Registration Dossier

Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Study period:
20/2/2016 - 20/2/2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard OECD test guidelines

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report Date:
2016

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: OECD 122
Principles of method if other than guideline:
The pH determination of test item was done as per the test guideline OECD 122. The pH of the test solution was determined with the help of digital pH meter.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
- Name of test material (as cited in study report): 1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione
- Molecular formula (if other than submission substance): C8H8N2OS
- Molecular weight (if other than submission substance): 180.23 g/mol
- Substance type: Organic
- Physical state: Solid
- Analytical purity: 99.0 %
Specific details on test material used for the study:
- Name of test material : 5-methoxy-1,3-dihydro-2H-benzimidazole-2-thione
- Molecular formula : C8H8N2OS
- Molecular weight : 180.2302 g/mol
- Smiles notation : COc1ccc2c(c1)nc([nH]2)S
- InChl : 1S/C8H8N2OS/c1-11-5-2-3-6-7(4-5)10-8(12)9-6/h2-4H,1H3,(H2,9,10,12)
- Substance type : Organic
- Physical state : Solid

Results and discussion

pH value
Key result
pH value:
5.79
Temp.:
31.6 °C
Concentration:
1 vol%
Remarks on result:
other: No other detail available

Any other information on results incl. tables

TEST RESULTS

Method Details

Observations

Remarks if, any

Guideline

OECD 122

 

 

Method

 

pH measurement interface Microlab FS-524 and pH probe

 

Principle of method

The pH of an aqueous solution or dispersion in water is determined with a pH measurement interface equipped with an appropriate electrode system.

 

Temperature of 1% w/v test solution

-

 

pH (RESULT)

 

-

5.79

Inference

1.   Acidic

2.   Basic

3.   Neutral

 

Acidic

 

Applicant's summary and conclusion

Conclusions:
The pH determination of test item was done following OECD guideline 122. pH of 1% w/v dispersion was measured with the help of digital pH meter and it was observed to be 5.79 at 31.6°C indicating that the substance is acidic in nature.
Executive summary:

The pH determination of test item was done following OECD guideline 122. pH of 1% w/v dispersion was measured with the help of digital pH meter and it was observed to be 5.79 at 31.6°C indicating that the substance is acidic in nature.