Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Zinc oxide
  • IUPAC name: oxozinc
  • Other names
EC / List no.:
215-222-5
CAS no.:
1314-13-2
Index number:
030-013-00-7
Molecular formula:
OZn
SMILES:
O=[Zn]
InChI:
InChI=1S/O.Zn
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
93
Of which contain:
14 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is very toxic to aquatic life and is very toxic to aquatic life with long lasting effects.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance may damage fertility or the unborn child, is harmful if swallowed, is harmful if inhaled and may cause damage to organs through prolonged or repeated exposure.

Breakdown of all 8200 C&L notifications submitted to ECHA

Aquatic Acute 1 H400 Harmonised Classification
Aquatic Chronic 1 H410 Harmonised Classification
Repr. 1A H360
Acute Tox. 4 H302
Acute Tox. 4 H332
STOT RE 2 H373
STOT SE 1 H370
Skin Irrit. 2 H315
Eye Irrit. 2 H319
STOT SE 3 H335
STOT RE 1 H372
Not Classified
Carc. 1A H350
Eye Dam. 1 H318
Acute Tox. 2 H300
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • R*

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 193 active registrations under REACH, 2 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Substance included in the Community Rolling Action Plan (CoRAP).
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:
Nanomaterials in the EU Market

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 000 - 1 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fillers, putties, plasters, modelling clay, coating products, metal surface treatment products, finger paints, polymers and washing & cleaning products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens).

Release to the environment of this substance can occur from industrial use: in the production of articles, formulation of mixtures and formulation in materials. Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators. This substance can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), metal (e.g. cutlery, pots, toys, jewellery), plastic (e.g. food packaging and storage, toys, mobile phones), wood (e.g. floors, furniture, toys) and fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).

This substance is used in the following products: polymers, coating products, fillers, putties, plasters, modelling clay, non-metal-surface treatment products, pH regulators and water treatment products, fertilisers and metal surface treatment products.

This substance is used in the following areas: formulation of mixtures and/or re-packaging, building & construction work, agriculture, forestry and fishing and health services. This substance is used for the manufacture of: plastic products, machinery and vehicles, mineral products (e.g. plasters, cement) and furniture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, treatment of articles by dipping and pouring, roller or brushing applications, non-industrial spraying, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, hand mixing with intimate contact only with personal protective equipment available and the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance is used in the following products: pH regulators and water treatment products, laboratory chemicals, fillers, putties, plasters, modelling clay, metal surface treatment products and polymers. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of substance into small containers, transfer of chemicals, closed batch processing in synthesis or formulation, mixing in open batch processes, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, closed, continuous processes with occasional controlled exposure, treatment of articles by dipping and pouring and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, in the production of articles, formulation in materials, manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

This substance is used in the following products: pH regulators and water treatment products, coating products, polymers, metal surface treatment products and fillers, putties, plasters, modelling clay. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals, mineral products (e.g. plasters, cement), electrical, electronic and optical equipment, pulp, paper and paper products and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, mixing in open batch processes, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, production of mixtures or articles by tabletting, compression, extrusion or pelletisation and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, as processing aid, in processing aids at industrial sites, formulation in materials and manufacturing of the substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, mixing in open batch processes, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), batch processing in synthesis or formulation with opportunity for exposure and handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders).

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), in the production of articles and formulation in materials.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If exposed or concerned: get medical advice/attention. Collect spillage.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Deutschland GmbH, Carl-Schurz-Strasse 1 41453 Neuss Germany
  • 3M France SAS, 1 Parvis de l'Innovation CS 20203 95006 Cergy-Pontoise Cedex France
  • 3M Italia s.r.l., Via Norberto Bobbio 21 20096 Pioltello (MI) Italy
  • A-ESSE S.P.A. FABBRICA OSSIDI DI ZINCO, via Conturli 16042 Carasco (GE) Italy
  • ADEKA POLYMER ADDITIVES EUROPE SAS, 13 rue du 17 Novembre FR-68100 MULHOUSE France
  • AFC, 38 rue de Vannes BP 70332 35600 REDON FRANCE France
  • ALBEMARLE CATALYSTS COMPANY B.V., Nieuwendammerkade 1-3 PO Box 37650 1030 BE Amsterdam Netherlands
  • ALBEMARLE EUROPE SPRL, Parc Scientifique (Einstein) Rue du Bosquet 9 1348 LOUVAIN-LA-NEUVE Belgium
  • Antaria Europe B.V., Hoogoorddreef 15 1101 BA Amsterdam Netherlands
  • Anthesis (Ireland) Limited, The Black Church St. Mary’s Place D07 P4AX Dublin Ireland
  • Arcadis Belgium NV, Koningsstraat 80 1000 Brussel Belgium
  • Asturiana de Zinc S.A., Zona Industrial Nº 1 33417 San Juan de Nieva (Castrillón) Asturias Spain
  • B-Lands Consulting (811245-9), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • Baerlocher GmbH, Freisinger Str. 1 85716 Unterschleissheim Germany
  • BASF Nederland B.V., Groningensingel 1 Postbus 1019 6801 MC Arnhem Netherlands
  • BASF Personal Care and Nutrition GmbH, Henkelstr. 67 40589 Düsseldorf Germany
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Befesa Zinc Óxido, S.A.U., Sangroniz Bidea 24 48150 Sondika Vizcaya Spain
  • Bootman Chemical Safety Ltd 023, Diss Business Centre IP21 4HD Diss United Kingdom
  • BrüggemannChemical, L. Brüggemann GmbH & Co. KG, Salzstrasse 131 74076 Heilbronn Baden-Württemberg Germany
  • C.S.B. GmbH, Düsseldorfer Straße 113 47809 Krefeld Germany
  • C.S.B. GmbH, Duesseldorfer Str.113 47809 Krefeld Germany
  • Cambridge Environmental Assessments part of RSK ADAS Europe (Ireland) Ltd, Office Suite B, BlueBell Business Centre Old Naas Road DB12XV7K Dublin Ireland
  • Carl Bechem GmbH, Weststraße 120 58089 Hagen Germany
  • CEA part of RSK ADAS Europe (Ireland) Ltd, Office Suite B, Blue Bell Business Centre Old Naas Road D12XV7K Dublin Ireland
  • cfm minerales, Camino de palos s/n. aptdo.345 12200 Onda Spain
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 HW77 Dublin Ireland
  • Chemical Worldwide Business S.A., Wspólna 6 62-400 Słupca Poland
  • Chemservice GmbH - (AF2Q), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice GmbH - (P9T1), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice GmbH - (PV0C), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemviron Carbon Ltd, Edgar House Lockett Road WN4 8DE Ashton-in-Makerfield Lancashire United Kingdom
  • Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1 65843 Sulzbach am Taunus Germany
  • Colorobbia España, S.A., CV-160 Km. 16,3 12192 Villafames Castellón Spain
  • colorobbia italia spa, via Pietramarina 53 via Pietamarina 123 50053 Sovigliana - Vinci Firenze Italy
  • CS Regulatory Ltd 1L-24, The Old Courthouse St Peters Churchyard DE1 1NN Derby United Kingdom
  • DE CRAENE NV, INDUSTRIEZONE 12 9770 KRUISHOUTEM Belgium
  • DENTSPLY DeTrey GmbH, DeTrey Strasse 1 78467 Konstanz Germany
  • Dipl.Ing. Herwig GmbH, Eppenhauser Str. 151 58093 Hagen Germany
  • Ege Italia s.r.l., verdi 88/b 23807 merate lecco Italy
  • ENDEKA Ceramics S.A., Ctra Cabanes Vall d'Alba km.4 12194 Vall d'Alba Castellón Spain
  • ENVIGO CRS SAU 053, Centro Industrial Santiga - Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • ESMALGLASS, S.A., Crta. CV-20 km. 2,3 12540 Villarreal Castellon Spain
  • Euro Support Manufacturing Czechia, s.r.o., Záluží 1 436 70 Litvínov Czech Republic
  • EverZinc Belgium, Boulevard Emile-de-Laveleye, 191 4020 Liège Belgium
  • EverZinc Nederland B.V., 2 Muggenweg 6245 AB Eijsden Zuid-Limburg Netherlands
  • EverZinc Norway AS, Hoffsg Postboks 1281 3251 Larvik Norway
  • ExxonMobil Petroleum & Chemical BVBA OR05, Polderdijkweg 2030 Antwerpen Belgium
  • ExxonMobil Petroleum & Chemical BVBA OR06, Polderdijkweg 2030 Antwerpen Belgium
  • ExxonMobil Petroleum & Chemical, BVBA, Polderdijkweg 2030 Antwerpen Belgium
  • Ferro France S.A.R.L., 43 rue Jeanne d'Arc 52115 Saint-Dizier Cedex France
  • Ferro Spain S.A., Carretera Valencia - Barcelona Km 61.5 12550 Almazora (Castellon) Spain
  • Firma Handlowa L-PAS Wojciech Wykland, Śląska 64c/15 80-389 Gdańsk Poland
  • Fritta, S.L.U, ctra. CV-20 km 8 12200 Onda Castellon Spain
  • GC Europe n.v., Interleuvenlaan 33 3001 Heverlee Belgium
  • GE.MA.R srl, via Colle Marracone 03034 Casalvieri Italy
  • GF Casting Solutions Leipzig GmbH, Georg-Fischer-Straße 2 04249 Leipzig Germany
  • Grillo Zinkoxid GmbH, Halberstaedterstrasse 15 38644 Goslar Germany
  • Grolman S.A.S., 14 rue Jacqueline Auriol Parc d’ activités des Murons 42160 ANDREZIEUX-BOUTHEON France
  • Grupa Azoty S.A., ul. Kwiatkowskiego 8 33-101 Tarnow Poland
  • H J Enthoven & Sons Ltd, Darley Dale DE4 2LE Matlock Derbyshire United Kingdom
  • H.C. Starck Tungsten GmbH, Landsberger Str. 98 80339 München Germany
  • Haldor Topsoe A/S, Nymøllevej 50 DK28000 Lyngby Denmark
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Honeywell Belgium NV OR-1000, Gaston Geenslaan 14 - 2nd Floor Arenberg Wetenschapspark B-3001 Heverlee Belgium
  • Incometal Nuova S.r.l., Via Viviani 8 20124 Milano Italia Italy
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • Isochem Kautschuk Gesellschaft mbH, Staatsrat-Schwamb-Str. 144 55278 Undenheim Rheinland-Pfalz Germany
  • Jemmtec Ltd T/A Magma Ceramics, Low Road Earlsheaton WF12 8BU Dewsbury W Yorks United Kingdom
  • Johnson Matthey Chemicals GmbH, Wardstrasse 17 D-46446 Emmerich am Rhein Germany
  • Johnson Matthey PLC, 5th Floor, 25 Farringdon Street EC4A 4AB London United Kingdom
  • Kobo Products SAS, 135 Rue Buissonnière Quartier Bouysset 31670 Labège France
  • KTR Europe GmbH, Mergenthalerallee 77 65760 Eschborn Germany
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • Lonza Cologne GmbH, Nattermannallee 1 50829 Cologne Germany
  • LORD Germany GMBH, Ottostrasse 28 41836 Hueckelhoven North Rhine - Westphalia Germany
  • LTS-REACH-OR_NANOPHASE, 15 Boulevard de Bury 16400 Angoulême France
  • Lubrizol France SAS, 25 Quai de France 76100 ROUEN France
  • Luxcontrol S.A. (OR18), 1, Avenue des Terres Rouges - 4004 Esch-sur-Alzette - Luxembourg
  • Luxcontrol S.A. (OR69), 1, Avenue des Terres Rouges 4331 Esch sur Alzette Luxembourg
  • Manufacture Française des Pneumatiques Michelin, Place des Carmes Déchaux 63040 Clermont-Ferrand Puy de Dôme France
  • Manufacture Française des Pneumatiques Michelin (OR CAN), Place des Carmes Déchaux 63040 Clermont Ferrand France
  • Manufacture Française des Pneumatiques Michelin (OR US), Place des Carmes Déchaux 63040 Clemront Ferrand France
  • MARANGONI SPA, VIA DEL GARDA 6 38068 ROVERETO (TN) Italy
  • MARIO PILATO BLAT, S.A., Paseo Alameda, 17 46010 Valencia Valencia Spain
  • Merck KGaA, Frankfurter Strasse 64293 Darmstadt Germany
  • MFPM Only Representative for Michelin Siam Co., Ltd., Place des Carmes Déchaux 63040 Clermont-Ferrand France
  • MFPM Only Representative for SOCIEDADE MICHELIN DE PARTICIPAÇÕES INDÚSTRIA E COMÉRCIO LTDA, Place des Carmes Déchaux 63040 Clermont-Ferrand France
  • MFPM Only Representative pour Michelin India Tamilnadu Tyres Private Limited, Place des Carmes Déchaux Site de Ladoux - Batiment G22 63040 Clermont-Ferrand France
  • Michelin España Portugal, S.A., Avenida de los Encuartes, 19 28760 Tres Cantos (Madrid) Spain
  • Michelin Polska S.A., ul. Leonharda 9 10-454 Olsztyn Poland
  • Michelin Reifenwerke AG & Co. Kommanditgesellschaft auf Aktien, Michelinstrasse 4 76185 Karlsruhe Germany
  • MINERALS 2000, S.A., Ctra. C.V. 160, Km. 16 12.192 Villafamés (Castellón) Spain
  • Miyoshi Europe SAS, 5 rue Paul Rieupeyroux 69800 Saint-Priest France
  • momaja s.r.o., Karolinska 650/1 186 00 Prague 8 Czech Republic
  • momaja s.r.o., Karolinská 650/1 186-00 Prague 8 Czech Republic
  • momaja s.r.o., Karolinská 650/1, 186 00 Prague 8 Czech Republic
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • Nickelhütte Aue GmbH, Rudolf-Breitscheid-Straße 65-75 D-08280 Aue Germany
  • Norkem BV, Het Voert 7 1613 KL Grootebroek Netherlands
  • Norkem Limited, Norkem House Bexton Lane WA16 9FB Knutsford Cheshire United Kingdom
  • Norzinco GmbH Harzer Zinkoxide, Landstrasse 93 38644 Goslar Germany
  • Performance Materials Ibérica, S.L.U., Av. Diagonal Num. 571 08029 Barcelona Spain
  • Peru Metals S.A., c/. Gregorio Gea 81 46920 Mislata Valencia Spain
  • PHARMEGIC HEALTHCARE LIMITED, Unit 23, Trinity Technology and Enterprise campus, Pearse Street D02WR66 Dublin 2 Ireland
  • PIRAIKI METAL RECYCLING S.A., 72nd Km National Road Athens-Lamia 32200 Thiva Greece
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • Przedsiębiorstwo Produkcyjno- Consultingowe ADOB Sp. z o.o. Sp. k., Kołodzieja 11 61-070 Poznań Poland Poland
  • QUIMIALMEL S.A., CL SAN ROQUE 15 12004 CASTELLON CASTELLON Spain
  • Quimidroga, S.A., Tuset, 26 08006 Barcelona Spain
  • REACh ChemConsult GmbH, Strehlener Str. 14 01069 Dresden Germany
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brussels Belgium
  • REACH GLOBAL SERVICES S.A., Rondpoint Schuman, 6 Box 5 B-1040 Brussels Belgium
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman 6 B-1040 Brussels Belgium
  • REACH INTEGRA, S.L., C/ Tomás Alba Edison, 2 41092 Sevilla Sevilla Spain
  • Reach Only Representative (Ireland) Ltd (znox), VPR House, Main Street F12 FC64 Swinford Co. Mayo Ireland
  • Reach Only Representative (Ireland) Ltd (zocm) , VPR House Main St F12 FC64 Swinford Co. Mayo Ireland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • REACHLaw Ltd. , Vänrikinkuja 3 JK 21, FI-02600 Espoo Finland Finland
  • REI Snc, via Majorana 8/B 35010 CADONEGHE (PD) Italy
  • RESACRIL, S.L., POL.IND.L'ALTERO. AVDA. DEL PALMAR, 8 46460 SILLA Spain
  • RS Bruce (Metals & Machinery) Ltd, March Street Darnall S9 5DQ Sheffield United Kingdom
  • SABIC Innovative Plastics BV, Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands
  • SABIC Petrochemicals B.V., Europaboulevard 1 6135 LD Sittard Netherlands
  • SC BERG METALLCHEM SRL, Calea SAGULUI Nr.143 300517 TIMISOARA TIMIS Romania
  • SC MER INVEST INDUSTRIES SRL, Sos. Nationala (DN 1) nr 12 105200 Baicoi Prahova Romania
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • Shell Catalyst & Technologies Leuna GmbH, Gebaude 8322 Am Haupttor D-06237 Leuna Leuna Germany
  • Shin-Etsu Silicones Europe BV, Bolderweg 32 1332 AV Almere Netherlands
  • Shin-Etsu Silicones Europe BV - Importer, Bolderweg 32 1332 AV Almere Netherlands
  • SILOX S.A., rue Wauters 144 4480 Engis Belgium
  • SILOX S.A. "OR HTCI", rue Wauters 144 4480 Engis Belgium
  • SILOX S.A. "OR TSIL", rue Wauters 144 4480 Engis Belgium
  • SlovZink, a.s., Továrenská 545 018 64 Košeca Slovakia
  • Società per Azioni Michelin Italiana, Corso Romania n. 546 10156 Torino Italy
  • Soleras Advanced Coatings BVBA, E3-Laan 75-79 9800 Deinze Belgium
  • Solvay Specialty Polymers Italy S.p.A., Viale Lombardia 20 20021 BOLLATE Italy
  • Stewardship Chemicals 17, Green Lowe Farm Shawclough Road, Waterfoot BB4 9SA Rossendale Lancashire United Kingdom
  • Sun Chemical B.V., Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands
  • Sustainability Support Services (Europe) AB, Markaskälsvägen 6 22647 Lund Sweden
  • TDK Electronics s. r. o., Feritova 1 787 15 Sumperk Czech Republic
  • The Acta Group EU BVBA (BE1), Place du Luxembourg 2 1050 Brussels Belgium
  • The Acta Group EU BVBA (BE30), Place du Luxembourg 2 1050 Brussels Denmark
  • TORRECID, S.A., Partida Torreta s/n 12110 ALCORA CASTELLON Spain
  • Toyota Tsusho Europe S.A., Belgicastraat 13 1930 Zaventem Belgium
  • TPC SA, Avenue du Colonel Prat 21850 Saint Apollinaire France
  • Traxys Europe SA, 19-21 Route Arlon same L-8009 Strassen Luxembourg Luxembourg
  • Traxys Metales y Quimicos SLU, Manuel Ferrero, 13 - Bajo 28036 Madrid Spain
  • Tyco Electronics EC Trutnov s.r.o., Komenského 821 Trutnov 54183 Trutnov Czech Republic Czech Republic
  • Tyco Electronics Raychem GmbH, Finsinger Feld 1 85521 Ottobrunn Bayern Germany
  • Tyco Electronics UK Limited, Faraday Road Dorcan SN3 5HH Swindon Wiltshire United Kingdom
  • TÜV SÜD Iberia S.A.U. (021), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • TÜV SÜD Iberia S.A.U. (041), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • TÜV SÜD Industrie Service GmbH, Westendstraße 199 80686 München Germany
  • UBE Corporation Europe, S.A.U., Poligono Industrial El Serrallo, s/n 12100 Castellón Spain
  • Umicore Thin Film Products AG, Alte Landstrasse 8 FL-9496 Balzers Liechtenstein
  • Unicat Catalyst Technologies, Dr van Peltlaan 13 1861KA Bergen Netherlands
  • UOP B.V.B.A., Noorderlaan 147 B-2030 Antwerp Belgium
  • Valspar b.v., Zuiveringweg 89 8243 PE Lelystad Netherlands
  • Venator Pigments UK Limited, Liverpool Road East ST7 3AA Kidsgrove Staffordshire United Kingdom
  • VIBIPLAST s.r.l., Via Modigliani 12-19 20022 Castano Primo (MI) Italy
  • WERCO METAL SRL, Str. Garii Nr. 10A RO-516100 Zlatna Alba County Romania
  • WIEHART GESMBH, Pernhofen 5 2064 Wulzeshofen Austria
  • WSP UK Ltd (OR1), The Victoria 150-182 The Quays M50 3SP Salford Greater Manchester United Kingdom
  • Yara UK Ltd, Harvest House Europarc DN37 9TZ Grimsby N.E.LincolnshireUK United Kingdom
  • YOKOHAMA INDUSTRIAL PRODUCTS ITALY S.R.L., Località Tamarete, SNC 66026 Ortona (CH) Italy
  • Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
  • Zincol ossidi Spa, via Adda 44/46 20040 Bellusco (Milano) Italy
  • Zinctimal Spain, S.L., Avda. Ferrocarril, 107 12560 Castellon Spain
  • ZM "Silesia" S.A. Ul. Konduktorska 8, 40-155 Katowice, Konduktorska 8 40-155 Katowice Poland
  • [Confidential], [Confidential]
  • Arcerion GmbH, Gabrielenstr. 15 80636 Muenchen Germany
  • Bisol Spa, Via degli Artigiani 40 31053 pieve di soligo treviso Italy
  • Charles River Laboratories Den Bosch B.V. OR42, Hambakenwetering 7 5231 DD 's-Hertogenbosch Netherlands
  • Henkel Electronic Materials (Belgium) N.V., Nijverheidsstraat 7 2260 Westerlo Belgium
  • Hydrometal, Rue du Parc Industriel 3 4480 Engis Belgium
  • momaja s.r.o., Karolinská 650/1 186-00 Prague 8 Czech Republic
  • Oxizinc - Agalsa S.L.U., Lloreda - Tremañes 33211 Gijón Asturias Spain
  • Ramboll Environment & Health GmbH, Werinherstraße 79 Gebäude 32a 81541 München Germany
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brussels Belgium
  • SAXONIA Technical Materials GmbH, Rodenbacher Chaussee 4 63457 Hanau Germany
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany

Other names

  • -
  • 030-013-00-7
  • 215-222-5 Zinc oxide - GH Chemicals
  • Cink-oxid
  • inc oxide
  • Oxid zinečnatý
  • Oxo zinc
  • Oxozinc
  • oxyde de zinc
  • Reaction mass of 1309-48-4 and 7631-86-9
  • Reaction mass of 1313-13-9 and 7758-99-8
  • Reaction mass of 13463-67-7 and 14807-96-6 and 21645-51-2 and 68037-59-2
  • UPV8
  • zin oxide
  • Zinc (II) oxide
  • ZINC OXIDE
  • Zinc oxide (CI 77947)
  • Zinc oxide (CI 77947) 
  • Zinc oxide (ZnO)
  • zinc oxide - poussières de fusion
  • zinc oxide / zinkoxid
  • Zinc Oxide Powder
  • Zinc oxide, ZnO
  • Zinc oxygen(2-)
  • Zinc(II) oxide
  • Zinc(II)oxide
  • Zinci oxidum
  • Zincoxide
  • Zinkoxid
  • Activox B
  • Afox
  • Albemarle SulfurSorb
  • e.g. Actisorb
  • e.g. G1
  • EGEZINC
  • EPM
  • EPM-E
  • Feedgrade
  • FINEX series, CANDY ZINC series, XY series, ZINCA-20, ZINC OXIDE NO.2, ZINC OXIDE SUPERFINE
  • K-AZO
  • Larvik Zinc oxide
  • Neige
  • OXIDO DE ZINC
  • OXIDO DE ZINC 80% MIN
  • OXIDO DE ZINC 85% MIN
  • OXIDO DE ZINC 90% MIN
  • OXIDO DE ZINC 91% MIN
  • OXIDO DE ZINC 92% MIN
  • OXIDO DE ZINC 93% MIN
  • OXIDO DE ZINC 94% MIN
  • OXIDO DE ZINC 95% MIN
  • OXIDO DE ZINC 96% MIN
  • OXIDO DE ZINC 97% MIN
  • OXIDO DE ZINC 98% MIN
  • OXIDO DE ZINC 99% MIN
  • OXIDO DE ZINC 99.5% MIN
  • OXIDO DE ZINC 99.8
  • OXIDO DE ZINC 99.8% MIN
  • OXIDO DE ZINC 99.9% MIN
  • OXIDO DE ZINC ACTIVO
  • OXIDO DE ZINC CALCINADO
  • OXIDO DE ZINC ESTANDARD
  • OXIDO DE ZINC FUSION
  • OXIDO DE ZINC GOMA
  • OXIDO DE ZINC GRANULADO
  • OXIDO DE ZINC WAELZ
  • oxizinc
  • Pharma
  • Red Seal
  • Technical Oxide
  • The substance is placed on the market both as a substance in pure formas a desulfurization catalyst (HTZ) and as a part of the chemical matrix of inorganic catalysts (i.e. regarded as a mixture according to Guidance for Identification and Naming of Substance under REACH and CLP, Feb 2014).
  • TO
  • Tradename for the substance when present as part of the catalyst, see section 3.4 for tradenames on mixtures containing the substance
  • TRANS ACTIVED ZINC OXIDE
  • TRANS PARENT ZINC OXIDE
  • USP ZnO
  • White Seal
  • Zano
  • zinc monoxide
  • ZINC OXIDE
  • zinc oxide - rubber, paint or pharmaceutical grade
  • Zinc Oxide 2011
  • Zinc Oxide 3000
  • Zinc oxide 99%
  • Zinc oxide 99% - 1ª
  • Zinc oxide 99% - 2ª
  • Zinc oxide 99,9%
  • Zinc oxide 99,9% Gran. Nº 8
  • Zinc oxide 99,9% Pharma
  • ZINC OXIDE 99.8
  • ZINC OXIDE 99.8 - PHARMACEUTICAL GRADE
  • ZINC OXIDE AC
  • Zinc Oxide direct
  • Zinc Oxide EPM
  • Zinc Oxide F80
  • Zinc Oxide FCC
  • Zinc Oxide French Process OXZINAL 802-821
  • Zinc Oxide G6
  • Zinc Oxide Green Seal
  • Zinc oxide Indirect
  • zinc oxide lower grade
  • Zinc Oxide maximum 417W
  • Zinc Oxide maximum 720-946
  • Zinc Oxide maximum 955X
  • Zinc Oxide Nano Tec
  • Zinc Oxide Pharma
  • ZINC OXIDE RAC
  • Zinc Oxide Red Seal
  • Zinc Oxide TG 2000
  • Zinc Oxide While Seal Special
  • Zinc Oxide White Seal
  • Zinc oxide Zinrex 100 C
  • Zinc oxide ZOCO 102
  • Zinc oxide ZOCO 102C
  • Zincoxide
  • Zinkoxid
  • ZINKOXID AC
  • ZINKOXID RAC
  • Zinkoxyd (R) aktiv, Bayoxid (R) aktiv, Bayoxid (R) neutral
  • Zinrex
  • ÓXIDO DE ZINC 99.8 - GRADO FARMACÉUTICO

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 5 studies submitted
  • 4 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [4]
C Form
Nanomaterial (75%), Powder (25%) [4]
C Odour
Odourless (100%) [4]
C Substance type
Inorganic (100%) [4]

Type of Study provided
Studies with data
Key study 2 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 2 studies processed
R Melting / freezing point
1 000 - 1 975 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
1 975 °C

Boiling point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Density

Study results
  • 3 studies submitted
  • 3 studies processed
R Bulk density
5.45 - 5.7 g/cm³ @ 20 °C [1]
R Density
5.47 g/cm³ @ 20 °C [1]
R Relative density
5.68 @ 22 °C [1]

Type of Study provided
Studies with data
Key study 1 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
5.68

Vapour pressure

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Water solubility

Study results
  • 8 studies submitted
  • 5 studies processed
R Water solubility (mass/vol.)
1.1 - 47 mg/L @ 20 °C and pH 6.07 - 7.5 [10]

Type of Study provided
Studies with data
Key study 1 3
Supporting study
Weight of evidence 4
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
1.2 - 2.9 mg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
GHS criteria not met (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Oxidation reduction potential

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

pH

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2 4
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 20.6 µg/L (1)
Intermittent releases (freshwater) -
Marine water 6.1 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 100 µg/L (1)
Sediment (freshwater) 117.8 mg/kg sediment dw (1)
Sediment (marine water) 56.5 mg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 35.6 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 11 studies submitted
  • 9 studies processed
P/RResults
LC50 (4 days) 112 - 8 062 µg/L [25]
LC50 (95 h) 330 µg/L [1]
LC50 (84 h) 23.06 mg/L [1]
EC50 (84 h) 2.065 - 2.066 mg/L [2]

Type of Study provided
Studies with data
Key study 4 5
Supporting study 1
Weight of evidence 1
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 26 studies submitted
  • 12 studies processed
P/RResults
NOEC (2.959 years) 530 µg/L [1]
NOEC (1.808 years) 130 µg/L [1]
NOEC (8 months) 78 - 575 µg/L [4]
NOEC (5 months) 50 - 130 µg/L [2]
NOEC (3.867 months) 56 - 250 µg/L [4]

Type of Study provided
Studies with data
Key study 12
Supporting study 2 3
Weight of evidence
Other 1 8
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 36 studies submitted
  • 23 studies processed
P/RResults
EC50 (4 days) 72 - 103 µg/L [4]
EC50 (48 h) 155 - 100 000 µg/L [20]
EC50 (24 h) 140 - 6 000 µg/L [6]
EC50 (4 h) 1.27 - 1.92 mg/L [2]
LC50 (4 days) 370 - 1 190 µg/L [8]

Type of Study provided
Studies with data
Key study 7 16
Supporting study 5 6
Weight of evidence 1
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 79 studies submitted
  • 58 studies processed
P/RResults
NOEC (9 months) 33.3 - 100 µg/L [2]
NOEC (7 months) 100 µg/L [2]
NOEC (6 months) 100 µg/L [1]
NOEC (3.733 months) 75 µg/L [1]
NOEC (3 months) 300 µg/L [1]

Type of Study provided
Studies with data
Key study 2 56
Supporting study 4
Weight of evidence
Other 17
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 68 studies submitted
  • 30 studies processed
P/RResults
EC50 (4 days) 300 - 1 940 µg/L [4]
EC50 (24 h) 690 - 4 550 µg/L [6]
IC50 (4 days) 1.23 - 6.65 mg/L [8]
IC50 (72 h) 44 - 2 050 µg/L [19]
NOEC (16 days) 1.071 mg/L [1]

Type of Study provided
Studies with data
Key study 9 21
Supporting study 8
Weight of evidence 1
Other 1 28
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Study results
  • 7 studies submitted
  • 1 study processed
P/RResults
NOEC (72 h) 60 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 8 studies submitted
  • 4 studies processed
P/RResults
EC50 (24 h) 7.1 - 27.1 mg/L [12]
EC50 (3 h) 5.2 - 1 000 mg/L [2]
IC50 (4 h) 350 µg/L [1]
NOEC (4 h) 100 µg/L [1]
EC10 (3 h) 720 mg/L [1]

