Registration Dossier
Registration Dossier
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EC number: 277-923-2 | CAS number: 74563-64-7
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Phytantriol is bioavailable after oral exposure. It has a tmax > 3h, accumulates in the body and can be found in plasma in a dose-dependent concentration.
Experimental data show that Phytantriol in three different formulations penetrates the intact pig skin. The penetration of the test article through the pig skin from the 3 tested formulations was maximum 5.5%.
Metabolism of Phytantriol will lead to substances that are of higher water solubility than Phytantriol itself, which facilitates its excretion.
Key value for chemical safety assessment
- Bioaccumulation potential:
- high bioaccumulation potential
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
