1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione

pH

Administrative data

Endpoint:

pH

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20/2/2016 - 20/2/2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard OECD test guidelines

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2016

Report date:

2016

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: OECD 122

Principles of method if other than guideline:

The pH determination of test item was done as per the test guideline OECD 122. The pH of the test solution was determined with the help of digital pH meter.

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione

EC Number:

253-326-2

EC Name:

1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione

Cas Number:

37052-78-1

Molecular formula:

C8H8N2OS

IUPAC Name:

5-methoxy-1,3-dihydro-2H-benzimidazole-2-thione

Test material form:

solid: particulate/powder

Remarks:

migrated information: powder

Details on test material:

- Name of test material (as cited in study report): 1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione
- Molecular formula (if other than submission substance): C8H8N2OS
- Molecular weight (if other than submission substance): 180.23 g/mol
- Substance type: Organic
- Physical state: Solid
- Analytical purity: 99.0 %

Specific details on test material used for the study:

- Name of test material : 5-methoxy-1,3-dihydro-2H-benzimidazole-2-thione
- Molecular formula : C8H8N2OS
- Molecular weight : 180.2302 g/mol
- Smiles notation : COc1ccc2c(c1)nc([nH]2)S
- InChl : 1S/C8H8N2OS/c1-11-5-2-3-6-7(4-5)10-8(12)9-6/h2-4H,1H3,(H2,9,10,12)
- Substance type : Organic
- Physical state : Solid

Results and discussion

pH value

Key result

pH value:

5.79

Temp.:

31.6 °C

Concentration:

1 vol%

Remarks on result:

other: No other detail available

Any other information on results incl. tables

TEST RESULTS

Method Details		Observations	Remarks if, any
Guideline	OECD 122
Method	pH measurement interface Microlab FS-524 and pH probe
Principle of method	The pH of an aqueous solution or dispersion in water is determined with a pH measurement interface equipped with an appropriate electrode system.
Temperature of 1% w/v test solution	-
pH (RESULT)	-	5.79
Inference	1.   Acidic 2.   Basic 3.   Neutral	Acidic

 

Applicant's summary and conclusion

Conclusions:

The pH determination of test item was done following OECD guideline 122. pH of 1% w/v dispersion was measured with the help of digital pH meter and it was observed to be 5.79 at 31.6°C indicating that the substance is acidic in nature.

Executive summary:

The pH determination of test item was done following OECD guideline 122. pH of 1% w/v dispersion was measured with the help of digital pH meter and it was observed to be 5.79 at 31.6°C indicating that the substance is acidic in nature.