Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Nickel monoxide
  • IUPAC name: oxonickel
  • Other names
EC / List no.:
215-215-7
CAS no.:
1313-99-1
Index number:
028-003-00-2
Molecular formula:
NiO
SMILES:
O=[Ni]
InChI:
InChI=1S/Ni.O
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
37
Of which contain:
8 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may cause cancer by inhalation, causes damage to organs through prolonged or repeated exposure, may cause long lasting harmful effects to aquatic life and may cause an allergic skin reaction.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is fatal if inhaled, may cause cancer, is toxic to aquatic life with long lasting effects, is toxic to aquatic life, may damage fertility or the unborn child, is harmful if swallowed, causes serious eye irritation, is suspected of causing genetic defects, may cause allergy or asthma symptoms or breathing difficulties if inhaled and causes skin irritation.

Breakdown of all 1378 C&L notifications submitted to ECHA

Skin Sens. 1 H317 Harmonised Classification
STOT RE 1 H372 Harmonised Classification
Carc. 1A H350i Harmonised Classification
Aquatic Chronic 4 H413 Harmonised Classification
Resp. Sens. 1 H334
Aquatic Acute 2 H401
Aquatic Chronic 2 H411
Acute Tox. 4 H332
Acute Tox. 2 H330
Repr. 1B H360
Acute Tox. 4 H302
Eye Irrit. 2 H319
Muta. 2 H341
Skin Irrit. 2 H315
Carc. 1B H350
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • C
  • R
  • Ss
  • Sr

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 57 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 - 10 000 tonnes per year.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), production of mixtures or articles by tabletting, compression, extrusion or pelletisation, open transfer and processing with minerals/metals at elevated temperature and hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting).

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, manufacturing of the substance, as processing aid, formulation in materials, in the production of articles, industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and vehicles covered by End of Life Vehicles (ELV) directive (e.g. personal vehicles or delivery vans).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: closed, continuous processes with occasional controlled exposure, transfer of chemicals at dedicated facilities and handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders).

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following products: pH regulators and water treatment products and laboratory chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens) and high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding).

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and formulation in materials.

This substance is used in the following products: metal surface treatment products, metals, pH regulators and water treatment products and laboratory chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals, mineral products (e.g. plasters, cement), metals and electrical, electronic and optical equipment.

