Registration Dossier
Registration Dossier
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EC number: 431-060-1 | CAS number: 153719-38-1
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of CA 2343A to activated sludge was determined in a 3-hours respiration inhibition test, according to GLP Guideline OECD 209, under aerobic conditions at room temperature (20 +/-2 ºC).
The test substance concentrations tested were 100, 32, 10, 3.2 and 1.0 mg/l. The reference substance 3,5-Dichlorophenol was tested in concentrations of 32, 10 and 3.2 mg/l.
The test system consisted of activated sludge collected from a communal sewage treatment plant. 1.59 g/l sludge (dry weight) was used in a test volume of 100 ml.
The respiration rate of the activated sludge fed with a standard amount of nutrient solution was measured after a contact time of 3 hours with the test substance. The reference substance 3,5-Dichlorophenol and a blank (nutrient solution, inoculum and water) served as controls. An EC50 (3h) value for CA 2343A of > 100 mg/l was calculated.
Based on the result, EC50 (3h) > 100 mg/l, CA 2343A is "not toxic to bacteria".
Key value for chemical safety assessment
Additional information
Guideline Test Type |
Species |
EC50(3h) |
Reference |
Reliability |
OECD 209 |
activated sludge |
> 100 mg/l |
Grade, R., Ciba-Geigy Ltd., 1996 |
Reliable without restriction |
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