Registration Dossier
Registration Dossier
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EC number: 423-630-1 | CAS number: 62435-71-6
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The work described was performed in compliance with UK GLP standards (Schedule 1, Good Laboratory Practice Regulations 1997 (SI 1997/654)). These Regulations are in accordance with GLP standards published as OECD Principles on Good Laboratory Practice (revised 1997, ENV/MC/CHEM(98)17); and are in accordance with, and implement, the requirements of Directives 87/18/EEC and 88/320/EEC.
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.1 (Acute Toxicity for Fish)
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- no
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Test type:
- semi-static
- Water media type:
- not specified
- Total exposure duration:
- 96 h
- Hardness:
- Total hardness of approximately 100 mg/l as CaCO3.
- Duration:
- 3 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Duration:
- 6 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Results with reference substance (positive control):
-LC50: 96-Hour LC50 of greater than 100mg/l. Correspondingly the No Observed Effect Concentration was equal to 100 mg/l.- Validity criteria fulfilled:
- yes
- Conclusions:
- No Observed effect concentration after 96h 100mg/L
- Executive summary:
No Observed effect concentration after 96h 100mg/L
Reference
Description of key information
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
- Mortality:No mortalities in 20 fish exposed to a test concentration of 100 mg/l for a period of 96 hours.
- LC50: 96-Hour LC50 of greater than 100mg/l. Correspondingly the No Observed Effect Concentration was equal to 100 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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