Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
200-580-7
CAS no.:
64-19-7
Index number:
Molecular formula:
C2H4O2
SMILES:
CC(O)=O
InChI:
InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
43
Of which contain:
3 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance causes severe skin burns and eye damage and is a flammable liquid and vapour.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye damage.

Breakdown of all 4831 C&L notifications submitted to ECHA

Flam. Liq. 3 H226 Harmonised Classification
Skin Corr. 1A H314 Harmonised Classification
Eye Dam. 1 H318
Acute Tox. 4 H312
Acute Tox. 4 H332
Met. Corr. 1 H290
STOT SE 3 H335
Aquatic Chronic 3 H412
Skin Corr. 1 H314
Skin Corr. 1B H314
STOT SE 1 H370
Not Classified
Skin Corr. 1C H314
Acute Tox. 4 H302
Eye Irrit. 2 H319
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 149 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:
There are 0 authorised Biocidal Product(s) that use this substance as an active ingredient

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 000 - 10 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is approved in the EEA and/or Switzerland for use in biocidal products more favourable for the environment, human or animal health. It is an authorised food additive.

This substance is used in the following products: coating products, washing & cleaning products, air care products, lubricants and greases, fillers, putties, plasters, modelling clay, anti-freeze products, fertilisers, plant protection products, finger paints, biocides (e.g. disinfectants, pest control products), welding & soldering products and textile treatment products and dyes.

Other release to the environment of this substance is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

This substance is used in the following activities or processes at workplace: transfer of chemicals, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, calendering operations, industrial spraying, transfer of substance into small containers, roller or brushing applications, production of mixtures or articles by tabletting, compression, extrusion or pelletisation and laboratory work.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture) and wood (e.g. floors, furniture, toys).

This substance is used in the following products: laboratory chemicals, pH regulators and water treatment products, water treatment chemicals, plant protection products, washing & cleaning products, coating products and fertilisers.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, batch processing in synthesis or formulation with opportunity for exposure, closed processes with no likelihood of exposure, treatment of articles by dipping and pouring, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, non-industrial spraying and roller or brushing applications.

Other release to the environment of this substance is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

This substance is used in the following products: coating products, perfumes and fragrances, textile treatment products and dyes, paper chemicals and dyes and polymers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, laboratory work, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials, manufacturing of the substance, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid, of substances in closed systems with minimal release and in the production of articles.

This substance is used in the following products: laboratory chemicals, oil and gas exploration or production products, washing & cleaning products, water treatment chemicals, polymers, coating products and pH regulators and water treatment products.

