Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Ammonia, anhydrous
  • IUPAC name: ammonia
  • Other names
EC / List no.:
231-635-3
CAS no.:
7664-41-7
Index number:
007-001-00-5
Molecular formula:
H3N
SMILES:
N
InChI:
InChI=1S/H3N/h1H3
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
71
Of which contain:
1 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance causes severe skin burns and eye damage, is toxic if inhaled, is very toxic to aquatic life and is a flammable gas.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic to aquatic life with long lasting effects.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye damage.

Breakdown of all 2344 C&L notifications submitted to ECHA

Aquatic Acute 1 H400 Harmonised Classification
Flam. Gas 2 H221 Harmonised Classification
Acute Tox. 3 H331 Harmonised Classification
Skin Corr. 1B H314 Harmonised Classification
Aquatic Chronic 2 H411
Eye Dam. 1 H318
Aquatic Chronic 1 H410
Press. Gas (Liq.) H280
STOT SE 3 H336
Press. Gas (Comp.) H280
STOT SE 3 H335
Acute Tox. 4 H302
Skin Corr. 1A H314
Acute Tox. 2 H330
Acute Tox. 3 H301
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 194 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 10 000 000 - 100 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: cosmetics and personal care products, heat transfer fluids, washing & cleaning products and coating products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: industrial spraying, mixing in open batch processes, transfer of chemicals at dedicated facilities, transfer of substance into small containers, roller or brushing applications, non-industrial spraying and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).

This substance is used in the following products: pH regulators and water treatment products, laboratory chemicals, extraction agents, fertilisers, coating products, metal surface treatment products, non-metal-surface treatment products, textile treatment products and dyes, photo-chemicals, heat transfer fluids, water treatment chemicals and pharmaceuticals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: agriculture, forestry and fishing and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment. This substance is used for the manufacture of: chemicals, pulp, paper and paper products, textile, leather or fur, food products and wood and wood products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, hand mixing with intimate contact only with personal protective equipment available, batch processing in synthesis or formulation with opportunity for exposure, roller or brushing applications and non-industrial spraying.

Other release to the environment of this substance is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: fertilisers, laboratory chemicals, coating products, adhesives and sealants, inks and toners, pH regulators and water treatment products, pharmaceuticals, photo-chemicals, water treatment chemicals, heat transfer fluids, paper chemicals and dyes, textile treatment products and dyes, washing & cleaning products, cosmetics and personal care products and extraction agents. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers, laboratory work, closed batch processing in synthesis or formulation, mixing in open batch processes and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: adhesives and sealants, washing & cleaning products, coating products, cosmetics and personal care products, textile treatment products and dyes, pH regulators and water treatment products, non-metal-surface treatment products, water treatment chemicals, paper chemicals and dyes, metal surface treatment products, heat transfer fluids, pharmaceuticals, extraction agents and photo-chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment. This substance is used for the manufacture of: chemicals, textile, leather or fur, pulp, paper and paper products, plastic products and fabricated metal products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, hand mixing with intimate contact only with personal protective equipment available and industrial spraying.

Release to the environment of this substance can occur from industrial use: as processing aid, in processing aids at industrial sites, in the production of articles, of substances in closed systems with minimal release and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: In case of leaking gas fire do not extinguish unless leak can be stopped safely. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • AB Achema, Jonalaukio km. Ruklos sen. LT55550 Jonavos r. Lithuania
  • ADP FERTILIZANTES, S.A., Estrada Nacional nº 10 - Apt 88 Salgados da Póvoa 2616-907 ALVERCA PORTUGAL Portugal
  • Afton Chemical S.P.R.L. (Woluwe), Alma Court Lenneke Marelaan, 8 B-1932 St-Stevens-Woluwe Belgium
  • Agropolychim JSC, Industrial zone 9160 Devnya Varna Bulgaria
  • AllessaProduktion GmbH, Alt-Fechenheim 34 60386 Frankfurt am Main Germany
  • Amcor Flexibles Winterbourne, Winterbourne Road Stoke Gifford BS34 6PT Bristol South Gloucestershire United Kingdom
  • Ameropa Düngemittel GmbH, Ferdinandstraße 55-57 20095 Hamburg Germany
  • Amurco SRL Bacau, Chimiei nr.1 600289 Bacau Romania
  • ANWIL SA, Torunska 222 87-805 Wloclawek kuj-pom Poland
  • ARKEMA S.R.L. Socio Unico, Via Pregnana 63 20017 Rho Milano Italy
  • AS DBT, Narva mnt 7D 10117 Tallinn Estonia
  • Ashland Services BV (0311), Noordweg 9 3336 LH Zwijndrecht Netherlands
  • Avantor Performance Materials Poland S.A., Sowińskiego 11 44-100 Gliwice Poland
  • AVESTRA CHEMICAL SERVICES OY, ORs, Uotilantie 35 01860 Perttula Finland
  • B-Lands Consulting (811260-6), World Trade Center 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • BASF Antwerpen N.V., Haven 725, Scheldelaan 600 2040 Antwerpen 4 Antwerpen Belgium
  • BASF Lampertheim GmbH, Chemiestrasse 22 68619 Lampertheim Germany
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Bayer AG, Kaiser-Wilhelm-Allee 51373 Leverkusen Germany
  • BENS consulting d.o.o. (OR HIP Azotara), Bakovniška 7 1240 Kamnik Slovenia
  • Biofert Ltd, Constantinou Paparigopoulu P.O. Box 58363 3733 Limassol Cyprus
  • BNH-OIL Polska Sp. z o.o., ul.Tadeusza Rejtana 17, lok 14 02-516 Warszawa Poland
  • Borealis Agrolinz Melamine GmbH, St. Peter-Str. 25 4021 Linz Austria
  • Borealis Chimie, 20 ter, rue de BEZONS 92400 COURBEVOIE France
  • Borealis L.A.T GmbH, St. Peter-Str. 25 4021 Linz Austria
  • BOREALIS-PRODUITS ET ENGRAIS CHIMIQUES DU RHIN, CD 52 68490 Ottmarsheim France
  • Borghi S.p.A., Via Leopardi, 39 22070 Grandate (CO) Italy
  • BorsodChem, Bolyai ter 1 3700 Kazincbarcika Hungary
  • BP Chemicals Ltd, Chertsey Rd TW16 7BP Sunbury on Thames Middlesex United Kingdom
  • British Steel ltd, Admin Centre Brigg Road DN16 1BP Scunthorpe North Lincolnshire United Kingdom
  • C.S.B. GmbH, Düsseldorfer Straße 113 47809 Krefeld Germany
  • CEPSA Química, S.A., Torre CEPSA Paseo de Castellana 259A 28046 Madrid Spain
  • CF Fertilisers UK Ltd, Ince CH2 4LB Chester Cheshire United Kingdom
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (ZIBO ZHENGDA POLYURETHANE CO., LTD), Room 002, Regus Harcourt Centre HW77 D02 Dublin Ireland
  • Chemical Standards SIA, Ritausma 31 LV-2127 Medemciems Olaine parish Latvia
  • Chemservice S.A. (4T8L), 5, an de Laengten 6776 Grevenmacher Luxembourg
  • Chemservice S.A. (H5P7), 5, an de Laengten 6776 Grevenmacher Luxembourg
  • CHT Austria GmbH, Aeueleweg 3 6812 Meiningen Austria
  • CHT Germany GmbH, Bismarckstr. 102 72072 Tuebingen Germany
  • CHT OR 13, Bismarckstr. 102 72072 Tuebingen Germany
  • CRAY VALLEY SA OR8, 2 Place Jean Millier 92400 Courbevoie France
  • DIAMO, s.p., Máchova 201 47127 Stráž pod Ralskem Czech Republic
  • DniproAZOT Trade, Stochovska 50/821 16100 Praha Czech Republic
