Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Bis(2-ethylhexyl) adipate
  • IUPAC name: 1,6-bis(2-ethylhexyl) hexanedioate
  • Other names
EC / List no.:
203-090-1
CAS no.:
103-23-1
Index number:
Molecular formula:
C22H42O4
SMILES:
CCCCC(CC)COC(=O)CCCCC(=O)OCC(CC)CCCC
InChI:
InChI=1/C22H42O4/c1-5-9-13-19(7-3)17-25-21(23)15-11-12-16-22(24)26-18-20(8-4)14-10-6-2/h19-20H,5-18H2,1-4H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
25
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.
According to the majority of notifications provided by companies to ECHA in CLP notifications no hazards have been classified.

Breakdown of all 1585 C&L notifications submitted to ECHA

Not Classified
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Eye Irrit. 2 H319
Skin Irrit. 2 H315
Aquatic Chronic 2 H411
Acute Tox. 4 H302
Acute Tox. 4 H332
Carc. 2 H351
Repr. 2 H361
Aquatic Chronic 4 H413
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 39 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Substance included in the Community Rolling Action Plan (CoRAP).
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 10 000 - 100 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: washing & cleaning products, lubricants and greases, plant protection products, adhesives and sealants, polishes and waxes and coating products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and closed processes with no likelihood of exposure.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and vehicles. This substance can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones), rubber (e.g. tyres, shoes, toys), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper) and fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).

This substance is used in the following products: washing & cleaning products, polishes and waxes and plant protection products.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: roller or brushing applications, transfer of chemicals, non-industrial spraying, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: polymers, lubricants and greases, metal working fluids, inks and toners, hydraulic fluids and coating products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, transfer of substance into small containers, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, production of mixtures or articles by tabletting, compression, extrusion or pelletisation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: washing & cleaning products, metal surface treatment products, polymers, textile treatment products and dyes, lubricants and greases and pH regulators and water treatment products.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure, industrial spraying, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, roller or brushing applications, transfer of substance into small containers and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, laboratory work, transfer of substance into small containers and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • A.&A. F.lli Parodi spa, Via Paleocapa 7 Italy 20121 Milano MI Italy
  • Anthesis (Ireland) Limited 20, The Black Church St Mary's Place D07 P4AX Dublin Ireland
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Boryszew S.A. Oddzial Boryszew ERG w Sochaczewie, 15-go Sierpnia 106 96-500 Sochaczew Mazowsze Poland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre HW77 D02 Dublin Ireland
  • COIM SpA, Via Manzoni 28/32 20019 Settimo Milanese (MI) Italy
  • Condensia Quimica SA, C/ Junqueras, 16-11-A 08003 Barcelona Spain
  • Croda Nederland BV, Buurtje 1 2802 BE Gouda Netherlands
  • CS Regulatory Ltd 1L-26, The Old Courthouse St Peters Churchyard DE1 1NN Derby United Kingdom
  • Daedong System Poland, ul. Mała Łąka 28/32 43-400 Cieszyn Poland
  • DEZA a.s., Masarykova 753 75701 Valasske Mezirici Czech Republic
  • Domus Chemicals S.p.A, v. Mazzini 1 24066 Pedrengo Bergamo Italy
  • Eastman Chemical B.V., Watermanweg 70 3067 GG Rotterdam Netherlands
  • EIGENMANN & VERONELLI S.p.A., via della Mosa, 6 20017 Rho (MI) Italy
  • Envigo Research Limited 109, Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom
  • FACI METALEST S.L.U., C/F Oeste Parcela, 54 – Poligono Malpica Sta Isabel 50016 Zaragoza Spain
  • Grupa Azoty Zakłady Azotowe Kędzierzyn Spółka Akcyjna, skr. poczt. 163 ul. Mostowa 30A 47-220 Kędzierzyn-Kożle Poland
  • HH Compliance Ltd, Rubicon Centre C.I.T. Campus T12 Y275 Bishopstown Cork Ireland
  • INDUSTRIAL QUIMICA LASEM, S.A.U., Avda. de la Industria,7 08297 Castellgali Spain
  • KTR Europe GmbH, Mergenthalerallee 77 65760 Eschborn Germany
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • Lubrizol Limited, The Knowle, Nether Lane Hazelwwod DE56 4AN Derby Derbyshire United Kingdom
  • Maisons du Monde France SAS, Le Portereau - BP52402 44124 VERTOU CEDEX France
  • Murata Electronics Europe B.V., Wegalaan 2 2132 JC Hoofddorp Netherlands
  • NYCO-STPC, Zoning Industriel de Tournai Ouest 1 B-7503 Froyennes Belgium
  • POLYNT S.p.A., via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman,6 Box 5 B-1040 Brussels Belgium
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brussels Belgium
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SO.G.I.S. Industria Chimica S.p.A., Via Giuseppina, 132 26048 Sospiro (CR) Italy
  • STEARINERIE DUBOIS, Scoury 36300 CIRON France
  • Teknor Apex BV, Mijnweg 1 Mijnweg 1, (P.O.Box 601, 6160 AP) 6167AC Geleen Please select Netherlands
  • TEMIX OLEO S.R.L., VIA PIERO PORTALUPPI 17 20138 MILANO Italy
  • TRAQUISA, Circunvalación, 27 08210 Barbera del Valles Barcelona Spain
  • TÜV SÜD Iberia S.A.U. (051), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • VALTRIS ENTERPRISES FRANCE, ZI Baleycourt 55103 VERDUN FRANCE France
  • wspuk17, WSP House 70 Chancery Lane WC2A 1AF London United Kingdom
  • ZSCHIMMER & SCHWARZ ITALIANA S.p.A., Via Angelo Ariotto No. 1 13038 TRICERRO (VERCELLI) Italy
  • OXEA Nederland BV, Hornweg 10 1045 AR Amsterdam Netherlands

Other names

  • -
  • 1,6-bis(2-ethylhexyl) hexanedioate
  • 1,6-bis(2-ethylhexyl) hexanedioate; adipic acid di(2-ethylhexyl) ester
  • Adipic acid di(2-ethylhexyl) ester
  • Bis (2-ethylhexyl) adipate
  • Bis (2-ethylhexyl) adipateBis(2-ethylhexyl) adipatebis(2-ethylhexyl) hexanedioate
  • Bis(2-ethylhexyl) Adipate
  • Bis(2-ethylhexyl) hexanedioate
  • Bis(2-ethylhexyl)adipat
  • DEHA, DOA
  • Dioctyl adipate
  • Diottile adipato (DOA)
  • Hexanedioc acid bis (2-ethylhexyl) ester
  • LINCOL DOA
  • Oxsoft DOA
  • Plasticizer DOA
  • Bis(2-ethylhexyl) adipate
  • Adimoll DO
  • Adipic acid, bis(2-ethylhexyl) ester (6CI, 7CI, 8CI)
  • Adipinsäure- bis(2-ethylhexyl)ester
  • Adipol 2EH
  • Bis(2-ethylhexyl) adipate
  • bis(2-ethylhexyl) adipát
  • Bis-2-ethylhexyl adipate
  • Bis-2-ethylhexyladipat
  • Bisoflex DOA
  • DEHA
  • Dermol DOA
  • Di(2-ethylhexyl) adipate
  • Di(2-ethylhexyl)-adipat
  • Di-octyl-adipat
  • Diethylhexyl adipate
  • Diisooctyladipat
  • DIOCTYL ADIPATE
  • Dioctyladipat
  • dioktyl adipát
  • DIPLAST D
  • DIPLAST D/MG
  • DOA
  • DOCOIL DOA
  • DUB DOA
  • DUB Green DOA
  • Effomoll DA
  • Effomoll DOA
  • Ergoplast AdDO
  • Ergoplast ADO
  • Flexol A 26
  • Hexanedioic acid, bis(2-ethylhexyl) ester (9CI)
  • Jayflex DOA 2
  • Kodaflex DOA
  • Lankroflex DOA
  • Monoplex DOA
  • Octyl adipate
  • Oxsoft DOA
  • Paryol DOA
  • Plastomoll DOA
  • Reomol DOA
  • Sansocizer DOA
  • Sicol 250
  • Truflex DOA
  • Vestinol OA
  • Wickenol 158
  • Witamol 320

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Odour
Slight (100%) [1]
C Substance type
Organic (100%) [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-67.8 °C

Boiling point

Study results
  • 3 studies submitted
  • 1 study processed
R Boiling point
377.88 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
377.88 °C

Density

Study results
  • 2 studies submitted
  • 1 study processed
R Density
0.92 g/cm³ @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.925

Vapour pressure

Study results
  • 2 studies submitted
  • 1 study processed
R Vapour pressure
0 Pa @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 20 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
8.94 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
8.94 @ 25 °C

Water solubility

Study results
  • 2 studies submitted
  • 2 studies processed
R Water solubility (mass/vol.)
3.2 - 100 µg/L @ 22 - 25 °C and pH 7 [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
3.2 µg/L @ 22 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 3 studies submitted
  • 3 studies processed
R Flash point
196 - 206 °C @ 101.3 - 101.325 kPa [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
196 °C

Auto flammability

Study results
  • 3 studies submitted
  • 3 studies processed
R Autoflammability / self-ignition
340 - 377 °C @ 101.3 - 101.325 kPa [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
377 °C

Flammability

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 4
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 3 studies submitted
  • 2 studies processed
R dynamic viscosity (in mPa s)
13 - 13.7 [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
13.7 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 3 studies submitted
  • 1 study processed
R Dissipation half life (DT50)
15.19 h [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
15.19 h
Degradation rate constant with OH radicals
0 cm³ molecule-1 d-1

Hydrolysis

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 12 studies submitted
  • 1 study processed
R BOD5
277 mg O2/g test material [1]
R COD
1.687 g O2/g test material [1]
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 7 1 3
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 4 4
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
27 L/kg ww

Bioaccumulation: terrestrial

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
36 308

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
5.23 Pa m³/mol @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Study results
  • 1 study submitted
  • 1 study processed
% Distribution in Media:
R Air 0.088 % [1]
R Water 0 % [1]
R Soil 97.3 % [1]
R Sediment 2.16 % [1]
R Suspended sediment 0.068 % [1]
R Biota 0.005 % [1]
R Aerosol 0.354 % [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 865 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 780 µg/L [1]
LC0 (4 days) 780 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
EC50 (48 h) 500 mg/L [1]
EC0 (48 h) 250 mg/L [1]
EC100 (48 h) 500 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 770 µg/L [1]
LOEC (21 days) 770 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 500 mg/L [1]
EC20 (72 h) 398.6 mg/L [1]
EC100 (72 h) 500 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (3 h) 350 mg/L [1]
NOEC (3 h) 350 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (14 days) 550 mg/kg soil dw [1]
LC50 (14 days) 865 mg/kg soil dw [1]
LC50 (7 days) 1 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
865 mg/kg soil dw

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 17.8 mg/m³ effect on fertility
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 25.5 mg/kg bw/day effect on fertility
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.4 mg/m³ effect on fertility
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 13 mg/kg bw/day effect on fertility
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.7 mg/kg bw/day effect on fertility
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 3
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 5 studies submitted
  • 1 study processed
P/RResults
LD50 20 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Practically nontoxic [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 h) 5.7 mg/L air (rat) [1]
M/CInterpretations of results
Practically nontoxic [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 20 000 mg/kg bw
Inhalation route:
No adverse effect observed Discriminating conc. 5 700 mg/m³

Irritation / corrosion

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence 2 1
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 8 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 200 mg/kg bw/day [1]
NOAEL (rat): 12 000 ppm [1]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other 1 1
Data waiving
no waivers
Study data: inhalation
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant