Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 23-02-2018 to 25-07-2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
other: ISO 11357-1. (2009). Plastics -- Differential Scanning Calorimetry (DSC) – Part 1: General principles. CEN, Bruxelles
Deviations:
no
Qualifier:
according to
Guideline:
other: ISO 11357-3. (2013). Plastics -- Differential Scanning Calorimetry (DSC) – Part 3: Determination of temperature and enthalpy of melting and crystallization. CEN, Bruxelles
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
< -20 °C
Atm. press.:
968 hPa
Decomposition:
no
Remarks on result:
other: Mean of 2 determinations

Any other information on results incl. tables

Results of this study are considered valid as the following criteria were met:

-       The crucible was visually checked and no degradation was observed during the study. By opening it, it appeared that there was no test item left in the crucible.

-       The temperature difference obtained between the two determinations is less than 0.5°C up to 326.85°C and less than 2°C up to 1000°C.

-       The melting point obtained on the reference substance, Indium, is included in the checking chart limits.

-       The corrected sensitivity, i.e. the enthalpy measured during the melting of indium, does not differ by more than 10% from the expected value.

Applicant's summary and conclusion

Conclusions:
The melting point of the substance was determined as <– 20 °C.
Executive summary:

A study was performed to determine the melting point of the test item. The method used was Differential Scanning Calorimetry (DSC) and the test was according to Regulation EC No. 440/2008 Method A.1 and OECD Test Guideline 102 , "Melting Point/Melting Range" and following GLP. In this method, two crucibles were put in the apparatus furnace under inert atmosphere (helium) at atmospheric pressure. One crucible contained the test item, the other was empty and considered as the reference. A specific temperature program was applied. The crucibles were linked to two thermocouples fixed on the TG-DSC sample carrier. Heat flow differences between the two crucibles and mass variation were recorded on a thermogram. A cooling system using liquid nitrogen allowed experiments with low temperatures down to -120°C. Two trials were conducted and corresponding thermograms were obtained, giving the following results:

Trial 1: <-20°C at 968 hPa; Trial 2: <-20°C at 968 hPa.

The melting point values respect validity criteria. Moreover, the melting point of the Indium respects the checking cards limits (156.5°C for a reference value of 156.6°C) so as its enthalpy (30.96 J/g for a reference value of 28.6 J/g).

The melting point of the substance was determined as < – 20.0 °C.