This substance is used in the following areas: mining and formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals, textile, leather or fur, wood and wood products and pulp, paper and paper products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, laboratory work and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and manufacturing of the substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, laboratory work, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, formulation in materials, as processing aid, for thermoplastic manufacture, as processing aid, of substances in closed systems with minimal release and in the production of articles.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use explosion-proof equipment (electrical/ventilating/lighting/etc.); wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Abbott Diagnostics GmbH, Max Planck Ring 2 D-65205 Delkenheim Germany
  • Acetex Intermediates S.A.S., 6, rue Jean Jaurès F-92807 Puteaux France
  • ACETIFICIO SCALIGERO S.A.S. DI RANGHIERO PAOLO & C., Via Strà,2 37044 Cologna Veneta VR Italy
  • ACETUM SpA, Via pertini 440 41032 Cavezzo Italy
  • Archroma Germany GmbH, Kasteler Str. 45 65203 Wiesbaden Germany
  • ARCHROMA IBÉRICA, S.L., ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain
  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • AVANTOR PERFORMANCE MATERIALS POLAND SPÓŁKA AKCYJNA, Sowińskiego 11 44-101 Gliwice Silesia Poland
  • AXXENCE Aromatic GmbH, Tackenweide 28 46446 Emmerich am Rhein NRW Germany
  • B-Lands Consulting (811725-2), 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
  • BASF Colors & Effects GmbH, An der Rheinschanze 1 67059 Ludwigshafen Germany
  • BASF Personal Care and Nutrition GmbH, Henkelstr. 67 40589 Düsseldorf Germany
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Bayer AG, Kaiser-Wilhelm-Allee 51373 Leverkusen Germany
  • Bayer Hispania S.L., Pau Claris, 196 08037 Barcelona Spain
  • BENS CONSULTING, kemijsko svetovanje, d.o.o., Bakovniška 7 1241 Kamnik Slovenia
  • Berner Ltd, Hitsaajankatu 24 00810 Helsinki Finland
  • Bollig & Kemper GmbH & Co. KG, Vitalisstraße 114 D-50827 Köln Germany
  • BP Chemicals Ltd, Chertsey Rd TW16 7BP Sunbury on Thames Middlesex United Kingdom
  • Briar Chemicals Limited, 5 Fleet Place EC4M 7RD London United Kingdom
  • CABB Oy (OR of CABB AG), Kemirantie 1 P.O.Box 566 Kokkola Finland
  • Cantel Medical (Italy) S.r.l., Via Laurentina 169 00071 Pomezia (RM) Italy
  • CARBOCHEM SRL, VIA B. MILANI 21043 CASTIGLIONE OLONA VARESE Italy
  • Celanese Europe BV, The New Atrium Strawinskylaan 3105 1077 ZX Amsterdam Netherlands
  • Celanese Production Belgium BVBA, Industrieweg 80 B-3620 Lanaken Belgium
  • Celanese Production Germany GmbH & Co. KG, Am Unisys-Park 1 65843 Sulzbach Germany
  • ChampionX Europe B.V., Oude Rhijnhofweg 17 NL-2342BB Oegstgeest Oegstgeest Netherlands
  • ChAR Consultancy EOOD, Kırdjali bulvard Bulgaria 37, blok 51 6600 Kırdjali Kırdjali Bulgaria
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland
  • Chemring Nobel AS, High Energy Materials, Engeneveien 7 N-3475 SAETRE Norway
  • Chemsafe srl, Via Ribes 5 10010 Colleretto Giacosa (TO) Italy
