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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Surface tension
Administrative data
Link to relevant study record(s)
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 01-06.12.2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 115 (Surface Tension of Aqueous Solutions)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- OECD harmonised ring method
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: RÜTGERS Germany GmbH, Varziner Strasse 49, 47138 Duisburg (Germany)
- Lot/Batch n°: Lab Sample 18.9.2017
- Expiration date of the lot/batch: 31-12-2018
- Purity test date: 18-09-2017 - Key result
- Surface tension:
- 48.45 mN/m
- Temp.:
- 20 °C
- Conc.:
- 90 other: % saturated solution
- Conclusions:
- The surface tension of a 90% saturated aqueous solution of the test item 4-(1-phenylethyl)phenol was determined to be 48.45 mN/m (SD +/- 0.05 mN/m) at 20°C.
- Executive summary:
The test was performed to determine the surface tension of an aqueous solution with a concentration of 90% of the saturation concentration of the test item 4-(1-phenylethyl)phenol via tensiometer using the OECD-harmonised ring method. The study was performed according to OECD TG 115, EU Method A.5 and in compliance to GLP.
The density of the test solution was determined in a preliminary measurement via the buoyancy method to be 1.004 g/cm3 (20.0°C).
The temperature of the test solution during the whole series of measurements was between 19.9 and 20.0°C, and the validity criteria for the test were fulfilled.
The determination was carried out with a tensiometer in ten successive measurements (SD ≤ 0.05 mN/m).
The surface tension of a 90% saturated aqueous solution of the test item was determined to be 48.45 mN/m (SD +/- 0.05 mN/m) at 20°C.
Considering that distilled water has a surface tension of 72.75 mN/m at 20°C and the test item showed a surface tension below 60 mN/m under the conditions of this test method, the test item should be regarded as being surface-active material.
- Endpoint:
- surface tension
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- 1. HYPOTHESIS FOR THE ANALOGUE APPROACH
Approx. 20 % of the target compound, the registration substance phenol, styrenated, accounts for the source substance, 4-styrenated derivative of phenol, 4-(1-phenylethyl)phenol, and thus is assumed to represent the low-molecular fraction in the target mixture, that may have some amphiphilic properties. Its stretched chemical structure suggests that it will have the highest surface activity - if at all - of the monostyrenated phenol fraction.
Surface activity is not considered relevant for the target compound, however was meant to be a pre-exercise for the determination of the log Pow.
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
not relevant (see 1. above)
The source compound is a position-isomer of monostyrenated phenol with the substituent, 1-phenylethyl or α-monomethylbenzyl, in the para-position of the central phenol ring. In the target substance, the registration substance phenol, styrenated, the isomer is present at a substantial amount of about 35 to 55 %, in total approx. 50 to 70 % including the 2-styrenated isomer with about 10 to 25 %. The remainder of the target compound is represented by the di-tyrenated phenol, 2,4-(1-phenylethyl-)phenol, with about 20 to 40 %, and tri-styrenated phenol, 2,4,6-(1-phenylethyl-)phenol, with a minor amount of about 0.2 to 5 %.
3. ANALOGUE APPROACH JUSTIFICATION
not relevant (see 1.above) - Reason / purpose for cross-reference:
- read-across source
- Principles of method if other than guideline:
- Read-across to preceding entry:
Source test material: 4-(1-phenylethyl)phenol;
Reference: Thieu 2018 - Key result
- Surface tension:
- 48.45 mN/m
- Temp.:
- 20 °C
- Conc.:
- 90 other: % saturated solution
Referenceopen allclose all
Determination of the density
The buoyancy method yielded a density of the test solution of 1.004 g/cm3 at 20.0°C. The density was used for the correction method of Harkins and Jordan in the determination of the surface tension.
Temperature
The temperature of the test solution during the whole series of measurements was between 19.9 and 20.0°C.
Time line of the surface tension determination
Start of measurement was 27.1 minutes after transfer of the test solution into the vessel. After that time, 15.2 minutes were needed to reach equilibrium at which 10 successive measurements were successfully achieved with a standard deviation of <= 0.05 mN/m.
Surface tension of the test item
Measurement No. 1) | Time 2) (min) | Time 3) (min) | Surface Tension (mN/m) | Temperature (°C) |
1 | 36.13 | 9.01 | 48.39 | 20.0 |
2 | 36.83 | 9.71 | 48.41 | 20.0 |
3 | 37.54 | 10.42 | 48.41 | 20.0 |
4 | 38.25 | 11.13 | 48.44 | 20.0 |
5 | 38.96 | 11.84 | 48.44 | 20.0 |
6 | 39.65 | 12.53 | 48.44 | 20.0 |
7 | 40.33 | 13.21 | 48.49 | 20.0 |
8 | 40.98 | 13.86 | 48.50 | 20.0 |
9 | 41.75 | 14.64 | 48.51 | 20.0 |
10 | 42.41 | 15.29 | 48.52 | 20.0 |
Mean | - | - | 48.45 | 20.0 |
SD (+/-) | - | - | 0.05 | 0.0 |
SD = standard deviation
1) of the last 10 measurements
2) Time from transfer of the test solution into test vessel until end of each measurement
3) Time start of measurement until end of each measurement
Description of key information
The surface tension of 4-(1-phenylethyl)phenol (4 -MSP) was determined by means of a tensiometer using the OECD-harmonized ring method in accordance with OECD Guidance 115 and EU method A.5.
The surface tension of a 90 % saturated aqueous solution of the test item was determined to be 48.45 mN/m (SD ± 0.05 mN/m) at 20°C. As the surface tension value is below the threshold of 60 mN/m under the conditions of this test method, the test item should be regarded as having some surface active potential.
Key value for chemical safety assessment
- Surface tension:
- 48.45
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.