Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 500-214-9 | CAS number: 68440-06-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
No effects up to the water solubility limit.
Key value for chemical safety assessment
Additional information
Since no studies investigating the toxicity of Fatty acids, C18-unsatd., dimers, hydrogenated, 2-ethylhexyl esters (CAS 68440-06-2) to aquatic algae are available, in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5 a read-across to the structurally related source substance Fatty acids, C18-unsatd., dimers, 2-ethylhexyl esters (CAS 68334-05-4) was conducted.The target substance Fatty acids, C18-unsatd., dimers, hydrogenated, 2-ethylhexyl esters (CAS 68440-06-2) is characterized by two dimerised fatty acid moieties (C18) esterified with the alcohol component 2-ethylhexanol. The source substance Fatty acids, C18-unsatd., dimers, 2-ethylhexyl esters (CAS 68334-05-4) is characterized as a dimerised ester of two C18:1 fatty acids esterified with 2-ethylhexanol.This read-across is justified in detail in the overall summary (IUCLID Section 6.1) and within the analogue justification in IUCLID Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was used for the assessment.
The study with the read-across substance Fatty acids, C18-unsatd., dimers, 2-ethylhexyl esters (CAS 68334-05-4) was performed according to OECD 201 (GLP) and investigated the toxicity to freshwater algae (Swarbrick and Smyth, 2005). The green algae Selenastrum capricornutum was exposed for 72 h to a limit Water Accommodated Fraction (WAF) concentration of nominal 100 mg/L. No effects on algal growth was observed resulting in an EL50 (72 h) > 100 mg/L (nominal) The NOELR (72 h) was derived to be ≥ 100 mg/L (nominal).
Based on the available results from a structurally related read-across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) which is characterized by a similar ecotoxicological profile and comparable structure, it can be concluded that Fatty acids, C18-unsatd., dimers, 2-ethylhexyl esters (CAS 68334-05-4) will not exhibit effects on aquatic algae up to the limit of water solubility.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
