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EC number: 218-056-1 | CAS number: 2043-57-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: OECD 105
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- column elution method
Test material
- Reference substance name:
- 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluoro-8-iodooctane
- EC Number:
- 218-056-1
- EC Name:
- 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluoro-8-iodooctane
- Cas Number:
- 2043-57-4
- Molecular formula:
- C8H4F13I
- IUPAC Name:
- 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluoro-8-iodooctane
- Test material form:
- other: liquid at 22°C
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 30.7 µg/L
- Temp.:
- 20 °C
- pH:
- 5.8 - 6.4
Any other information on results incl. tables
8.RESULTS
8.1Measurements Column Elution Method
At the initial flow rate of 35 mL/h, the values given in the following table were measured:
Fraction | Volume of aqueous sample (V1) | pH of aqueous sample | Volume of HX after extraction and concentration (V2) | Amount in HX measured in GC (c2) | Solubility in Water (c1) |
mL | mL | mg/L | mg/L | ||
1 (3h) | 35.03 | 6.1 | 1.65 | 0.800 | 0.0377 |
2 (4h) | 35.17 | 6.0 | 1.64 | 0.721 | 0.0335 |
3 (8h) | 36.24 | 6.2 | 3.06 | 0.432 | 0.0365 |
4 (10h) | 33.70 | 5.9 | 2.98 | 0.486 | 0.0430 |
5 (11h) | 34.44 | 6.0 | 2.74 | 0.373 | 0.0297 |
Average | 0.0361 | ||||
Standard Deviation | 0.0050 |
Concentration in water was calculated using the enrichment factor (volume of solution in hexane dividedby volume of aqueous sample) using the following formula: c1 = c2 x (V2/V1)
The recovery rate was calculated at more than 80% and do not take in account in these calculations.
According to the OECD guidelines, the concentrations of at least five fractions should be constant within ± 30% to determine the solubility of the substance.
In the case of the perfluorohexylethyliodide with an average solubility of 36.1 µg/L, to satisfy this condition the values of the tables should be in a range of 36.1± 10.8 µg/L, so between 25.3 µg/L and 46.9 µg/L; this was actually the case.
At a flow rate of 17.5 mL/h, half of the initial flow rate, the values given in the following table were measured:
Fraction | Volume of aqueous sample (V1) | pH of aqueous sample | Volume of HX after extraction and concentration (V2) | Amount in HX measured in GC (c2) | Solubility in Water (c1) |
mL | mL | mg/L | mg/L | ||
1 (3h) | 16.97 | 6.0 | 0.73 | 0.710 | 0.0304 |
2 (4h) | 21.19 | 5.9 | 0.74 | 0.660 | 0.0231 |
3 (6h) | 19.19 | 6.1 | 1.03 | 0.450 | 0.0242 |
4 (7h) | 16.14 | 6.0 | 0.74 | 0.530 | 0.0244 |
5 (8h) | 15.86 | 5.8 | 1.20 | 0.330 | 0.0249 |
Average | 0.0254 | ||||
Standard Deviation | 0.0029 |
To satisfy the OECD condition, the values of the tables should be in a range of 25.4± 7.62 µg/L, so between 33.0 µg/L and 17.8 µg/L; this was actually the case. Finally, according to the OECD guidelines, the mean values obtained from two tests with different flows should not differ by more than 30%.
In the case of the perfluorohexylethyliodide, the average solubility of the two runs at different flow rateswas30.7 µg/L. To satisfy the 30% of error, the two values should be in the range from 21.5 µg/L to 39.9µg/L; this was also the case.
As all the conditions of the column elution method OECD were satisfied, the water solubility of theperfluorohexylethyliodide was defined as 30.7± 9.21 µg/L.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
In conclusion of this report, according to the OECD guideline 105, the following data for the perfluorohexylethyliodide was found: Water solubility= 30.7± 9.21 µg/L
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