  • Chemservice GmbH - (Q1Z2), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Clariant Plastics & Coatings (Deutschland) GmbH, Brüningstrasse 50 65929 Frankfurt am Main Germany
  • Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1 65843 Sulzbach am Taunus Germany
  • CS Regulatory Ltd 1L-11, The Old Courthouse St Peters Churchyard DE1 1NN Derby Derbyshire United Kingdom
  • De Burg BV, Marconistraat 26 1704RG Heerhugowaard Netherlands
  • DeSangosse Ltd, Hillside Mill Quarry Lane CB25 0LU Swaffham Bulbeck Cambridge United Kingdom
  • Dow Benelux B.V. OR-51, Postbus 48 4530 AA Terneuzen Netherlands
  • Dow France SAS, 23 Avenue Jules Rimet 93200 La Plaine Saint Denis France
  • Dr. Paul Lohmann GmbH & Co. KGaA, Hauptstraße 2 31860 Emmerthal Germany
  • DSM Nutritional Products GmbH, Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany
  • DuPont Nutrition Biosciences ApS, Langebrogade 1 DK-1001 Copenhagen Denmark
  • DyStar Colours Distribution GmbH, Am Prime-Parc 12 65479 Raunheim Germany
  • Eastman Chemical B.V., Watermanweg 70 3067 GG Rotterdam Netherlands
  • ENDURA S.p.A., Viale Pietramellara, 5 40121 Bologna Italy
  • ERNESTO VENTOS, S.A., Carretera Reial 120B 08960 Sant Just Desvern Spain
  • EURENCO Bofors AB, Kontorsvägen 6 SE-691 86 Karlskoga Sweden
  • EVAL Europe, Haven 1053 Nieuwe Weg 1 B2070 Zwijndrecht Antwerp Belgium
  • Evonik Antwerpen NV, Tijsmanstunnel West 2040 Antwerpen 4 Flanders Belgium
  • FUJIFILM Electronic Materials (Europe) N.V., Keetberglaan 1A Haven 1061 2070 Zwijndrecht Antwerp Belgium
  • Gantrade Europe Limited, Birch House Fairfield Avenue TW18 4AB Staines Upon Thames Middlesex United Kingdom
  • GE Healthcare AS, Nycoveien 1 Postboks 4220 Nydalen 0401 Oslo Oslo Norway
  • Giovanni Bozzetto SpA, Via Provinciale, 12 24040 Filago Lombardia Italy
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden
  • Godavari Biorefineries B.V, Hoofdweg 640, 2C-5, 2nd Floor, 2132 MK - Hoofddorp 2132 MK Hoofddorp Netherlands
  • GOVI PRODUCTION COMPANY, Landegemstraat 8 9031 Drongen Belgium
  • Halliburton Manufacturing and Services Ltd, Halliburton House Howe Moss Crescent, Kirkhill Industrial Estate AB21 0JN Dyce Aberdeen United Kingdom
  • Helm AG, Nordkanalstraße 28 20097 Hamburg Germany
  • HML Europe BV, De Haal 82 1511 AT Oostzaan Netherlands
  • Huntsman Textile Effects (Germany) GmbH, Rehlinger Str. 1 D-86462 Langweid a.Lech Germany
  • IFF Benicarlo, S.L., Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain
  • IGM Resins Italia S.r.l, Via Vincenzo Monti, 8 20123 Milano Italy
  • INDORAMA VENTURES QUÍMICA S.L.U., Polígono Industrial Guadarranque, 0, sin número 11360 San Roque Cádiz Spain
  • INEOS nv, Haven 1053 -- Nieuwe Weg 1 2070 Zwijndrecht Belgium
  • International Flavours & Fragrances I.F.F. (Great Britain) Ltd., Duddery Hill CB9 8LG Haverhill United Kingdom
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • J.R. SABATER, S.A., Avenida de Murcia 61 30110 MURCIA Spain
  • Jubilant Lifesciences NV, Axxes Business Park - Guldensporenpark 22 - block C 9820 Merelbeke Belgium
  • Jungbunzlauer Ladenburg GmbH, Dr. Albert-Reimann-Strasse 18 68526 Ladenburg Germany
