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EC number: 235-101-0 | CAS number: 12068-53-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 Sep 2011 - 05 Feb 2013
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: GLP-Guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Series on Testing and Assessment No. 29 (23-Jul-2001): Guidance document on transformation/dissolution of metals and metal compounds in aqueous media
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht, Kaiser-Friedrich-Straße 7, 55116 Mainz, Germany
- Type of method:
- flask method
- Remarks:
- according to OECD No. 29 for 28 days
- Water solubility:
- < 1 µg/L
- Temp.:
- 22 °C
- pH:
- 6
- Remarks on result:
- other: the concentration of Al at two loading rate (0.1 and 1 mg/L)
- Water solubility:
- < 1 µg/L
- Temp.:
- 22 °C
- pH:
- 6
- Remarks on result:
- other: the concentration of Zn at loading rate 0.1 mg/L
- Water solubility:
- 6.3 µg/L
- Temp.:
- 22 °C
- pH:
- 6
- Remarks on result:
- other: the concentration of Zn at loading rate 1 mg/L
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Comparable to guideline study with acceptable restrictions.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- not specified
- Type of method:
- flask method
- Water solubility:
- < 1 other: ppm
- Remarks on result:
- other: No information on pH and temperature.
Referenceopen allclose all
In a preliminary study, the transformation/dissolution of the test item in aqueous media at three different pH values (6.09; 7.07; 8.0, nominal), each in three flasks with one loading (100 mg/L) was tested and concentrations of Aluminium and Zinc were determined. The
highest concentration of Zinc was measured at pH 6 (370 μg/L Zn, mean). The highest concentration of Aluminium was at pH 8 (33 μg/L Al). After consultation with the sponsor, pH 6.0 was chosen for the main study based on the measured amount of Zinc.
The main study was performed with two different loading concentrations of the test item (0.1 and 1 mg/L) over a period of 28 days with samplings after 2 h, 6 h, 1 d, 2 d, 7 d, 14 d, 21 d and 28 d. Two flasks without addition of test item were tested in parallel as blanks.
In the period 2 h – 14 days, the Aluminium in all flasks could not be quantified, since the concentrations were below the LOQ of Aluminium (1 μg/L) and in the period 21 – 28 d was determined at the LOQ of Aluminium (1 μg/L) in the same flasks. Compared to the blank values, only a minimal amount dissolved Aluminium could be detected in same flasks (< 1 μg/L Al, LOQ). This result confirms the findings of the pre-test. Therefore, the concentration of Aluminium and the test item in flasks 3 – 8 was stated as:
< 1 μg/L Al at 20.0 – 23.3 °C
= < 1 μg/L * 10-6 kg/m3 (SI units)
The measured concentrations of Zinc on days 7, 14, 21 and 28 in flasks 6 – 8 (1 mg/L, nominal) were similar. Therefore, all values on days 7, 14, 21 and 28 were used in calculation of the arithmetic mean:
Concentration of Zinc on Days 7, 14, 21 and 28
Fl. |
Content |
Conc. on day 7 [µg/L] |
Conc. on day 14 [µg/L] |
Conc. on day 21 [µg/L] |
Conc. on day 28 [µg/L] |
4 |
0.1 mg/L |
< 1 |
< 1 |
< 1 |
< 1 |
5 |
0.1 mg/L |
< 1 |
< 1 |
< 1 |
< 1 |
6 |
1 mg/L |
6.8 |
9.6 |
6.7 |
8.4 |
7 |
1 mg/L |
4.7 |
4.6 |
3.4 |
4.2 |
8 |
1 mg/L |
7.7 |
7.3 |
5.8 |
7.2 |
Measured Concentration of Zinc, Mean (Flasks 6, 7, 8) [µg/L] |
6.3 |
||||
Standard deviation (Flasks 6, 7, 8) [µg/L] |
1.9 |
||||
Relative Standard Deviation (Flask 6, 7, 8) [%] |
29 % |
The concentration of Zinc for the nominal concentration 1 mg/L test item was calculated from the measured values in the flasks 6 – 8 and was 6.3 μg/L Zn. The relative standard deviation for the values in the flasks 6 – 8 was higher than 20 % (29 %). This was considered as uncritical as the measurements of Zinc in this range (< 10 μg/L Zn) are inexact (at the LOQ of Zn) and the risk of carryover for such elements as Zinc, Iron and others is high.
Variation in measured values in the blanks (flasks 1 – 2) during the whole test confirms the risk of carryover during sampling or sample preparation in the laboratory Indikator.
Temperature had no direct influence on the measured concentrations, as variations in temperature did not correlate with variations in measured concentration.
The concentration of Zinc in the flasks 6 – 8 for the nominal concentration 1 mg/L was stated as
6.3 μg/L Zn (arithmetic mean value of three individual vessels, 24 values)
For the nominal concentration 0.1 mg/L, the concentration of Zinc lay below the LOQ of Zinc (1 μg/L):
< 1 μg/L Zn (0.1 mg/L test item nominal, mean value of two individual vessels, 16 values)
At all sampling points, the pH value lay in the range 6.0 ± 0.2. The temperature during 28 days was between 20 - 23.3 °C.
Preliminary study
In the preliminary study, no dissolution was observed.
Main study
The following ICP results were submitted by the sponsor’s laboratory:
Element |
Flask 1 (ppm) |
Flask 2 (ppm) |
Al |
<1 |
<1 |
Zn |
<1 |
<1 |
In the tested samples the analysed elements were < 1ppm.
Solubility result
The test substance D-Prism is virtually insoluble in water; the measured solubility in water is below 1 ppm.
Description of key information
The solubility of the substance is stated as <1 ppm.
From transformation/dissolution test:
< 1 µg/L Al and Zn at nominal loading rate of 0.1 mg/L test item, at pH 6 and at 20 - 23.3 °C;
< 1 µg/L Al and 6.3 µg/L Zn at nominal loading rate of 1 mg/L test item, at pH 6 and at 20 - 23.3 °C.
Key value for chemical safety assessment
Additional information
The water solubility of the test substance was determined under flask conditions according to OECD guideline 105.
A transformation /dissolution test according to OECD SERIES ON TESTING AND ASSESSMENT No. 29 was performed. The measured concentration of aluminium and zinc are very low (< 10 µg/L).
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