Registration Dossier

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 23-02-2018 to 25-07-2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling Point/Boiling Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
other: ISO 11357-1. (2009). Plastics -- Differential Scanning Calorimetry (DSC) – Part 1: General pr inciples. CEN, Bruxelles
Deviations:
no
Qualifier:
according to
Guideline:
other: ISO 11357-3. (2013). Plastics -- Differential Scanning Calorimetry (DSC) – Part 3: Determinat ion of temperature and enthalpy of melting and crystallization. CEN, Bruxelles
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Boiling point
Key result
Boiling pt.:
304.2 °C
Atm. press.:
101.3 kPa
Decomposition:
no
Remarks on result:
other: mean of 304.1 °C for the first determination and 304.3 °C for the second determination

Any other information on results incl. tables

Results of this study are considered valid as the following criteria were met:

-       The crucible was visually checked and no degradation was observed during the study. By opening it, it appeared that there was no test item left in the crucible.

-       The temperature difference obtained between the two determinations is less than 0.5°C up to 326.85°C and less than 2°C up to 1000°C.

The initial boiling point of the test item has been determined to be 301.9 °C at 968.0 hPa for the first determination and 302.1 °C at 968.0 hPa for the second determination.

In case of small pressure deviations the boiling temperature at standard pressure can be calculated following the equation of Sidney-Young. The corrected values following Sidney-Young equation has been determined to be 304.2 °C at 101.3 kPa (mean of 304.1 °C for the first determination and 304.3 °C for the second determination).

Applicant's summary and conclusion

Conclusions:
The corrected values following Sidney-Young equation has been determined to be 304.2 °C at 101.3 kPa (mean of 304.1 °C for the first determination and 304.3 °C for the second determination).
Executive summary:

A study was performed to determine the melting point of the test item. The method used was Differential Scanning Calorimetry (DSC) and the test was according to Regulation EC No. 440/2008 Method A.2 and OECD Test Guideline 103 , "Boiling Point/Boiling Range" and following GLP. In this method, two crucibles were put in the apparatus furnace under inert atmosphere (helium) at atmospheric pressure. One crucible contained the test item, the other was empty and considered as the reference. A specific temperature program was applied. The crucibles were linked to two thermocouples fixed on the TGDSC sample carrier. Heat flow differences between the two crucibles and mass variation were recorded

on a thermogram. A cooling system using liquid nitrogen allowed experiments with low temperatures down to -120°C. Two trials were conducted and corresponding thermograms were obtained, giving the following results:

Trial 1: 301.9°C at 968 hPa; Trial 2: 302.1°C at 968 hPa (Initial boiling point without Sydney-Young correction).

The corrected values following Sidney-Young equation has been determined to be 304.2 °C at 101.3 kPa (mean of 304.1 °C for the first determination and 304.3 °C for the second determination).