Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Lithium 12-hydroxystearate
  • IUPAC name: lithium(1+) 12-hydroxyoctadecanoate
  • Other names
EC / List no.:
231-536-5
CAS no.:
7620-77-1
Index number:
Molecular formula:
C18H35LiO3
SMILES:
[Li+].CCCCCCC(O)CCCCCCCCCCC([O-])=O
InChI:
InChI=1/C18H36O3.Li/c1-2-3-4-11-14-17(19)15-12-9-7-5-6-8-10-13-16-18(20)21;/h17,19H,2-16H2,1H3,(H,20,21);/q;+1/p-1
Type of substance:
Mono constituent substance
Origin:
Other
Registered compositions:
17
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.
According to the majority of notifications provided by companies to ECHA in CLP notifications no hazards have been classified.

Breakdown of all 1535 C&L notifications submitted to ECHA

Not Classified
Eye Irrit. 2 H319
Skin Irrit. 2 H315
STOT SE 3 H335
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 83 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 10 000+ tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: lubricants and greases.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid, outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal), industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting) and of articles where the substances are not intended to be released and where the conditions of use do not promote release. Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).

This substance can be found in complex articles, with no release intended: Vehicles (e.g. personal vehicles, delivery vans, boats, trains, metro or planes)), machinery, mechanical appliances and electrical/electronic products e.g. refrigerators, washing machines, vacuum cleaners, computers, telephones, drills, saws, smoke detectors, thermostats, radiators, large-scale stationary industrial tools), vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators. This substance can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), rubber (e.g. tyres, shoes, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).

This substance is used in the following products: lubricants and greases, metal working fluids and hydraulic fluids.

This substance is used for the manufacture of: machinery and vehicles and fabricated metal products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, roller or brushing applications, non-industrial spraying, treatment of articles by dipping and pouring, heat / pressure transfer fluids in closed systems and greasing at high energy conditions.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use as processing aid and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: lubricants and greases, polymers and metal working fluids.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, transfer of substance into small containers, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, laboratory work, closed processes with no likelihood of exposure and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: lubricants and greases and hydraulic fluids.

