Registration Dossier
Registration Dossier
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EC number: 222-222-9 | CAS number: 3390-61-2
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC25and EC50(28-day) >100 mg/kg dwt (nominal), nitrate formation rate, soil microorganisms, based on read-across within the Reconsile Siloxane Category.
These values are equivalent to >400 mg/kg dwt when normalised to 2% organic carbon.
Key value for chemical safety assessment
Additional information
No data are available with 1,3,5-trimethyl-1,1,3,5,5-pentaphenyltrisiloxane (CAS 3390-61-2). Data from the structural analogue, phenyl silsesquioxanes (EC 939-487-8), are read across.
28-day EC25and EC50values of >100 mg/kg dwt were reported for the effects on the nitrate formation rate of soil microorganisms, based on nominal concentrations. Nitrate formation rates were significantly reduced in all treatment groups compared to the control, which gives a 28-day LOEC of 1.2 mg/kg dwt. However, a dose response relationship was not observed, suggesting the effects to be due to a non-toxic mechanism. The EC25, EC50and LOEC values are equivalent to >400, >400 and 4.8 mg/kg dwt when normalised to 2% organic carbon.
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