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EC number: 235-101-0 | CAS number: 12068-53-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30 Mar - 2 May 2005
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, non-GLP, no analytical concentration control
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: The test item was dissolved directly in dilution water. 0.100 g of test item was weighed and added to each vessel. Dilution water was filled up to 1000 mL per test vessel.
- Controls: Control contained dilution water only. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Source: Landesanstalt für Umweltschutz Baden-Württemberg, Griesbachstr. 1, D-76185 Karlsruhe
- Age at study initiation: < 24 h
- Method of breeding: medium M4; breeding in the testing facility under standardised laboratory conditions; breeding was performed in glass beakers (50mL) under the same conditions as in the test
- Feeding during test
- Food type: alga Desmodesmus subspicatus
- Amount: 0.5 - 1.5 mL/50 mL M4, depending on age
- Frequency: daily
ACCLIMATION
- Acclimation conditions (same as test or not): yes
- Type and amount of food: alga Desmodesmus subspicatus
- Feeding frequency: daily - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Hardness:
- 2 mmol/L
- Test temperature:
- 20.0 - 20.5 °C
- pH:
- 7.95 - 8.01
- Dissolved oxygen:
- 8.51 - 8.66 mg/L
- Nominal and measured concentrations:
- nominal: 0 and 100 mg/L
- Details on test conditions:
- TEST SYSTEM
- Test vessel:
- Material, size, fill volume: glass beaker, 1000 mL, fill volume: 1000mL
- Aeration: none
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
- Biomass loading rate: 200 mL test solution per Daphnia
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: dilution water according to ISO 6341
- Alkalinity: 200 mg/L CaCO3
- Ca/Mg ratio: 4:1
- Conductivity: 0.646 µS/cm
- Culture medium different from test medium: no
- Intervals of water quality measurement: pH, dissolved oxygen and temperature determined at the start and at the end
OTHER TEST CONDITIONS
- Adjustment of pH: no adjustment pf pH
- Photoperiod: 16 h light: 8 h dark
EFFECT PARAMETERS MEASURED (with observation intervals if applicable): number of immobilised daphnids, including discoloration, anomalies after 24 and 48 hours
TEST CONCENTRATIONS
- Range finding study
- Test concentrations: up to 100 mg/L
- Results used to determine the conditions for the definitive study: no immobilisation occurred - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: only NOEC reported
- Details on results:
- - No immobilisation occurred during the study
- No visible abnormalities were observed in the control or treatment groups
- Validity criteria are fulfilled - Results with reference substance (positive control):
- - Results with reference substance valid? yes
- EC50: 24 h 1.53 mg/L and 48 h 1.28 mg/L
Reference
Description of key information
EC50 (48h) > 100 mg/L for Daphnia magna (OECD 202)
Key value for chemical safety assessment
Additional information
One study on the short-term toxicity of Zinc aluminium oxide to aquatic invertebrates is available. This key study was performed as a limit test according to OECD Guideline 202, in a static system, using Daphnia magna as test organism (2005).The test solutions were prepared by direct addition of the item in dilution water, and were not filtered. The daphnids were exposed to a loading of 100 mg/L during 48 hours. No mortalities were observed and a NOEC of 100 mg/L (nominal) is reported. The EC50 is thus > 100 mg/L (nominal). Analytical measurements of zinc or aluminium were not performed.
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