Registration Dossier

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study - original study report available

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1990
Report Date:
1990

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
other: ISO standard 1388/6-1981
Deviations:
no
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
Deviations:
not specified
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Ethoxy propoxy propanol
- Substance type: Glycol ether
- Physical state: Colourless liquid
- Lot/batch No.: HD 160/90-787

Results and discussion

Solubility in organic solvents / fat solubility
Medium:
other: "standard liquid fat" (oil)
Solubility:
0.01 - 100 other: ml per ml fat
Temp.:
37 °C
Test substance stable:
not determined
Details on results:
miscible range 0.01 to 100ml/ml fat. pH remained at 6.

Applicant's summary and conclusion

Conclusions:
Completely miscible in range 0.001 to 100 ml of test substance per ml fat.
Executive summary:

Ethoxy propoxy propanol is completely miscible in fat over a wider range of proportions.