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EC number: 200-372-6 | CAS number: 58-27-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experimental starting date: 07 November 2017. Experimental completion date: 10 November 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
Test material
- Reference substance name:
- Menadione
- EC Number:
- 200-372-6
- EC Name:
- Menadione
- Cas Number:
- 58-27-5
- Molecular formula:
- C11H8O2
- IUPAC Name:
- 2-methyl-1,4-dihydronaphthalene-1,4-dione
Constituent 1
- Specific details on test material used for the study:
- Identification: Beta-Menadione
CAS No: 58-27-5
Appearance/Physical state: Yellow powder
Batch: J17022301
Purity: 99.4%
Expiry date: 22 February 2018
Storage conditions: Room temperature in the dark
Results and discussion
Vapour pressure
- Temp.:
- 25 °C
- Vapour pressure:
- 0.07 Pa
Any other information on results incl. tables
Results
Run 6
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 6 gives the following statistical data using an unweighted least squares treatment. Slope: -4.50 x 10^3
Standard error in slope: 66.5
Intercept: 13.9
Standard error in intercept: 0.219
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp (Pa)) = -4.50 x 10^3 /temp(K) + 13.9 The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -1.16.
Run 7
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 7 gives the following statistical data using an unweighted least squares treatment. Slope: -4.49 x 10^3
Standard error in slope: 85.2
Intercept: 13.9
Standard error in intercept: 0.281
The results obtained indicate the following vapor pressure relationship: Log10 (Vp (Pa)) = -4.49 x 10^3 /temp(K) + 13.9 The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -1.16.
Run 8
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 8 gives the following statistical data using an unweighted least squares treatment. Slope: -4.39 x 10^3
Standard error in slope: 88.5
Intercept: 13.6
Standard error in intercept: 0.292
The results obtained indicate the following vapor pressure relationship: Log10 (Vp (Pa)) = -4.39 x 10^3 /temp(K) + 13.6 The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -1.16.
Summary of Results
The values of vapor pressure at 25 °C extrapolated from each graph are summarized in the following table:
Run | Log10 [Vp(25 ºC)] |
6 | -1.16 |
7 | -1.16 |
8 | -1.16 |
Mean | -1.16 |
Vapor Pressure | 6.95 x 10^-2 Pa |
Discussion
The test item did not change in appearance under the conditions used in the determination.
The results may represent rounded values obtained by calculations based on the exact raw data
A total of 8 runs were completed for the main sequence. Equilibrium with regards to vapor pressure was assessed to have been reached over the final 3 runs. Thus the final 3 runs have been used to calculate the definitive vapor pressure value for the test item.
Applicant's summary and conclusion
- Conclusions:
- The vapor pressure of the test item has been determined to be 7.0 x 10^-2 Pa at 25 ºC.
- Executive summary:
The vapor pressure of Beta-Menadione has been determined to be 7.0 x 10^-2 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.
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