Registration Dossier
Registration Dossier
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EC number: 405-820-6 | CAS number: 30025-38-8
Endpoint summary
Administrative data
Description of key information
Two guideline tests to evaluate either dermal irritancy or ocular irritancy of DPGEE in the rabbit were negative by accepted EU criteria.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Justification for classification or non-classification
SKIN: The level of response of all end points was insufficient to trigger classification under directive 67/548 or regulation 1272/2008.
EYE: The level of response of all end points was insufficient to trigger classification under directive 67/548 or regulation 1272/2008. Details shown below:
Mean of measurements at 24, 48, 72 hours
|
Animal 1 |
Animal 2 |
Animal 3 |
Classification under 67/548 |
Classification under 1272/2008 |
Corneal effects |
1 |
0.3 |
0.3 |
No |
No |
Iritis |
0 |
0 |
0 |
No |
No |
Conjunctival effects |
1.7 |
1.7 |
1.0 |
No |
No |
Chemosis |
1.0 |
0.7 |
0.3 |
No |
No |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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