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-10, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-7, Postbus 48 NL-4530 AA Terneuzen Netherlands
  • Dow Benelux B.V. OR-51, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW CHEMICAL COMPANY LTD, Diamond House, Lotus Park Kingsbury Crescent Middx UB7 0DQ Staines Middx United Kingdom
  • Dow France SAS, 23 Avenue Jules Rimet 93200 La Plaine Saint Denis France
  • DSM Coating Resins B.V., Ceintuurbaan 5 8022 AW Zwolle Netherlands
  • DUSLO, Administrativna budova ev.č 1236 927 03 Šaľa Slovakia
  • DyStar Colours Distribution GmbH, Am Prime-Parc 12 65479 Raunheim Germany
  • Ercros SA, Avenida Diagonal 593-595 08014 Barcelona Spain
  • Ferti-Solutions B.V., Zandtangerweg 46 9584AL Mussel Netherlands
  • Fertiberia, S.A., Paseo de la Castellana 259 D -Planta 48 28046 Madrid Spain
  • Fujimi Europe GmbH, Schlossstrasse 5 D-74653 Ingelfingen Germany
  • Gazprom Marketing and Trading France22, 68 avenue des Champs-Elysées 75008 Paris France France
  • GE.MA.R srl, via Colle Marracone 03034 Casalvieri Italy
  • Grupa Azoty S.A., ul. Kwiatkowskiego 8 33-101 Tarnow Poland
  • Grupa Azoty Zaklady Chemiczne "POLICE" Spolka Akcyjna, Kuznicka 1 72-010 Police Poland
  • Grupa Azoty Zakłady Azotowe Kędzierzyn Spółka Akcyjna, skr. poczt. 163 ul. Mostowa 30A 47-220 Kędzierzyn-Kożle Poland
  • Grupa Azoty Zakłady Azotowe „Puławy” S.A., al. Tysiąclecia Państwa Polskiego 13 24-110 Puławy Poland
  • GUARDIAN INDUSTRIES NAVARRA, POL. INDUSTRIAL MONTES DE CIERZO S/N, A 68 Km 86 31500 TUDELA NAVARRA Spain
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Holborn Europa Raffinerie GmbH, Moorburger Strasse 18 21079 Hamburg Germany
  • Huntsman (Europe) BVBA - OR1, Everslaan 45 B-3078 Everberg Belgium
  • HUNTSMAN HOLLAND BV, Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands
  • Huntsman Textile Effects (Germany) GmbH, Rehlinger Str. 1 D-86462 Langweid a.Lech Germany
  • INEOS Manufacturing Deutschland GmbH, Alte Strasse 201 50769 Koeln Germany
  • INEOS Nitriles (UK) Ltd (M & I), PO Box 62 Seal Sands TS2 1TX Middlesbrough United Kingdom
  • Intertek Deutschland GmbH 14, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • INTERTEK FRANCE, Ecoparc 2 27400 HEUDEBOUVILLE France
  • Kao Chemicals Europe, S.L. (2), Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain
  • Kemira Oyj, Energiakatu 4 P.O.Box 330 FI-00101 HELSINKI Finland
  • KMG ITALIA S.r.l., VIA UMBRIA 4 20098 SAN GIULIANO MILANESE (MI) Italy
  • KMG ITALIA S.r.l. (OR), VIA UMBRIA 4 20098 SAN GIULIANO MILANESE Italy
  • Kraton Chemical AB OR1, Massvagen 15 P.O. Box 66 SE-820 22 Sandarne Sweden
  • Kuraray Europe GmbH (OR1), Philipp-Reis-Str. 4 65795 Hattersheim Germany
  • L'OREAL, 14 rue Royale 75008 Paris France
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • LANXESS N.V., Scheldelaan 420 Haven 507 2040 Antwerpen Belgium
  • Lifosa-2, Juodkiskio 50 LT-57502 Kedainiai Lithuania
  • Lifosa-4, Juodkiskio 50 LT-57502 Kedainiai Lithuania
  • Lifosa-8, Juodkiskio str. 50 LT-57502 Kedainiai Lithuania
  • Linde Aktiengesellschaft, Seitnerstrasse 70 D 82049 Pullach Germany
  • Lonza Cologne GmbH, Nattermannallee 1 50829 Cologne Germany
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Lubrizol Limited, The Knowle, Nether Lane Hazelwwod DE56 4AN Derby Derbyshire United Kingdom
  • Lučební závody Draslovka a.s. Kolín, Havlíčkova 605 280 02 Kolín IV Czech Republic
  • Merck Performance Materials GmbH, Rheingaustrasse 190-196 65203 Wiesbaden Germany
  • Michelman International Belgium SPRL OR, Zoning Industriel B-6790 Aubange Belgium
  • Mitsui and Co. Deutschland G.M.B.H. Head Office (Düsseldorf), Herzogstrasse 15 D-40217 Düsseldorf Germany
  • Monument Chemical, Haven 1972 Ketenislaan 3 9130 Kallo Belgium
  • Monument Chemical_ORKY, Haven 1972 Ketenislaan 3 9130 Kallo Belgium
  • Muntajat B.V, 19th Floor, Tower E, WTC The Hague Prinses Margrietplantsoen 78-A 2595 The Hague Netherlands
  • Nalco Europe B.V., Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands
  • Nalco Limited, P.O. Box 11, Winnington Avenue, CW8 4DX Northwich, Cheshire United Kingdom
  • NEOCHIM PLC, East Industrial Zone, Himkombinatska Str. 6403 Dimitrovgrad Haskovo Bulgaria
  • NEW KARVALI FERTILISERS s.a., 139str Xenofontos, Kallithea Attiki GR176 74 Athens Attiki Greece
  • Nippon Gases Belgium nv, Metropoolstraat 17 2900 Schoten Antwerpen Belgium
  • Nitrofert AS, Estonia, Jarvekula tee 1 30197 Kohtla-Jarve Estonia
  • Nitrogénművek Zrt., Hősök tere 14 8105 Pétfürdő Veszprém Hungary
  • Nouryon Functional Chemicals AB, Stenunge Allé 3 - SE-444 85 Stenungsund - Sweden
  • Nouryon Functional Chemicals B.V., Velperweg 76 6824 BM Arnhem Netherlands
  • Nouryon Surface Chemistry AB, Stenunge Allé 3 - S-44485 Stenungsund - Sweden
  • NUTRIEN EUROPE S.A., Avenue Louise 326 (bte36) B - 1050 BRUXELLES Belgium
  • OCI Fertilizers Trade & Supply B.V., Mijnweg 1 6167 AC Geleen Netherlands
  • OCI Nitrogen B.V., Mijnweg 1 6167AC Geleen Netherlands
  • OQEMA GmbH, Aachener Str. 258 41061 Moenchengladbach Germany
  • OSTCHEM Germany GmbH, Erdmannstr. 10 22765 Hamburg Germany
  • OSTCHEM Germany GmbH Sev, Erdmannstr. 10 22765 Hamburg Germany
  • OSTCHEM Germany GmbH_Ch, Erdmannstr. 10 22765 Hamburg Germany
  • OSTCHEM Germany GmbH_M, Erdmannstr. 10 22765 Hamburg Germany
  • Petrochemical Commercial Company (UK) Ltd, 24, GROSVENOR GARDENS SW1W 0DH LONDON EUROPE United Kingdom
  • Petrokemija d.d. Kutina, Aleja Vukovar 4 HR-44320 Kutina Croatia
  • PHOSINT LIMITED, 21 Vasili Michailidi 3026 Limassol Cyprus
  • Plougarlis Petros & co. corporated, 5th Km Giannitsa - Thessaloniki 58100 Giannitsa, Thessaloniki Greece
  • polihimiki - Lamprinos I & SIA OE, DA 10, Industrial Area 57022 Thessaloniki Sindos Greece
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR3, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • Procter & Gamble Manufacturing Belgium N.V., Temselaan 100 1853 Strombeek-Bever Belgium
  • Procter & Gamble Manufacturing GmbH, Sulzbacher Strasse 40 65824 Schwalbach am Taunus Germany
  • Procter & Gamble Product Supply (U.K.) Limited, The Heights, Brooklands KT13 OXP Weybridge, Surrey United Kingdom
  • PRODUCTOS CAPILARES L'OREAL S.A., Calle Josefa Valcarcel num. 48 28027 MADRID Spain
  • PROTELOR, 6 rue Barbès B. P. 177 92305 LEVALLOIS-PERRET France
  • Purolite Ltd., Llantrisant Business Park CF72 8LF Llantrisant Wales United Kingdom
  • Quality Chemicals S.L., C/ Fornal, 35, Pol. Ind. Can Comelles-Sud 08292 Esparreguera Barcelona Spain
  • Ramboll Environment & Health GmbH, Werinherstraße 79 Gebäude 32a 81541 München Germany
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brussels Belgium
  • Reach Only Representative (Ireland) Ltd (abqico), VPR House Main St F12 FC64 Swinford Co. Mayo Ireland
  • REACHLaw ltd, Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • RHODIA OPERATIONS, 40 rue de la Haie Coq 93306 AUBERVILLIERS France
  • Rudolf GmbH, Altvaterstr. 58 - 64 82538 Geretsried Germany
  • Ruhr Oel GmbH, Pawiker Strasse 30 45896 Gelsenkirchen Germany
  • S.C. Chemgas Holding Corporation S.R.L., Sos. Calarasi km 4, Pavilion Administrativ 920120 Slobozia Ialomita Romania
  • S.C. NITROPOROS S.R.L., Soseaua Combinatului Nr. 14 505200 FAGARAS BRASOV Romania
  • S.C.GA- PRO- CO CHEMICALS S.A., UZINEI NR.2 617410 SAVINESTI Romania
  • SA DABEER, C/ Pasaje Arrahona 18 2º 08210 Barbera del Vallés Spain
  • SABIC Petrochemicals B.V., Europaboulevard 1 6135 LD Sittard Netherlands
  • Saltigo GmbH, HSEQ-RA Kaiser-Wilhelm-Allee 40 D-51373 Leverkusen Germany
  • sanofi chimie, 82 avenue Raspail 94250 Gentilly France
  • SC AZOMURES SA, Gheorghe Doja 540237 TARGU MURES MURES Romania
  • sc donauchem srl, portului nr.1 145200 Turnu Magurele Teleorman Romania
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • Setagro Ltd, General Gurko 18, et.2 8000 Bourgas Bulgaria
  • SI Group UK (UKAA) Ltd, Tenax Road M17 1WT Manchester United Kingdom
  • Siegfried PharmaChemikalien Minden GmbH, Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SKW Stickstoffwerke Piesteritz GmbH, Möllensdorfer Straße 13 06886 Lutherstadt Wittenberg Germany
  • SLOVNAFT, a.s., Vlcie hrdlo 1 824 12 Bratislava Slovakia
  • SNF S.A.S., ZAC de Milieux 42163 Andrézieux France
  • Sokolovská uhelná, právní nástupce, a. s., Staré náměstí 69 CZ35601 Sokolov Czech Republic
  • Specialty Electronic Materials Netherlands B.V., Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • STEPAN EUROPE SA, Chemin JONGKIND 38340 VOREPPE France
  • Synthomer (UK) Limited, Central Road Templefields CM20 2BH Harlow Essex United Kingdom
  • Tazzetti S.p.A., Corso Europa 600/a 10088 Volpiano Torino Italy
  • TC NV OR1, Bergstraat 32 BE-3945 HAM Belgium
  • The Monckton Coke and Chemical Company Limited, PO Box 25 Royston S714BE Barnsley South Yorkshire United Kingdom
  • TSGE_2019-006, Lavesstraße 4 31137 Hildesheim Germany
  • UBE Corporation Europe, S.A.U., Poligono Industrial El Serrallo, s/n 12100 Castellón Spain
  • UMCO GmbH, Georg-Wilhelm-Straße 187 21107 Hamburg Germany
  • Unipetrol RPA, Litvinov - Zaluzi 1 43670 Litvinov Czech Republic
  • Uralchem Assist, Johannssenstrasse 10 30159 Hannover Germany
  • Versum Materials Netherlands B.V., Kanaalweg 15 PO Box 3193 3502 GD Utrecht Netherlands
  • Yara AB, BOX 4505 S-20320 Malmo Sweden
  • Yara Brünsbuttel GmbH, Holstendamm 2 D-25572 Büttel Schleswig-Holstein Germany
  • Yara France, IMMEUBLE OPUS 12 77 ESPLANADE DU GENERAL DE GAULLE CS 90047 92914 PARIS LA DEFENSE CEDEX France
  • Yara GmbH & Co. KG, Hanninghof 35 D-48249 Dülmen Germany
  • Yara International ASA OR1, Drammensveien 131 N-0277 Oslo Norway
  • Yara International ASA OR2, Drammensveien 131 N-0277 Oslo Norway
  • Yara International ASA OR3, Drammensveien 131 N-0277 Oslo Norway
  • Yara International ASA OR5, Drammensveien 131 N-0277 Oslo Norway
  • Yara International ASA OR6, Drammensveien 131 N-0277 Oslo Norway
  • Yara Italia SpA, Via Begnigno Crespi, 57 20159 Milano Italy
  • Yara Norge AS, Drammensveien 131 N-0277 Oslo Norway
  • Yara Sluiskil B.V., Industrieweg 10 4541HJ Sluiskil Netherlands
  • Yara Suomi Oy, Bertel Jumgin aukio 9 FI-02600 Espoo Finland
  • Yara Tertre S.A./N.V, Rue de la Carbo,10 B-7333 Tertre Belgium
  • Yara UK Ltd, Harvest House Europarc DN37 9TZ Grimsby N.E.LincolnshireUK United Kingdom
  • Yordas GmbH, Äußere Nürnberger Str. 62, 91301 Forchheim Germany
  • Yordas Limited, Lancaster Environment Centre Lancaster University LA1 4YQ Lancaster United Kingdom
  • Arcerion GmbH, Gabrielenstr. 15 80636 München Germany
  • Asia Union Electronic Chemical Corporation, Mörchingerstr. 117 14169 Berlin Germany
  • Evonik Antwerpen NV, Tijsmanstunnel West 2040 Antwerpen 4 Flanders Belgium
  • Henkel Nederland B.V., Brugwal 11 3432 NZ Nieuwegein Netherlands
  • IVICT Europe GmbH, Kennedydamm 19 40476 Düsseldorf Germany
  • OSTCHEM Germany GmbH, Erdmannstr. 10 22765 Hamburg Germany
  • Trammo SARL, 23 Rue Balzac 75008 Paris France

Other names

  • -
  • 007-001-00-5
  • AMMONIA
  • Ammonia Anhydrous
  • Ammonia, Anhydrous
  • AMMONIA-GAS for Gaseous formula only
  • ammoniac
  • Ammoniak
  • Ammoniakwasser (<10% Ammoniak)
  • ammonium
  • Ammonium anhydrous
  • Amonyak
  • Anhydrous Ammonia
  • Azan
  • Azane
  • FRE Ammonia, anhydrous
  • nitrogen trihydride
  • Ammonia, anhydrous
  • Ammonia
  • Ammonia (8CI, 9CI)
  • AMMONIA 20% SOLUTION
  • Ammonia anhydrous
  • ammonia anhydrous liquefied
  • Ammonia Gas
  • Ammonia Hydrogen Nitrite
  • Ammonia liquefied
  • Ammonia liquefied technical pure
  • ammonia solution
  • Ammonia Solution 25%
  • Ammonia, anhydrous
  • Ammonia, aqueous solution
  • Ammonia-14N
  • AMMONIA-GAS
  • Ammoniac
  • Ammoniaca anidra
  • Ammoniak
  • ammoniak (feuchte Ware)
  • ammoniak bezwodny
  • Ammoniak wasserfrei
  • Ammoniak, wasserfrei
  • Ammoniakwasser
  • Ammoniaque
  • ammonium
  • Ammonium amide
  • Ammonium amide (7CI)
  • Amoniak
  • Amoniak bezwodny
  • amoniak gazowy
  • amonijak bezvodni
  • Anhydrous Ammonia
  • Anhydrous liquid ammonia
  • Azane
  • hydrogen nitride
  • Kapalný čpavek
  • Liquefied anhydrous ammonia
  • Liquid ammonia for technical use
  • liquid ammonia technical
  • PiaNOx - A
  • Salmiakgeist
  • SOLUCIÓN AMONIACAL
  • Technical liquid ammonia
  • Čpavek
  • Čpavková voda
  • амоняк, безводен
  • ammonia

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Gaseous (100%) [1]
C Odour
Ammonia-like (100%) [1]
C Substance type
Inorganic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Gaseous (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 1 study processed
R Melting / freezing point
-77.7 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-77.15 °C

Boiling point

Study results
  • 4 studies submitted
  • 2 studies processed
R Boiling point
-33.33 - -33 °C [2]

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
-33.15 °C

Density

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 5 studies submitted
  • 2 studies processed
R Vapour pressure
614.9 - 1 003 kPa @ 10 - 25 °C [5]

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence 2
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
0.23 @ 20 °C

Water solubility

Study results
  • 5 studies submitted
  • 3 studies processed
R Water solubility (mass/vol.)
444 - 895 g/L @ 0 - 28 °C [5]

Type of Study provided
Studies with data
Key study
Supporting study 1 1
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
482 g/L @ 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 1 study submitted
  • 1 study processed
R Autoflammability / self-ignition
651 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
650.85 °C

Flammability

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Study results
  • 1 study submitted
  • 1 study processed
R Oxidation reduction potential
-3 090 mV [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidation reduction potential at 20 °C
3 090 mV

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 3 studies submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
9.25 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 3 studies submitted
  • 1 study processed
R Other:
0.255 - 0.475 [4]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
0.507 - 1.621 Pa m³/mol @ 5 - 25 °C [4]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 1.1 µg/L (1)
Intermittent releases (freshwater) 6.8 µg/L (1)
Marine water 1.1 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) -
Sediment (freshwater) -
Sediment (marine water) -
Hazard for Air
Air -
Hazard for Terrestrial Organism
Soil -
Hazard for Predators
Secondary poisoning -

Short–term toxicity to fish

Study results
  • 8 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 750 - 109 000 µg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 5
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
68 µg/L

Long–term toxicity to fish

Study results
  • 4 studies submitted
  • 4 studies processed
P/RResults
NOEC (61 days) 1.2 mg/L [1]
NOEC (31 days) 48 µg/L [1]
LOEC (73 days) 22 µg/L [1]
LOEC (33 days) 50 µg/L [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3 1
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 5 studies submitted
  • 1 study processed
P/RResults
LC50 (48 h) 101 mg/L [1]
EC0 (48 h) 39.7 mg/L [1]
LOEC (48 h) 74 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
110 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (4 days) 790 µg/L [1]
LOEC (4 days) 1.3 mg/L [1]
LC50 (4 days) 4.07 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
790 µg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (18 days) 2.7 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
2.7 g/L

Toxicity to aquatic plants other than algae

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 47.6 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 47.6 mg/m³ repeated dose toxicity
Local Effects
Long-term: (DNEL) 14 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 36 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 6.8 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 6.8 mg/kg bw/day repeated dose toxicity
Local Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 23.8 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 23.8 mg/m³ repeated dose toxicity
Local Effects
Long-term: (DNEL) 2.8 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 7.2 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 68 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 68 mg/kg bw/day repeated dose toxicity
Local Effects
Long-term: - -
Acute /short term: - -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 6.8 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 6.8 mg/kg bw/day repeated dose toxicity
EYE Exposure
-

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Absorption values
Dermal: 10 %

Acute toxicity

Study results
oral
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 350 mg/kg bw (rat) [1]
M/CInterpretations of results
Toxic [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
inhalation
  • 3 studies submitted
  • 1 study processed
P/RResults
LC50 (60 min) 9.85 - 13.77 mg/L air (rat) [3]
LC50 (40 min) 14.17 mg/L air (rat) [1]
LC50 (20 min) 19.96 mg/L air (rat) [1]
LC50 (10 min) 28.13 mg/L air (rat) [1]
M/CInterpretations of results
Harmful [1]

inhalation
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
other routes
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Study data: respiratory
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 3 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 250 - 1 500 mg/kg bw/day [2]
LOAEL (rat): 750 - 1 500 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
Study data: inhalation
  • 5 studies submitted
  • 3 studies processed
P/RResults
LOAEL (rat): 105 - 175 mg/m³ air [2]
LOEL (guinea pig): 119 mg/m³ air [1]
NOAEC (rat): 35 mg/m³ air [1]

Study data: inhalation
Studies with data
Key study
Supporting study 1
Weight of evidence 4
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: in vivo
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
Study data: developmental
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study 2 2
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant