Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09 February - 02 June 2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP, Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report Date:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
GLP compliance:
yes (incl. certificate)
Remarks:
The Department of Health of the Government of the United Kingdom
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Benzene, 1,1 ‘-(1 ‚2-ethanediyl)bis-, brominated, [CAS No. 109283440-6]
- Substance type: white powder
- Physical state: solid
- Analytical purity: no data
- Lot/batch No.: 20090105
- Storage condition of test material: room temperature in the dark

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
> 6.5

Any other information on results incl. tables

Mean 1og10 Pow: >6.5

Partition coefficient: >3.16 x 106

Applicant's summary and conclusion

Conclusions:
The partition coefficient of the test material has been determined to be greater than 3.16 x 10^6, log10 Pow>6.5.