Registration Dossier
Registration Dossier
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EC number: 204-289-6 | CAS number: 118-96-7
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- according to guideline
- Guideline:
- other: Toxicity experiments were conducted following U.S. Environmental Protection Agency guidance 1994. Methods for measuring the toxicity of sediment-associated contaminants with estuarine and marine amphipods. EPA 600/R-94/025. Narragansett, RI
- GLP compliance:
- not specified
- Test organisms (species):
- other: amphipod: Eohaustorius estuarius
- Water media type:
- saltwater
- Total exposure duration:
- 10 d
- Duration:
- 10 d
- Dose descriptor:
- LC50
- Effect conc.:
- 36 other: mg/kg dw
- Remarks on result:
- other: 95% CI; YB sediment
- Duration:
- 10 d
- Dose descriptor:
- LC50
- Effect conc.:
- 23 other: mg/kg dw
- Remarks on result:
- other: 95% CI, SDB sediment
- Duration:
- 10 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 24 other: mg/kg dw
- Remarks on result:
- other: 95% CI, YB sediment
- Duration:
- 10 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 20 other: mg/kg dw
- Remarks on result:
- other: 95% CI; SDB sediment
- Duration:
- 10 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 44 other: mg/kg dw
- Remarks on result:
- other: 95% CI; YB sediment
- Duration:
- 10 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 38 other: mg/kg dw
- Remarks on result:
- other: 95% CI; SDB sediment
- Executive summary:
Lowest NOEC value is 20 mg/kg, whereas density is 1.64 kg/m3 (0.00164 kg/L)
NOEC 20 mg/kg = 0.0328 mg/L
Reference
Description of key information
NOEC for marine water invertabrates has been recalculated from NOEC mg/kg based on substance density (publication nr 25).
Lowest NOEC value is 20 mg/kg, whereas density is 1.64 kg/m3 (0.00164 kg/L)
NOEC 20 mg/kg = 0.0328 mg/L
Key value for chemical safety assessment
Marine water invertebrates
Marine water invertebrates
- Dose descriptor:
- NOEC
- Effect concentration:
- 0.033 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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