This substance is used in the following activities or processes at workplace: transfer of chemicals, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), closed batch processing in synthesis or formulation, transfer of substance into small containers, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders), closed processes with no likelihood of exposure, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and manual maintenance (cleaning and repair) of machinery.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, in the production of articles, as processing aid and manufacturing of the substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, formulation in materials and formulation of mixtures.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • A.M.P.E.R.E. ALLOYS, 12 Mail Joliot Curie 95310 SAINT-OUEN-L'AUMONE VAL D'OISE France
  • A.M.P.I.S.r.l., Strada Anulare Torre 4 20090 San Felice - Segrate Milan Italy
  • Advanced Refining Technologies GmbH, In der Hollerhecke 1 67547 Worms Germany
  • ALBEMARLE CATALYSTS COMPANY B.V., Nieuwendammerkade 1-3 PO Box 37650 1030 BE Amsterdam Netherlands
  • Avantor Performance Materials Poland S.A., Sowińskiego 11 44-100 Gliwice Poland
  • AXENS SA, 89, boulevard Franklin Roosevelt B.P. 50802 F-92508 Rueil-Malmaison Cedex France France
  • BASF Nederland B.V., Groningensingel 1 Postbus 1019 6801 MC Arnhem Netherlands
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Bootman Chemical Safety Ltd, Diss Business Centre IP214HD Diss Norfolk United Kingdom
  • Cambridge Environmental Assessments part of RSK ADAS Ltd, Battlegate Road Boxworth CB23 4NN Cambridge Cambridgeshire United Kingdom
  • CATALYST RECOVERY EUROPE S.A., 420, Route de Longwy 4832 Rodange Luxembourg
  • Chemieservice Dr. Stoeber (N), Kefersteinstrasse 6 D-06110 Halle Germany
  • Chemservice S.A. (H5P7), 5, an de Laengten 6776 Grevenmacher Luxembourg
  • Chevron Phillips Chemicals International N.V. - OR CPC, Airport Plaza, Stockholm Building Da Vincilaan 19 1831 Diegem Belgium
  • Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1 65843 Sulzbach am Taunus Germany
  • colorobbia italia spa, via Pietramarina 53 via Pietamarina 123 50053 Sovigliana - Vinci Firenze Italy
  • CRI Catalyst Company Belgium NV, Ringvaartweg-Wondelgem, 4 B-9032 Wondelgem Belgium
  • CRI Catalyst Leuna GmbH, Gebaude 8322 Am Haupttor D-06237 Leuna Leuna Germany
  • DHI (OR17), Agern Allé 5 2970 Horsholm Denmark
  • Envigo Research Limited 24, Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom
  • EPCOS OHG, Siemensstrasse 43 8530 Deutschlandsberg Austria
  • Eurecat Deutschland GmbH, Tricatstrasse 06803 Bitterfeld-Wolfen Saxonia-Anhalt Germany
  • EURECAT FRANCE SAS, 121 ave Marie Curie ZI Jean Jaurès 07800 La Voulte sur Rhône France
  • Euro Support Manufacturing Czechia, s.r.o., Záluží 1 436 70 Litvínov Czech Republic
  • Evonik Degussa GmbH, Rellinghauser Strasse 1 - 11 C-ES 45128 Essen North Rhine-Westfalia Germany
  • Ferro (Great Britain) Limited, Nile Street Burslem ST6 2BQ Stoke-on-Trent United Kingdom
  • Ferro Spain S.A., Carretera Valencia - Barcelona Km 61.5 12550 Almazora (Castellon) Spain
  • G.Vogler BV, Cornusbaan 91 2908 KB Capelle aan den IJssel SELECT Netherlands
  • GE thermometrics (UK) Limited, CROWN INDUSTRIAL ESTATE, PRIORSWOOD ROAD TA2 8QY Taunton SOMERSET United Kingdom
  • Glencore Nikkelverk AS, Vesterveien 31 4606 Kristiansand Norway
  • GRACE GmbH, In der Hollerhecke 1 67545 Worms Germany
  • GRACE GmbH (OR 4), In der Hollerhecke 1 67547 Worms Germany
  • H.C. Starck Smelting GmbH & Co. KG, Im Schleeke 78 -91 38642 Goslar Germany
  • H.C. Starck Tungsten GmbH, Landsberger Str. 98 80339 München Germany
  • Haldor Topsoe A/S, Nymøllevej 50 DK28000 Lyngby Denmark
  • Hellenic Petroleum S.A., 8Α Chimarras st. GR 15125 Maroussi Attica Greece
  • INEOS Sales (UK) Ltd, Hawkslease Chapel lane SO437FG Lyndhurst Hants United Kingdom
  • Instytut Nowych Syntez Chemicznych, Aleja Tysiąclecia Państwa Polskiego 13A 24-110 Puławy Poland
  • Jemmtec Ltd T/A Magma Ceramics, Low Road Earlsheaton WF12 8BU Dewsbury W Yorks United Kingdom
  • Johnson Matthey Chemicals GmbH, Wardstrasse 17 D-46446 Emmerich am Rhein Germany
  • Johnson Matthey PLC, 5th Floor, 25 Farringdon Street EC4A 4AB London United Kingdom
  • Luxcontrol S.A. (OR69), 1, Avenue des Terres Rouges 4331 Esch sur Alzette Luxembourg
  • Nickelhütte Aue GmbH, Rudolf-Breitscheid-Straße 65-75 D-08280 Aue Germany
  • RANIDO, Thákurova 531/4 16000 Praha 6 Czech Republic
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • Rivendell International, Rivendell House Co. Meath Stamullen Ireland
  • Rivendell International, Rivendell House Co. Meath Stamullen Co. Meath Ireland
  • Sinopec Europa GmbH, Messe Turm Friedrich-Ebert-Anlage 49 60308 Frankfurt am Main Germany
  • TODINI AND CO. SPA, Corso Milano 46 B 20900 MONZA ITALIA Italy
  • Todini GmbH, Dr. Alfred-Herrhausen-Allee 12 47228 Duisburg Germany
  • TSGE, Concordia House, St James Business Park Grimbald Crag Court HG5 8QB Knaresborough North Yorkshire United Kingdom
  • Umicore NV/SA, Rue du Marais 31 1000 Brussels Belgium
  • Univar BV, Schouwburgplein 30-34 NL-3012 CL Rotterdam Netherlands
  • UOP B.V.B.A., Noorderlaan 147 B-2030 Antwerp Belgium
  • Vale Europe Limited, Acton Refinery Bashley Road NW10 6SN London GB United Kingdom
  • Vale Japan Limited, Acton Refinery Bashley Road NW10 6SN London GB United Kingdom
  • INCO Industria Colori spa, via Montebonello 19/21 41026 Pavullo n/F (MO) Italy
  • INEOS Commercial Services UK Ltd, Hawkslease Chapel Lane SO437FG Lyndhurst Hampshire United Kingdom
  • knoell Germany – OR – A1, Konrad-Zuse-Ring 25 68163 Mannheim Germany
  • REPSOL S.A., Méndez Álvaro, 44 28045 Madrid Madrid Spain

Other names

  • -
  • Nickel (2+) oxide
  • Nickel (II) oxide
  • Nickel Monooxide
  • Nickel monoxide
  • NICKEL OXIDE
  • nickel(II) oxide
  • Nickel(II)oxide
  • Nickelmonoxid
  • Nickeloxide
  • Oxonickel
  • Ammonia decomposition catalyst
  • Black Nickel Oxide
  • Conc 1
  • DER
  • DS071
  • FMW
  • Green Nickel Oxide
  • Green Nickel oxide powder
  • Melting Base Nickel
  • NF-733DFS
  • nichel monoxide
  • Nickel monoxide
  • Nickel Oxide
  • Nickel Oxide Powder
  • Nickel Oxide Reaction Mass
  • Nickel Oxide Sinter
  • Nickel Powder
  • Nickel Sinter
  • Nickel(II) Oxide Green
  • Nickelconcentrate
  • NS-733D
  • NS-733DF
  • Oxido de Niquel
  • Oxido de Niquel Sinterizado
  • Reaction Mass Containing Nickel Oxide
  • Sinter
  • Sinter 75
  • Specialyst®
  • substance only available in mixtures

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
1 955 - 2 090 °C [3]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 1 study submitted
  • 1 study processed
R Relative density
6.75 @ 21 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
6.75

Vapour pressure

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 2 studies submitted
  • 2 studies processed
R Water solubility (mass/vol.)
35.2 - 2 260 µg/L @ 20 °C and pH 6.4 - 7.4 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
35.2 µg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 136 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 45 1
Supporting study 51 1
Weight of evidence
Other 28 10
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 54 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 11
Supporting study 26 1 3
Weight of evidence
Other 13
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 40 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 19 7 1
Supporting study 3
Weight of evidence
Other 10
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 7.1 µg/L (1)
Intermittent releases (freshwater) 0 ng/L (1)
Marine water 8.6 µg/L (1)
Intermittent releases (marine water) 0 ng/L (1)
Sewage treatment plant (STP) 330 µg/L (1)
Sediment (freshwater) 109 mg/kg sediment dw (1)
Sediment (marine water) 109 mg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 29.9 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning 120 µg/kg food (1)

Short–term toxicity to fish

Study results
  • 125 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 15.3 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 61 1
Weight of evidence
Other 9 53
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 30 studies submitted
  • 6 studies processed
P/RResults
NOEC (32 days) 35 - 431 000 µg/L [11]
NOEC (30 days) 108.9 µg/L [1]
NOEC (8 days) 40 - 80 µg/L [2]
LOEC (32 days) 35 - 3 730 µg/L [11]
LOEC (30 days) 433.5 µg/L [1]

Type of Study provided
Studies with data
Key study 7
Supporting study 6 1
Weight of evidence
Other 10 6
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 160 studies submitted
  • 4 studies processed
P/RResults
LC50 (48 h) 13 - 276 µg/L [17]

Type of Study provided
Studies with data
Key study 4
Supporting study 75 12
Weight of evidence
Other 24 45
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 83 studies submitted
  • 24 studies processed
P/RResults
NOEC (8 months) 66 µg/L [1]
NOEC (4.233 months) 713 µg/L [1]
NOEC (56 days) 40 - 120 µg/L [2]
NOEC (42 days) 40 µg/L [2]
NOEC (36 days) 61 µg/L [1]

Type of Study provided
Studies with data
Key study 21 4
Supporting study 35
Weight of evidence
Other 17 6
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 86 studies submitted
  • 16 studies processed
P/RResults
EC50 (72 h) 40.7 - 1 430 µg/L [26]
IC50 (48 h) 456 - 4 400 µg/L [3]
NOEC (72 h) 3.5 - 5 476.8 µg/L [26]
NOEC (48 h) 10 - 110.5 µg/L [2]
LOEC (72 h) 6.2 - 11 551.3 µg/L [26]

Type of Study provided
Studies with data
Key study 5 11
Supporting study 22 2
Weight of evidence
Other 19 27
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Study results
  • 30 studies submitted
  • 1 study processed
P/RResults
EC50 (7 days) 87 - 1 377 µg/L [6]
EC10 (7 days) 3.9 - 435.3 µg/L [6]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 7
Weight of evidence
Other 2 19
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 59 studies submitted
  • 1 study processed
P/RResults
EC50 (30 min) 33 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 19
Weight of evidence
Other 3 36
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 50 studies submitted
  • 25 studies processed
P/RResults
NOEC (4 days) 900 µg/L [1]
LOEC (4 days) 1.8 mg/L [1]
EC10 (56 days) 762 - 1 625 mg/kg sediment dw [2]
EC10 (49 days) 210 - 339 mg/kg sediment dw [3]
EC10 (42 days) 160 - 3 307 mg/kg sediment dw [4]

Type of Study provided
Studies with data
Key study 12
Supporting study 6
Weight of evidence 17
Other 11 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 39 studies submitted
  • 6 studies processed
P/RResults
NOEC (42 days) 20 - 180 mg/kg soil dw [4]
NOEC (28 days) 100 - 700 mg/kg soil dw [3]
NOEC (21 days) 180 - 800 mg/kg soil dw [4]
LOEC (42 days) 320 mg/kg soil dw [1]
LOEC (28 days) 300 - 1 000 mg/kg soil dw [3]

Type of Study provided
Studies with data
Key study 6
Supporting study 10 2 1
Weight of evidence
Other 13 7
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 18 studies submitted
  • 3 studies processed
P/RResults
NOEC (28 days) 36.4 - 1 140 mg/kg soil dw [2]
LOEC (28 days) 560 mg/kg soil dw [1]
EC50 (28 days) 476 mg/kg soil dw [1]
LC50 (8.167 months) 8 351 mg/kg diet [1]
LC50 (28 days) 1 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other 7 5
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 223 studies submitted
  • 14 studies processed
P/RResults
NOEC (63 days) 29 - 355 mg/kg soil dw [4]
NOEC (60 days) 88 - 187 mg/kg soil dw [2]
NOEC (56 days) 17 - 69 mg/kg soil dw [3]
NOEC (40 days) 67 mg/kg soil dw [1]
NOEC (30 days) 13 - 187 mg/kg soil dw [4]

Type of Study provided
Studies with data
Key study 14
Supporting study 40
Weight of evidence
Other 75 94
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 37 studies submitted
  • 23 studies processed
P/RResults
NOEC (8.975 years) 86 mg/kg soil dw [2]
NOEC (1.381 years) 59 - 94 mg/kg soil dw [3]
NOEC (28 days) 41 mg/kg soil dw [1]
NOEC (7 days) 30 - 770 mg/kg soil dw [13]
EC10 (1.573 years) 295 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 23
Supporting study 4
Weight of evidence
Other 5 5
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 9 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study 2
Weight of evidence
Other 1 3
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 50 µg/m³ developmental toxicity / teratogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 50 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 18.9 mg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 12 µg/cm² sensitisation (skin)
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 60 ng/m³ developmental toxicity / teratogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 60 ng/m³ repeated dose toxicity
Acute /short term: (DNEL) 1.8 mg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 11 µg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: (DNEL) 370 µg/kg bw/day acute toxicity
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 21 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study 14
Weight of evidence 3
Other 2
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 7 studies submitted
  • 5 studies processed
P/RResults
LD50 5 000 - 11 000 mg/kg bw (rat) [8]
M/CInterpretations of results
Not classified [4]

Type of Study provided
oral
Studies with data
Key study 5
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
inhalation
  • 10 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 h) 5.08 - 5.15 mg/L air (rat) [2]
M/CInterpretations of results
Other [2]

inhalation
Studies with data
Key study 3
Supporting study 4 1
Weight of evidence 1
Other 1
Data waiving
no waivers
dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
other routes
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 1 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 1
Weight of evidence 1
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 2
Data waiving
no waivers
Study data: inhalation
  • 19 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study 4
Supporting study 13
Weight of evidence
Other 2
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 1
Supporting study 7
Weight of evidence 4
Other 2
Data waiving
no waivers
Study data: in vivo
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence 1
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 15 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2 1
Supporting study 4 1
Weight of evidence 4
Other 3
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study 1 2
Weight of evidence
Other 3
Data waiving
no waivers
Study data: developmental
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study 1 2
Weight of evidence 1
Other 1
Data waiving
no waivers
Study data: other studies
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 1
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant