Registration Dossier
Registration Dossier
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EC number: 227-824-5 | CAS number: 5994-61-6
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- Not reported
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment.
- Justification for data waiving:
- other:
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 986
- Report date:
- 1986
Materials and methods
- Principles of method if other than guideline:
- Test material was administered dermally to albino rabbits for the determination of acute dermal toxicity.
- GLP compliance:
- not specified
- Test type:
- other: Not reported
- Limit test:
- no
Test material
- Reference substance name:
- N-(carboxymethyl)-N-(phosphonomethyl)glycine
- EC Number:
- 227-824-5
- EC Name:
- N-(carboxymethyl)-N-(phosphonomethyl)glycine
- Cas Number:
- 5994-61-6
- Molecular formula:
- C5H10NO7P
- IUPAC Name:
- 2-[(carboxymethyl)(phosphonomethyl)amino]acetic acid
- Details on test material:
- - Name of test material (as cited in study report): Glyphosate Intermediate
- Analytical purity: 98.05 %
- Lot/batch No.: 4-86-587
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- other: Albino (strain not specified)
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- other: Saline (0.9 %)
- Duration of exposure:
- 24 h
- Doses:
- Not reported
- No. of animals per sex per dose:
- Not reported
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
Any other information on results incl. tables
None
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: other: EU CLP
- Conclusions:
- Under the test conditions, the acute dermal LD50 of the test material for rat was > 5,000 mg/kg bw.
- Executive summary:
Under the test conditions, the acute dermal LD50 of the test material for rat was > 5,000 mg/kg bw.
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