Registration Dossier
Registration Dossier
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EC number: 256-367-4 | CAS number: 49553-76-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (14d) ≥ 36.67 mg/L for activated sludge microorganisms (OECD 301B)
Key value for chemical safety assessment
Additional information
The toxicity of Oleic acid, monoester with oxybis(propandiol) (CAS 49553-76-6) to microorganisms was investigated in a biodegradation study according to OECD 301B under GLP conditions (Berti, 2012). The study was performed with domestic activated sludge microorganisms. A toxicity control included in the biodegradation study with a test item concentration of 36.67 mg/L reached greater than 25% biodegradation within 14 days (66.8% after 21 d). Thus, the test substance is not inhibitory to microorganisms. According to ECHA Guidance R.7b (ECHA, 2012) the test item concentration can be used as NOEC value for the toxicity to activated sludge microorganisms. Thus, a NOEC (21d) of ≥ 36.67 mg/L resulted.
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