This substance is used for the manufacture of: machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, roller or brushing applications, industrial spraying, treatment of articles by dipping and pouring and greasing at high energy conditions.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ADEKA POLYMER ADDITIVES EUROPE SAS, 13 rue du 17 Novembre FR-68100 MULHOUSE France
  • AXEL CHRISTIERNSSON AB, Strandvägen 10 449 41 NOL Sweden
  • AXEL CHRISTIERNSSON BV, 1 Februariweg 13 4794 SM Heijningen Netherlands
  • AXEL France SAS, 30 Rue de Pied de Fond - Z.I. St Liguaire / CS 98821 79028 Niort France
  • Baerlocher GmbH, Freisinger Str. 1 85716 Unterschleissheim Germany
  • Belgian Shell N.V, S.A. Belgian Shell N.V. Cantersteen 47 Kantersteen Bruxelles 1000 Brussel Brussels Belgium
  • Belgian Shell S.A. (OR for CH), Kantersteen – Cantersteen 47 B-1000 Brussel - Bruxelles Belgium
  • Belgian Shell S.A. (OR for TR), Kantersteen – Cantersteen 47 B-1000 Brussel - Bruxelles Belgium
  • BP Europa SE, Überseeallee 1 20457 Hamburg Germany
  • BRUGAROLAS, S.A., Camino de la Riera, 36-44 Polígono Industrial Cova Solera 08191 RUBI Barcelona Spain
  • Cambridge Environmental Assessments, part of RSK ADAS Europe (Ireland) Ltd, Office Suite B, Bluebell Business Centre Old Naas Road D12XV7K Dublin Ireland
  • Carl Bechem GmbH, Weststraße 120 58089 Hagen Germany
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemie-Technik GmbH, Robert-Bosch-Str. 19 72189 Vöhringen Germany
  • Cogelsa, Comerç 08740 Sant Andreu de la Barca Barcelona Spain
  • CONDAT, avenue Frédéric Mistral 38670 Chasse sur Rhône France
  • CROMOGENIA UNITS S.A., Carrer 40 nº 14 POL. ZONA FRANCA 08040 BARCELONA Spain
  • DDP Specialty Products Germany GmbH , August-Wolff-Strasse 13 29699 Bomlitz Germany
  • Dow Silicones Belgium SPRL OR-2, PSRC - rue Jules Bordet Parc industriel C 7180 Seneffe Belgium
  • Dow Silicones Deutschland GmbH, PSRC - Rheingaustrasse 65201 Wiesbaden Germany
  • ELDON'S AEBE, 20 Souliou Street 143 43 N. Halkidona Athens Greece
  • ELVIGRO SA, Koritsas 17 143 43 N. Halkidon Attica Greece
  • Esso Raffinage S.A.S., Tour Manhattan, 5/6, Place de l'Iris 92400 Courbevoie France
  • ExxonMobil Petroleum & Chemical, BVBA, Polderdijkweg 2030 Antwerpen Belgium
  • FUCHS Lubricants Benelux NV, INDUSTRIEZONE HEIDEVELD 54 B-1654 Huizingen Vlaams-Brabant Belgium
  • Fuchs LUBRITECH GmbH, Werner-Heisenberg-Strasse 1 67661 Kaiserslautern Germany
  • FUCHS OIL CORPORATION (PL) Sp. z o.o., Ul. KUJAWSKA 102 44-101 GLIWICE Poland
  • FUCHS Schmierstoffe GmbH, Friesenheimer Str. 19 68169 Mannheim Germany
  • Gazprom Neft Lubricants Italia SpA, via bitritto km 7,800 70124 bari Italy
  • Global Lubricants Ltd, 7 sandwell business development centre oldbury road,smethwick b66 1nn west midlands United Kingdom
  • HH Compliance Ltd., Rubicon Building, CIT Campus Bishopstown none Cork Ireland
  • ILCO INDUSTRIALE S.r.l., Via fratelli Rosselli, 2 I-20090 Premenugo di Settala - MILAN Italy
  • IMPERATOR, 1 RUE DE BREUZE BP 59 59780 BAISIEUX France
  • INA MAZIVA Ltd. Member of INA Group, Radnicka cesta 175 10000 Zagreb Croatia
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • Ironsides Lubricants Ltd, Shield Street SK3 ODS Stockport Cheshire United Kingdom
  • Jet-Lube (Houston) (UK) Ltd, Reform Road SL6 8BY Maidenhead Berkshire United Kingdom
  • KAJO GmbH, Boschstr. 13 59609 Anröchte Nordrhein-Westfalen Germany
  • KRAFFT S.L., Ctra. Urnieta s/n 20140 Andoain Guipuzcoa Spain
  • LOTOS Oil S.A., Elblaska 135 80718 Gdansk Poland
  • Lubricant Consult GmbH, Gutenbergstraße 13 63477 Maintal Hessen Germany
  • Lubrizol Europe Coordination Center BVBA 30, Chaussee De Wavre 1945 Brussels Belgium
  • LUKOIL Neftohim Burgas AD (INTESMO), Western Industrial Zone 8104 Bourgas Bulgaria
  • MOL-LUB Lubricant Production Trade and Service Ltd., Fö ut 21. H-2931 Almasfüzitö Hungary
  • NAM&NAM Europe GmbH, Emil-Figge-Str. 80 44227 Dortmund Germany
  • NAM&NAM Europe GmbH, Emil-Figge-Str.80 44227 Dortmund Germany
  • NYCO-STPC, Zoning Industriel de Tournai Ouest 1 B-7503 Froyennes Belgium
  • OLIPES, c/aluminio, 2-3. Parque empresarial Borondo 28510 Campo Real Madrid Spain
  • ORLEN OIL Sp. z o.o., Opolska 114 31-323 Kraków Poland
  • P.P.H. "Fazi" Sp. z o. o., Komorowicka 9 43-500 Czechowice - Dziedzice Silesia Poland
  • PARAMO, a.s., Přerovská 560 53006 Pardubice Czech Republic
  • Peter Greven GmbH & Co. KG, Peter-Greven-Str. 20-30 53902 Bad Münstereifel Germany
  • PETRONAS LUBRICANTS ITALY S.P.A., Via Santena 1 10029 Villastellone Torino Italy
  • Petronas Lubricants Spain S.L.U., calle Isaac Peral n 1 08420 Canovelles Barcelona Spain
  • Petróleos de Portugal - Petrogal, S.A., Rua Tomás da Fonseca, Torres de Lisboa 1600-209 Lisboa Portugal
  • Proventus, Westland Square LS11 5SS Leeds United Kingdom
  • Przedsiębiorstwo Modex-Oil, ul. Sztumska 9 82-500 Kwidzyn Pomorskie Poland
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman 6, Box 5 B-1040 Brussels Belgium
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • Rhenus Lub GmbH & Co KG, Hamburgring 45 D-41179 Mönchengladbach Germany
  • ROCOL a division of ITW Ltd, Wakefield Road Swillington LS26 8BS Leeds West Yorkshire United Kingdom
  • ROWE Mineralölwerk GmbH, Langgewann 101 67547 Worms Germany
  • RS Clare & Co. Limited, Stanhope Street L8 5RQ Liverpool Merseyside United Kingdom
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19A Bus 6 MC-SQUARE Offices B-1831 Diegem Belgium
  • Setral, 13, rue Tannmuhle F-67310 Romanswiller France
  • Shell Deutschland Oil GmbH, Suhrenkamp 71-77, 22335 Hamburg Germany
  • Silesia Oil Sp. z o. o., Wapienna 2 43-174 Łaziska Górne Poland
  • SLIDER S.A., 294 Syngrou Andrea Avenue 17673 Kallithea Athens Greece
  • Specialty Electronic Materials Netherlands B.V. OR-1, Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • SPIREL, SPIREL S.A.S. ZA de Saint Firmin SPIREL S.A.S. ZA de Saint Firmin, Vineuil Saint Firmin 60500 Chantilly OISE France
  • TOTAL LUBRICANTS PLANT BEVERWIJK BV, NOORDERKADE, 30-32 1948 NR BEVERWIJK Netherlands
  • TOTAL ROMANIA SA, STEJARILOR STREET, 2 507055 CRISTIAN BRASOV Romania
  • TÜV SÜD Industrie Service GmbH, Westendstraße 199 80686 München Germany
  • TÜV SÜD Industrie Service GmbH, IS-USR-MUC Westendstraße 199 80686 Munich Germany
  • Verila Lubricants AD, 20, Zlaten Rog Str. 1407 Sofia Bulgaria Bulgaria
  • VERKOL S.A., BARRIO ZALAIN 42 31780 BERA NAVARRA Spain
  • VISCOL SpA a socio unico, Via Delle Piane N. 95 16019 Ronco Scrivia Genova Italy
  • Zeller+Gmelin GmbH & Co. KG, Schlossstraße 20 73054 Eislingen Germany
  • [Confidential], [Confidential]