  • Justesa Imagen S.A.U., Avenida de San Pablo 27 28823 Coslada Madrid Spain
  • KCC Europe GmbH, Hansaring 61 50670 Köln Germany
  • Kemira Oyj, Energiakatu 4 P.O.Box 330 FI-00101 HELSINKI Finland
  • Kerry (NL) B.V., Lindtsedijk 8 3336 LE Zwijndrecht Netherlands Netherlands
  • KIST Europe Forschungsgesellschaft mbH_18, Universitaet des Saarlandes Campus E 71 D-66123 Saarbruecken Germany
  • Kraton Chemical AB OR1, Massvagen 15 P.O. Box 66 SE-820 22 Sandarne Sweden
  • Kuhne Polska Sp. z o.o., Orkana 65 58-307 Wałbrzych Dolny Śląsk Poland
  • Kuraray Europe GmbH, Philipp-Reis-Str. 4 65795 Hattersheim Germany
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • Lasenor Emul, Ctra C55 Km5.3 08640 Olesa de Montserrat Barcelona Spain
  • Lawter BVBA, Haven 1520 Ketenislaan 1 B-9130 Kallo East Flanders Belgium
  • Lenzing AG, Werkstraße 4860 Lenzing Austria
  • LES DERIVES RESINIQUES ET TERPENIQUES, 30 rue Gambetta B.P. 206 40105 Dax Cedex France
  • Lifosa-2, Juodkiskio 50 LT-57502 Kedainiai Lithuania
  • Lubrizol France SAS, 25 Quai de France 76100 ROUEN France
  • Lyondell Chemie Nederland B.V., Deltseplein 27E 3013 AA Rotterdam Netherlands
  • MC-Bauchemie Müller GmbH & Co. KG, Am Kruppwald 1-8 46238 Bottrop Germany
  • Merck KGaA, Frankfurter Strasse 250 64293 Darmstadt Germany
  • Merck Santé s.a.s., 37, rue Saint Romain TSA 40123 69379 LYON CEDEX France
  • MHM Holding GmbH, Feldkirchener Straße 15 D-85551 Kirchheim Germany
  • Miki Europe GmbH, Immermannstr. 35 40210 Düsseldorf Germany
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • Nalco Limited, P.O. Box 11, Winnington Avenue, CW8 4DX Northwich, Cheshire United Kingdom
  • Naturamole, ZA du Villaret 38350 Susville France
  • Nitrochemie Aschau GmbH, Liebigstrasse 17 84544 Aschau am Inn Germany
  • Nouryon Industrial Chemicals B.V., Velperweg 76 6824 BM Arnhem Netherlands
  • NOVACYL SAS, 21 chemin de la Sauvegarde « 21 Ecully Parc » - CS 33167 69134 ECULLY CEDEX France
  • OKL a.s., U Bzinku 409 696 81 Bzenec Czech Republic
  • OQ Chemicals GmbH, Rheinpromenade 4a 40789 Monheim NRW Germany
  • OQEMA GmbH, Aachener Str. 258 41061 Moenchengladbach Germany
  • OSTCHEM Germany GmbH Sev, Erdmannstr. 10 22765 Hamburg Germany
  • Oxyde Belgium, Gloriantlaan 38 2050 Antwerp Belgium
  • Petrochemical Commercial Company (UK) Ltd, 24, GROSVENOR GARDENS SW1W 0DH LONDON EUROPE United Kingdom
  • PRODASYNTH, PI DES BOIS DE GRASSE 4 AV. JOSEPH HONORE ISNARD 06130 GRASSE France
  • proFagus GmbH, Uslarer Str. 30 37194 Bodenfelde Germany
  • Pulcra Chemicals S.L., Polígono Industrial San Vicente 08755 Castellbisbal (Barcelona) Spain
  • Puratos NV, Industrialaan 25 - Zone Maalbeek 1702 Groot-Bijgaarden Belgium
  • Reach & Colours s.r.o, Thunovská 196/19 Malá Strana 118 00 Prague Czech Republic
  • Reach & Colours Trade Kft, Levente u. 14/a 2161 Csomád Hungary
  • REACH&Colours Kft, Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • Robertet, 37 Avenue Sidi Brahim 06130 Grasse France
  • Roche Diagnostics GmbH, Sandhoferstrasse 116 68305 Mannheim Germany
  • Rotam Crop Protection Europe SAS, 75 cours Albert Thomas-6e avenue/Batiment D 69003 Lyon France
  • RSI ChemRep Europe Ltd (D001), 27-30 Merchants Quay Merchants House 8 Dublin Ireland
  • S.A. ROBAMA, Ctra NII km 680 PI Mas Puigvert 08389 PALAFOLLS Barcelona Spain
  • SABIC Petrochemicals B.V., Europaboulevard 1 6135 LD Sittard Netherlands
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • SCC GmbH, Am Grenzgraben 11 55545 Bad Kreuznach Germany
  • SEKAB Biofuels & Chemicals, Box286 89126 Örnsköldsvik Sweden
  • Siegfried PharmaChemikalien Minden GmbH, Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany
  • Sigma-Aldrich Biochemie GmbH, Georg-Heyken-Str. 14 21147 Hamburg Germany
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SIGMA-ALDRICH CHIMIE SARL, 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France
  • Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom
  • Sigma-Aldrich Ireland Ltd, Vale Road . Arklow Co. Wicklow Ireland
  • Sigma-Aldrich Sweden AB, Solkraftsvägen 14C S-135 70 Stockholm Sweden
  • Solenis Netherlands B.V., Fascinatio Boulevard 522 2909 VA CAPELLE A/D IJSSEL Netherlands
  • Specialty Electronic Materials Netherlands BV, Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • STERIS Ireland Limited, IDA Business and Technology Park Country Offialy R35 X865 Tullamore Ireland
  • Titan Wood BV, IPKW Westervoortsedijk 73 6827 AV Arnhem Netherlands
  • Tricoya Ventures UK Limited, Brettenham House 19 Lancaster Place WC2E7EN London United Kingdom
  • TÜV SÜD Iberia S.A.U. (056), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • UMCO GmbH, Georg-Wilhelm-Straße 187 21107 Hamburg Germany
  • Univar Solutions B.V., Schouwburgplein 30-34 NL-3012 CL Rotterdam Netherlands
  • Vinaigrerie Fuchs SA, 1-3 Zac Des Bregaudieres 17390 La Tremblade France
  • Vinaigrerie St. Martinus S.A., Ramerstraat 26 B1760 Roosdaal Belgium
  • VWR International BVBA, Haasrode Researchpark 2020 3001 Leuven Belgium
  • Wacker Chemie AG, Hanns-Seidel-Platz 4 81737 Muenchen Germany
  • Wacker Chemie AG (OR_WCC), Johannes-Hess-Strasse 24 84489 Burghausen Germany
  • Warwick International Group Ltd, Mostyn CH8 9HE Holywell Flintshire United Kingdom
  • WeylChem Höchst GmbH, Brüningstr. 50 D-65929 Frankfurt am Main Germany
  • WeylChem Wiesbaden GmbH, Industriepark Kalle-Albert Kasteler Str. 45 65203 Wiesbaden Germany
  • Yorkshire Farben GmbH, Mevissenstrasse 72 D-47803 Krefeld Germany
  • Avantor Performance Materials Poland S.A., Sowińskiego 11 44-100 Gliwice Poland
  • Celanese Chemicals Ibérica, S.L., Carretera Nacional 340, Km. 1155 Polígono Industrial TAQSA E-43.206 Reus (Tarragona) Spain
  • Eastman Chemical Workington Limited, Siddick CA14 1LG Workington Cumbria United Kingdom
  • Honeywell Specialty Chemicals Seelze GmbH, Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany
  • IDC International Detergent Chemicals Limited, Little Island, Co.Cork Cork Cork Ireland
  • Intertek Deutschland GmbH CWCL, Stangenstr.1 70771 Leinfelden-Echterdingen Germany
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • NOVICHEM Sp z o.o., Główna 4 41-508 PL Chorzów Poland
  • Solvay Solutions UK Limited, 34 CLARENDON ROAD WD17 1JJ WATFORD Hertfordshire United Kingdom

Substance names and other identifiers

acetic acid ... %
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
ACETIC ACID SOLUTION, more than 10% and less than 50% acid, by mass
Inland Transport of Dangerous Goods Directive, Annex III - AND, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
ACETIC ACID SOLUTION, not less than 50% but not more than 80% acid, by mass
Inland Transport of Dangerous Goods Directive, Annex III - AND, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
acetic acid … %
C&L Inventory
Acetic acid, glacial
Other
ACETIC ACID, GLACIAL or ACETIC ACID SOLUTION, more than 80% acid, by mass
Inland Transport of Dangerous Goods Directive, Annex III - AND, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
...% acto rūgštis (lt)
C&L Inventory
200–580–7 (it)
Biocidal active substances
Acetic acid (no)
Biocidal active substances
Acid acetic (ro)
Biocidal active substances
acid acetic…% (ro)
C&L Inventory
Acide acétique (fr)
Biocidal active substances
acide acétique à …% (fr)
C&L Inventory
acido acetico ... % (it)
C&L Inventory
Acto rūgštis (lt)
Biocidal active substances
Azijnzuur (nl)
Biocidal active substances
azijnzuur ... % (nl)
C&L Inventory
Aċidu aċetiku (mt)
Biocidal active substances
Ecetsav (hu)
Biocidal active substances
ecetsav …% (hu)
C&L Inventory
Eddikesyre (da)
Biocidal active substances
eddikesyre ... % (da)
C&L Inventory
eddiksyre ... % (no)
C&L Inventory
Essigsäure (de)
Biocidal active substances
Essigsäure ... % (de)
C&L Inventory
Etaanhape (äädikhape) …% (et)
C&L Inventory
Etikkahappo (fi)
Biocidal active substances
Etikkahappo... % (fi)
C&L Inventory
Etiķskābe (lv)
Biocidal active substances
Kwas octowy (pl)
Biocidal active substances
kwas octowy ... % (pl)
C&L Inventory
Kyselina octová (cs)
Biocidal active substances
kyselina octová ... % (sk)
C&L Inventory
Ocetna kislina (sl)
Biocidal active substances
ocetna kislina...% (sl)
C&L Inventory
Octena kiselina (hr)
Biocidal active substances
octena kiselina ... % (hr)
C&L Inventory
octová kyselina ...% (cs)
C&L Inventory
Ácido acético (es)
Biocidal active substances
ácido acético ... % (es)
C&L Inventory
Ättiksyra (sv)
Biocidal active substances
ättiksyra ... % (sv)
C&L Inventory
Äädikhape (et)
Biocidal active substances
Οξικό οξύ (el)
Biocidal active substances
οξικό οξύ ... % (el)
C&L Inventory
Оцетна киселина (bg)
Biocidal active substances
оцетна киселина.. % (bg)
C&L Inventory
…% etiķskābe (lv)
C&L Inventory
acetic
C&L Inventory
Acetic acid (synthetic)
Registration dossier
acetic acid 100 %
C&L Inventory
acetic acid 60%
C&L Inventory
Acetic Acid 80%
C&L Inventory
acetic acid 99 %
C&L Inventory
acetic acid 99,8%
C&L Inventory
Acetic Acid [for General Organic Chemistry]
C&L Inventory
ACETIC ACID GLACIAL
C&L Inventory, Registration dossier
acetic acid …%
C&L Inventory
Acetic acid, ethanoic acid
Registration dossier
Acetic acid, Ethanoic acid,Glacial acetic acid
Registration dossier
acetic acid, of a concentration of more than 10 per cent, by weight, of acetic acid
C&L Inventory
acetic acid...%
C&L Inventory
Acetid acid
C&L Inventory, Registration dossier
ACIDE ACETIQUE
C&L Inventory
Acide ethanoique
C&L Inventory
acido acetico
C&L Inventory
actic acid
C&L Inventory
Ethanoic Acid
C&L Inventory, Registration dossier
Ethanoic acid,Glacial acetic acid
Registration dossier
etic acid … %
C&L Inventory
Glacial acetic acid, Ethanoic acid
Registration dossier
not available
C&L Inventory
octová kyselina
C&L Inventory
Reaction mass of water and 9-(2-carboxyphenyl)-3,6-bis(diethylamino)xanthylium acetate
C&L Inventory
ácido etanoico
C&L Inventory
A-UT6581(K1)PTA
Registration dossier
Acetic acid (7CI, 8CI, 9CI)
Registration dossier
Acetic acid, 100%
Registration dossier
Aci-Jel
Registration dossier
Acide acétique dilué
Registration dossier
Albrite Acetic Acid 80%
Registration dossier
CHINT: Acetic acid
Registration dossier
Dilute acetic acid
Registration dossier
ECO2200-A-BLACK(T)
Registration dossier
ECO2200-B
Registration dossier
ED2800-A-BLACK(E)
Registration dossier
Essigsaeure
Registration dossier
Ethanoic acid monomer
Registration dossier
Ethylic acid
Registration dossier
Glacial acetic acid
Registration dossier
GLACIAL ACETIC ACID GMP
C&L Inventory
Ijs azijnzuur
Registration dossier
Industrial acetic acid
Registration dossier
Lenzing Acetic acid 100%
Registration dossier
methane carboxylic acid
Registration dossier
Methanecarboxylic acid
Registration dossier
No trade names are assigned to this substance
Registration dossier
Phase I REACH Kandidat
Registration dossier
SI6020Z
Registration dossier
SI6037Z
Registration dossier
SI6050Z
Registration dossier
SI6070Z
Registration dossier
SI6350Z
Registration dossier
Spirit vinegar
Registration dossier
Technical acetic acid
Registration dossier
UT6581(K1)PTA-1000
Registration dossier
UT6581(K1)PTA-1999
Registration dossier
UT6581(K1)PTB
Registration dossier
UT6581-A-10GY6.5/3
Registration dossier
UT6581-A-N.1.5
Registration dossier
UT6581-A-RAL9006(H)
Registration dossier
UT6581-B
Registration dossier
Vinegar acid
Registration dossier
1053656-97-5
CAS number
Other
607-002-00-6
Index number
C&L Inventory
64-19-7
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Inland Transport of Dangerous Goods Directive, Annex III - AND, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, Occupational Exposure Limits - 4th list - Indicative OELVs, Annexes II, III, IV, VII - Defined & Temporary Maximum Residue Levels, EU. Annex of Approved Active Substances for Plant Protection Products, FCM and Articles Regulation, Annex I - Authorised Substances, Food Contact Regenerated Cellulose Directive - Authorised Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
77671-22-8
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Not specified (100%) [1]
C Odour
Pungent (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 1 study processed
R Melting / freezing point
16.64 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
16.49 °C

Boiling point

Study results
  • 2 studies submitted
  • 1 study processed
R Boiling point
117.9 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
117.75 °C

Density

Study results
  • 2 studies submitted
  • 1 study processed
R Density
1.04 g/cm³ @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 2 studies submitted
  • 1 study processed
R Vapour pressure
20.79 hPa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
20.79 hPa @ 24.85 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
-0.17 @ 25 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-0.17 @ 20 °C

Water solubility

Study results
  • 2 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
602.9 g/L @ 25 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
602.9 g/L @ 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 2 studies submitted
  • 1 study processed
R Flash point
39 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
38.85 °C

Auto flammability

Study results
  • 2 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
463 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
462.85 °C

Flammability

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 2 studies submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
4.76 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
1.056 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 1 study processed
R Dissipation half life (DT50)
26.7 days [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 4 studies submitted
  • 3 studies processed
C Interpretation of results
Readily biodegradable (100%) [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3 1
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
3.16

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
1.153

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
0.21 Pa m³/mol @ 25 °C and 101.33 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0.21 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 4 summaries submitted
  • 4 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 3.058 mg/L (4)
Intermittent releases (freshwater) 30.58 mg/L (4)
Marine water 305.8 µg/L (4)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 85 mg/L (4)
Sediment (freshwater) 11.36 mg/kg sediment dw (4)
Sediment (marine water) 1.136 mg/kg sediment dw (4)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 470 µg/kg soil dw (4)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 300.82 - 1 000 mg/L [2]
NOEC (4 days) 300.82 - 1 000 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 4 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
300.82 mg/L
LC50 for marine water fish
300.82 mg/L

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
EC50 (48 h) 300.82 - 1 000 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
300.82 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 300.82 - 1 000 mg/L [2]
NOEC (72 h) 300.82 - 1 000 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for marine water algae
300.82 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 4 summaries submitted
  • 4 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (No hazard identified) -
Acute /short term: (No hazard identified) -
Local Effects
Long-term: (DNEL) 25 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 25 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: Medium hazard (no threshold derived)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 25 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 25 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: Medium hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
Medium hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 100 %
Inhalation: 100 %

Acute toxicity

Study results
oral
  • 3 studies submitted
  • 2 studies processed
P/RResults
LD50 3 310 mg/kg bw (rat) [1]
LD50 4 960 mg/kg bw (mouse) [1]

Type of Study provided
oral
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
inhalation
  • 5 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 8.5 - 12.7 mg/L air (rat) [3]
M/CInterpretations of results
Harmful [1]

inhalation
Studies with data
Key study
Supporting study
Weight of evidence 5
Other
Data waiving
no waivers
dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 3 310 mg/kg bw
Inhalation route:
Adverse effect observed LC50 40 000 mg/m³

Irritation / corrosion

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 3 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 290 mg/kg bw/day [1]
NOAEL (pig): 450 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
Study data: inhalation
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 345 mg/kg bw/day (subacute, mouse)

Neurotoxicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant