 13 06886 Lutherstadt Wittenberg Germany
  • Synthesia, a.s., Semtín103 53002 Pardubice Czech Republic
  • Umicore NV/SA, Rue du Marais 31 1000 Brussels Belgium
  • VWR International BVBA, Haasrode Researchpark 2020 3001 Leuven Belgium
  • Yara AB, BOX 4505 S-20320 Malmo Sweden
  • Yara France, IMMEUBLE OPUS 12 77 ESPLANADE DU GENERAL DE GAULLE CS 90047 92914 PARIS LA DEFENSE CEDEX France
  • Yara GmbH & Co. KG, Hanninghof 35 D-48249 Dülmen Germany
  • Yara Italia SpA, Via Begnigno Crespi, 57 20159 Milano Italy
  • Yara Norge AS, Drammensveien 131 N-0277 Oslo Norway
  • Yara Sluiskil B.V., Industrieweg 10 4541HJ Sluiskil Netherlands
  • Yara Suomi Oy, Bertel Jumgin aukio 9 FI-02600 Espoo Finland
  • Yara Tertre S.A./N.V, Rue de la Carbo,10 B-7333 Tertre Belgium
  • Arcerion GmbH, Gabrielenstr. 15 80636 München Germany
  • BNH-OIL Polska Sp. z o.o., ul.Tadeusza Rejtana 17, lok 14 02-516 Warszawa Poland

Other names

  • -
  • Hydrogen nitrate
  • hydrogen trioxonitrate(1−)
  • NITRIC ACID
  • Nitric Acid (67%) [for General Organic Chemistry]
  • Nitric acid (Salpetersäure)
  • nitric acid ... %
  • nitric acid ...%
  • nitric acid 50-70 %
  • nitric acid 6 %
  • Nitric acid 60%
  • Nitric acid, 50%
  • Nitric acid, CAS N" 7697-37-2, Radici Chimica S.p.A.
  • Nitric acid, CAS N° 7697-37-2, Radici Chimica Deutschland GmbH
  • nitric acid...%
  • Nitric aicd
  • nitric-acid-
  • not available
  • Salpetersäure
  • Salpeterzuur
  • TET nitric acid
  • tric acid ... %
  • Nitric acid
  • nitric acid ... %
  • Acid, Nitric
  • acido nitrico
  • Acidum nitricum
  • Aqua Fortis
  • aquafortis
  • Azotic Acid
  • Concentrated nitric acid
  • Fumic Acid
  • HNO3 12% (BASF ART No. 57419788)
  • HNO3 60% (BASF ART No. 50041245)
  • HNO3 68% (BASF ART No. 50041510)
  • Hydrogen nitrate
  • kwas azotowy
  • kyselina dusičná technická
  • Nitric Ac.EG 100%
  • Nitric acid
  • Nitric acid (8CI, 9CI)
  • Nitric acid (HONO2)
  • Nitric acid in solution
  • Nitric acid t.p. 87%
  • Nitric Acid technical grade 21%
  • Nitric acid, anhydrous
  • Nitric acid, fuming
  • Nitric acid, high grade
  • Nitric acid, technical ...%
  • Nitryl hydroxide
  • ODDA zuur (BASF ART No. 55505242)
  • Ontsluitingszuur (BASF ART No. 55505401)
  • Red fuming nitric acid
  • SalpeterS 60, SalpeterS 65, SalpeterS 68, SalpeterS k, SalpeterS pu
  • Salpetersaeure
  • salpetersaure
  • Saltpetre acid
  • Spirit of nitre
  • Technical nitric acid

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 3 studies submitted
  • 3 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [3]
C Odour
Other (100%) [3]
C Substance type
Inorganic (100%) [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 4 studies submitted
  • 4 studies processed
R Melting / freezing point
-42 - -41.59 °C [4]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-41.15 °C

Boiling point

Study results
  • 5 studies submitted
  • 4 studies processed
R Boiling point
83 - 87 °C @ 100 - 101.325 kPa [4]

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 4
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
82.85 °C

Density

Study results
  • 5 studies submitted
  • 2 studies processed
R Density
1.513 g/cm³ @ 20 °C [1]
R Relative density
1.513 @ 20 °C [1]

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.513

Vapour pressure

Study results
  • 5 studies submitted
  • 4 studies processed
R Vapour pressure
65.328 - 50 000 Pa @ 20 - 100 °C [15]

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 1 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
62 hPa @ 19.85 °C

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Water solubility

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
500 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Yes (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 3 studies submitted
  • 3 studies processed
C Dissociating properties
Yes (100%) [3]
R Dissociation constant
-1.38 - 0 [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 5 studies submitted
  • 5 studies processed
R dynamic viscosity (in mPa s)
0.617 - 2.27 [8]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 5
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No hazard identified (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 8 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 12 g/L [1]

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence 2 1
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
Local Effects
Long-term: Other toxicological threshold
Acute /short term: Other toxicological threshold
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Hazard unknown (no further information necessary)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
EYE Exposure
High hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
Local Effects
Long-term: Other toxicological threshold
Acute /short term: Other toxicological threshold
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Hazard unknown (no further information necessary)
EYE Exposure
High hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
Low bioaccumulation potential
Absorption values
Oral: 50 %
Dermal: 50 %
Inhalation: 50 %

Acute toxicity

Study results
oral
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
oral
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
inhalation
  • 7 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 2.65 mg/L air (rat) [1]
M/CInterpretations of results
Other [1]

inhalation
Studies with data
Key study 1
Supporting study 2
Weight of evidence 1
Other 3
Data waiving
no waivers
dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
other routes
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route:
Adverse effect observed LC50 2 650 mg/m³

Irritation / corrosion

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: eye
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No study available
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 1 study submitted
  • 1 study processed
P/RResults
NOAEL (rat): 1 500 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 10 studies submitted
  • 1 study processed
P/RResults
NOAEC (rat): 2.15 ppm [1]

Study data: inhalation
Studies with data
Key study
Supporting study 1
Weight of evidence 7 2
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route - systemic effects:
No adverse effect observed NOAEC 4.11 mg/m³ (subchronic, rat)
Inhalation route - local effects:
No adverse effect observed NOAEC 4.11 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study
Supporting study
Weight of evidence 1 11
Other
Data waiving
no waivers
Study data: in vivo
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence 5
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 1 500 mg/kg bw/day (subacute, rat)
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 1 500 mg/kg bw/day (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant