Reaction mass of 7,7-dimethyl-2-methylidenebicyclo[2.2.1]heptane and (1R)-2,2-dimethyl-3-methylenebicyclo[2.2.1]heptane and (1S)-2,2-dimethyl-3-methylenebicyclo[2.2.1]heptane and (1S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene

Hydrolysis

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

hydrolysis

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Justification for type of information:

JUSTIFICATION FOR DATA WAIVING
The substance is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions.

Reason / purpose for cross-reference:

data waiving: supporting information

Reason / purpose for cross-reference:

data waiving: supporting information

Reason / purpose for cross-reference:

data waiving: supporting information

Reason / purpose for cross-reference:

data waiving: supporting information

Reference 2

Endpoint:

hydrolysis

Type of information:

other: data from peer review handbook

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Qualifier:

no guideline required

Principles of method if other than guideline:

Estimation of resistance to hydrolysis based on organic functional groups present in the molecule

Estimation method (if used):

Estimation of resistance to hydrolysis based on organic functional groups present in the molecule

Test performance:

No test performed.

The test material is not expected to undergo hydrolysis in the environment due to the presence of the alkene functional group that is considered to be resistant to hydrolysis and also the lack of functional groups that hydrolyze under environmental conditions.

Validity criteria fulfilled:

not applicable

Conclusions:

The test item is not expected to undergo hydrolysis in the environment.

Executive summary:

According to the peer reviewed handbook, the test item is not expected to undergo hydrolysis in the environment due to the presence of resistant to hydrolysis alkene functional group and the lack of other groups that hydrolyze under environmental conditions.

Reference 3

Endpoint:

hydrolysis

Type of information:

other: data from peer review handbook

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Qualifier:

no guideline required

Principles of method if other than guideline:

Estimation of resistance to hydrolysis based on organic functional groups present in the molecule

Estimation method (if used):

Estimation of resistance to hydrolysis based on organic functional groups present in the molecule

Test performance:

No test performed.

The test material is not expected to undergo hydrolysis in the environment due to the presence of the alkene functional group that is considered to be resistant to hydrolysis and also the lack of functional groups that hydrolyze under environmental conditions.

Validity criteria fulfilled:

not applicable

Conclusions:

The test item is not expected to undergo hydrolysis in the environment.

Executive summary:

According to the peer reviewed handbook, the test item is not expected to undergo hydrolysis in the environment due to the presence of resistant to hydrolysis alkene functional group and the lack of other groups that hydrolyze under environmental conditions.

Reference 4

Endpoint:

hydrolysis

Type of information:

other: data from peer review handbook

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Qualifier:

no guideline required

Principles of method if other than guideline:

Estimation of resistance to hydrolysis based on organic functional groups present in the molecule

Estimation method (if used):

Estimation of resistance to hydrolysis based on organic functional groups present in the molecule

Test performance:

No test performed.

The test material is not expected to undergo hydrolysis in the environment due to the presence of the alkene functional group that is considered to be resistant to hydrolysis and also the lack of functional groups that hydrolyze under environmental conditions.

Validity criteria fulfilled:

not applicable

Conclusions:

The test item is not expected to undergo hydrolysis in the environment.

Executive summary:

According to the peer reviewed handbook, the test item is not expected to undergo hydrolysis in the environment due to the presence of resistant to hydrolysis alkene functional group and the lack of other groups that hydrolyze under environmental conditions.

Reference 5

Endpoint:

hydrolysis

Type of information:

other: data from peer review handbook

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Qualifier:

no guideline required

Principles of method if other than guideline:

Estimation of resistance to hydrolysis based on organic functional groups present in the molecule

Estimation method (if used):

Estimation of resistance to hydrolysis based on organic functional groups present in the molecule

Test performance:

No test performed.

The test material is not expected to undergo hydrolysis in the environment due to the presence of the alkene functional group that is considered to be resistant to hydrolysis and also the lack of functional groups that hydrolyze under environmental conditions.

Validity criteria fulfilled:

not applicable

Conclusions:

The test item is not expected to undergo hydrolysis in the environment.

Executive summary:

According to the peer reviewed handbook, the test item is not expected to undergo hydrolysis in the environment due to the presence of resistant to hydrolysis alkene functional group and the lack of other groups that hydrolyze under environmental conditions.

Description of key information

Data waiving (study scientifically not necessary): The study does not need to be conducted because the substance is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions.

Supporting study: L-camphene, D-camphene, fenchene and L-alpha pinene: Based on the functional groups of the main components, the test substance is not expected to undergo hydrolysis in the environment.

Additional information

Data waiving (study scientifically not necessary): The study does not need to be conducted because the substance is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions.

Supporting study: L-camphene, D-camphene, fenchene and L-alpha pinene: The main components of the multi-constituent test substance have in common the presense of the alkene functional group. According to the peer reviewed handbook, the alkene functional group is considered to be resistant to hydrolysis and also, none of these main components has any other related functional group potentially susceptible to hydrolysis. Thus, the test substante is considered as resistant to undergo hydrolysis in the environment.