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EC number: 689-188-9 | CAS number: 149343-84-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24 March 1997 to 26 March 1997.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- not specified
- Principles of method if other than guideline:
- The procedure employed is that outlined in the draft "HPLC-screening method for the determination of the adsorption-coefficient on soil-comparison of different stationary phases", W Kordel, J Stutte and G Kotthoff, Fraunhofer - lnstitut fur Umweltchemie und Okotoxikologie.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil
- Specific details on test material used for the study:
- No further details specified in the study report.
- Radiolabelling:
- no
- Test temperature:
- 30 °C
- Details on study design: HPLC method:
- Dead time
The dead time was determined by measuring the retention time of a 292 mg/l solution of formamide (purity 99.5%*) in methanol.
The HPLC parameters were as follows:
Column: Hypersil CN – BDS 5μ (250 x 4.6 mm id)
Column temperature: 30 °C
Mobile phase: methanol:water (50:50) *
Flow rate: 1 ml/min
Injection volume: 25 μl
Wavelengths: reference standards and dead time - 210 nm; sample - 343 nm
* pH - 7.40.
Calculation
The capacity factor (k) is calculated using equation:
k = (tR – t0) / t0
where:
tR = retention time of the substance (mins)
t0 = dead time (mins) - Key result
- Type:
- Koc
- Value:
- < 21.4 dimensionless
- pH:
- 7.4
- Temp.:
- 30 °C
- Matrix:
- Soil
- Remarks on result:
- other: % Org. carbon not specified
- Key result
- Type:
- log Koc
- Value:
- < 1.33 dimensionless
- pH:
- 7.4
- Temp.:
- 30 °C
- Matrix:
- Soil
- Remarks on result:
- other: % Org. carbon not specified in the study report.
- Details on results (HPLC method):
- Under the conditions of the test, the test material showed negligible retention on the HPLC column. The log10 Koc was deduced by direct comparison of the sample retention time with that of the reference standard having the lowest log10 K0c value.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The soil adsorption coefficient has been determined to be less than 21.4, log10 Koc < 1.33, using an HPLC screening method.
- Executive summary:
DETERMINATION OF SOIL ADSORPTION COEFFICIENT
The soil adsorption coefficient of JPR Blue 100 has been determined to be less than 21.4, log10 Koc < 1.33, using an HPLC screening method.
Reference
Dead time
The retention time determined for formamide in shown below:
Injection |
Retention time (mins) |
1 2 |
3.418 3.418 |
Mean |
3.418 |
Calibration
The retention times obtained for the calibration standards are shown below:
Standard |
Retention time (mins) |
||
Injection 1 |
Injection 2 |
Mean |
|
N-methylbenzamide Benzamide 2-nitrobenzamide 2-chlorobenzamide Simazine |
3.867 3.769 3.779 3.794 4.419 |
3.869 3.768 3.779 3.798 4.418 |
3.868 3.769 3.779 3.796 4.419 |
SOIL ADSORPTION COEFFICIENT
The capacity factors (k) for the reference standards were determined from the mean retention times. The capacity factors are shown below together with the literature values for log10 Koc:
Standard |
Capacity factor k |
Log10 k |
Log10 Koc |
N-methylbenzamide Benzamide 2-nitrobenzamide 2-chlorobenzamide Simazine |
0.132 0.103 0.106 0.111 0.293 |
-0.881 -0.989 -0.976 -0.956 -0.534 |
1.33 1.34 1.44 1.47 1.77 |
Sample
The retention times of the test material are shown below:
Injection |
Retention time (mins) |
Capacity factor k |
Log10 k |
Log10 Koc |
Mean Log10 Koc |
Koc |
1 2 |
1.932 1.935 |
-0.435 -0.434 |
N/A* N/A* |
<1.33ꝉ <1.33ꝉ |
<1.33 |
<21.4 |
Log10 Koc: <1.33
Koc: <21.4
* logarithmic values do not exist for negative numbers.
ꝉ determined with reference to the log10 Koc and retention time data shown in tables above.
Description of key information
The soil adsorption coefficient has been determined to be less than 21.4, log10 Koc < 1.33.
Key value for chemical safety assessment
- Koc at 20 °C:
- 21.4
Additional information
The soil adsorption coefficient has been determined to be less than 21.4, log10 Koc < 1.33, using an HPLC screening method.
[LogKoc: 1.33]
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