Other names

  • -
  • Lithium 12-hydroxyoctadecanoate
  • Lithium 12-Hydroxystearate
  • Lithium 12-hydroxystearate EC 231-536-5
  • lithium(1+) 12-hydroxyoctadecanoate
  • lithium(1+) ion 12-hydroxyoctadecanoate
  • Octadecanoic acid, 12-hydroxy-, monolithium salt
  • Lithium 12-hydroxystearate
  • Smar ŁT4, ŁT4S, EP, EPX i inne o zawartości mydeł litowych “lithium 12hydroxystearate” od 3% do 9%

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 3 studies submitted
  • 3 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [3]
C Form
Not specified (67%), Powder (33%) [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Melting/freezing point

Study results
  • 10 studies submitted
  • 4 studies processed
R Melting / freezing point
167 - 231 °C @ 101.3 kPa [4]

Type of Study provided
Studies with data
Key study 4
Supporting study 4
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Density

Study results
  • 4 studies submitted
  • 3 studies processed
R Relative density
1.04 - 1.07 @ 20 - 22 °C [3]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 5
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Partition coefficient

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 5
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Water solubility

Study results
  • 8 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
46 µg/L @ 20 °C and pH 7.48 - 8.71 [1]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 5
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 3 studies submitted
  • 3 studies processed
R Surface tension
34 - 65.9 mN/m @ 1.01 - 1.07 g/L and 21 - 21.5 °C [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 3 studies submitted
  • 3 studies processed
C Interpretation of results
Non flammable (100%) [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
8.6 - 8.8 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 4 studies submitted
  • 2 studies processed
C Interpretation of results
Readily biodegradable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No exposure of soil expected (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 4 studies submitted
  • 3 studies processed
P/RResults
LL50 (4 days) 100 mg/L [3]
NOELR (4 days) 100 mg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 3 studies processed
P/RResults
EL50 (48 h) 100 mg/L [3]
NOELR (48 h) 100 mg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 3 studies submitted
  • 3 studies processed
P/RResults
EL50 (72 h) 100 - 160 mg/L [3]
NOELR (72 h) 100 - 160 mg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (28 days) 13 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: No DNEL required: short term exposure controlled by conditions for long-term
Local Effects
Long-term: (DNEL) 172 µg/cm² skin irritation/corrosion
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: No DNEL required: short term exposure controlled by conditions for long-term
Local Effects
Long-term: (DNEL) 86 µg/cm² skin irritation/corrosion
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 8 studies submitted
  • 5 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [3]
M/CInterpretations of results
Category 5 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 5
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
dermal
  • 3 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Practically nontoxic [1]

dermal
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed Discriminating dose 2 000 mg/kg bw
Dermal route:
No adverse effect observed Discriminating dose 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 6
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 4 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 13.9 - 695 mg/kg bw/day [4]

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study 1
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal
  • 6 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 111.25 - 1 089.75 mg/kg bw/day [2]

Study data: dermal
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Dermal route - systemic effects:
No adverse effect observed NOAEL 1 089.75 mg/kg bw/day (subacute, rat)
Dermal route - local effects:
Adverse effect observed NOAEL 860 µg/cm² (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Dermal route:
No adverse effect observed NOAEL 1 089.75 mg/kg bw/day (subacute, rat)
Effect on developmental toxicity
Dermal route:
No adverse effect observed NOAEL 1 089.75 mg/kg bw/day (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant