Registration Dossier
Registration Dossier
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EC number: 218-491-7 | CAS number: 2163-00-0
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: only orientating information about the inhalation hazard
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 963
- Report date:
- 1963
Materials and methods
- Principles of method if other than guideline:
- according to BASF-internal standard
- GLP compliance:
- no
- Test type:
- other: inhalation hazard test
Test material
- Reference substance name:
- 1,6-dichlorohexane
- EC Number:
- 218-491-7
- EC Name:
- 1,6-dichlorohexane
- Cas Number:
- 2163-00-0
- Molecular formula:
- C6H12Cl2
- IUPAC Name:
- 1,6-dichlorohexane
- Test material form:
- other: liquid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- male/female
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- other: inhalation hazard test
- Details on inhalation exposure:
- Inhalation of an atmosphere saturated with vapour. For saturation, air was conducted through a layer of about 5 cm of the product.
- Duration of exposure:
- 8 h
- No. of animals per sex per dose:
- 12
- Control animals:
- no
Results and discussion
- Mortality:
- none
- Clinical signs:
- other: none
- Other findings:
- Necropsy findings: No abnormalities detected.
Applicant's summary and conclusion
- Conclusions:
- 1,6-Dichlorohexane was tested in 12 animals. The rats were exposed to an atmosphere saturated with vapour for about 8 hours. For saturation, air was conducted through a layer of about 5 cm of the product. No mortality and no clinical signs were observed.
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