Type of Study provided
Studies with data
Key study 2 2
Supporting study 2 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
100 µg/L

Sediment toxicity

Study results
  • 19 studies submitted
  • 12 studies processed
P/RResults
NOEC (1.055 years) 776 mg/kg sediment dw [1]
NOEC (7 months) 250 mg/kg sediment dw [1]
NOEC (56 days) 850 mg/kg sediment dw [1]
NOEC (42 days) 455 - 1 770 mg/kg sediment dw [5]
NOEC (35 days) 201 - 369 mg/kg sediment dw [2]

Type of Study provided
Studies with data
Key study 1 10
Supporting study 1 3
Weight of evidence 2
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 32 studies submitted
  • 17 studies processed
P/RResults
NOEC (56 days) 199 - 600 mg/kg soil dw [2]
NOEC (42 days) 195 - 1 634 mg/kg soil dw [4]
NOEC (28 days) 100 - 1 000 mg/kg soil dw [12]
NOEC (21 days) 85 - 750 mg/kg soil dw [14]
LOEC (21 days) 750 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 4 15
Supporting study 5
Weight of evidence
Other 8
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 15 studies submitted
  • 14 studies processed
P/RResults
NOEC (42 days) 300 mg/kg soil dw [1]
NOEC (28 days) 32 - 1 000 mg/kg soil dw [17]
EC10 (42 days) 93 mg/kg soil dw [1]
EC10 (28 days) 14.6 - 3 611 mg/kg soil dw [12]
EC50 (28 days) 298 - 5 633 mg/kg soil dw [24]

Type of Study provided
Studies with data
Key study 6 8
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 26 studies submitted
  • 10 studies processed
P/RResults
NOEC (5 months) 100 - 400 mg/kg soil dw [4]
NOEC (67 days) 300 mg/kg soil dw [1]
NOEC (56 days) 200 mg/kg soil dw [2]
NOEC (48 days) 33 mg/kg soil dw [1]
NOEC (45 days) 100 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 8 10
Supporting study 4
Weight of evidence 2
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 38 studies submitted
  • 35 studies processed
P/RResults
NOEC (6.067 months) 500 mg/kg soil dw [1]
NOEC (84 days) 17 - 200 mg/kg soil dw [5]
NOEC (63 days) 80 mg/kg soil dw [1]
NOEC (55 days) 50 - 150 mg/kg soil dw [4]
NOEC (52 days) 162 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1 35
Supporting study 1
Weight of evidence 1
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 5 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 500 µg/m³ repeated dose toxicity
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 83 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.5 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 83 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 830 µg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 18 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 16
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 5
Supporting study 7
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 8 studies submitted
  • 4 studies processed
P/RResults
LD50 2 000 - 5 000 mg/kg bw (rat) [2]
LD50 2 000 - 5 000 mg/kg bw (mouse) [3]
M/CInterpretations of results
Practically nontoxic [1]

Type of Study provided
oral
Studies with data
Key study 4
Supporting study 3 1
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 8 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 h) 1.79 - 5.7 mg/L air (rat) [2]
M/CInterpretations of results
Study cannot be used for classification [1]

inhalation
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
other routes
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 3
Weight of evidence 1
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5 700 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 5
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 7 studies submitted
  • 3 studies processed
P/RResults
NOAEL (rat): 31.52 mg/kg bw/day [1]
NOEL (rat): 3 000 ppm [1]
NOEL (mouse): 3 000 ppm [1]

Type of Study provided
Study data: oral
Studies with data
Key study 3
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 9 studies submitted
  • 3 studies processed
P/RResults
NOAEL (rat): 1.5 mg/m³ air [2]
NOAEC (rat): 500 µg/m³ air [1]

Study data: inhalation
Studies with data
Key study 3
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 1 study processed
P/RResults
LOAEL (rat): 75 mg/kg bw/day [1]

Study data: dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route - systemic effects:
Adverse effect observed NOAEL 13.3 mg/kg bw/day (subchronic, rat)
Dermal route - systemic effects:
Adverse effect observed LOAEL 75 mg/kg bw/day (subacute, rat)
Inhalation route - local effects:
Adverse effect observed NOAEC 1.5 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 25 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 12
Supporting study 13
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1 4
Supporting study 2 2
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on developmental toxicity
Inhalation route:
No adverse effect observed NOAEC 7.5 mg/m³ (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant