Registration Dossier
Registration Dossier
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EC number: 200-370-5 | CAS number: 58-22-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Testosterone is very toxic to aquatic algae according to the EU chemical classification for aquatic toxicity, since the EC50 is below 1 mg/L.
Key value for chemical safety assessment
Additional information
A study is available on the effect of the test compound testosterone on the growth of the green algae Desmodesmus subspicatus.
The study was conducted in agreement with te test guideline OECD 201, and the EC guideline Part 2 - Testing Methods, Part C.3.
Testosterone produced an inhibition effect on the growth of Desmodesmus subspicatus at all concentrations. The EbC50 (biomass) was 0.5 mg/L, the ErC50 (growth rate) was 0.7 mg/L. At the highest concentration (saturated solution), testosterone is algicidal.
Therefore, testosterone is very toxic to Desmodesmus subspicatus, according to the EU chemical classification for aquatic toxicity, since the EC50 is below 1 mg/L. Since at the highest concentration the fluorescence was lower at the start of the test, it can be concluded that the saturated solution of testosterone has a algicidal effect.
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