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EC number: 222-222-9 | CAS number: 3390-61-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Biodegradation in water: screening tests: 2.2% in 28 days (O2 consumption, OECD 301F), based on read-across from a structurally-related substance.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
There are no reliable ready biodegradation data available for 1,3,5-trimethyl-1,1,3,5,5-pentaphenyltrisiloxane (CAS 3390-61-2), therefore good quality data for the structurally-related substance, 3-[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-3-phenyl-1,5-divinyltrisiloxane (CAS No. 60111-47-9), have been read across.
1,3,5-trimethyl-1,1,3,5,5-pentaphenyltrisiloxane (CAS 3390-61-2) and 3-[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-3-phenyl-1,5-divinyltrisiloxane (CAS No. 60111-47-9) are structurally-similar substances, both are siloxanes with phenyl functionality. The target substance 1,3,5-trimethyl-1,1,3,5,5-pentaphenyltrisiloxane (CAS 3390-61-2) is a linear siloxane containing three Si atoms linked by oxygen. The terminal silicon atoms are each substituted with one methyl group and two phenyl groups, and the central silicon atom is substituted with one methyl and one phenyl group. The source substance 3-[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-3-phenyl-1,5-divinyltrisiloxane (CAS No. 60111-47-9) is a branched structure of four Si atoms,the longest siloxane chain contains three silicon atoms and two oxygen atoms, with a Si-O branch on the central silicon atom in the chain. The terminal silicon atoms are each substituted with two methyl and one vinyl group, whilst the central silicon atom has one phenyl group attached.
1,3,5-trimethyl-1,1,3,5,5-pentaphenyltrisiloxane (CAS 3390-61-2) and 3-[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-3-phenyl-1,5-divinyltrisiloxane (CAS No. 60111-47-9) are within the Siloxane Category of substances within which, in general, there is no evidence of any significant biodegradation.
The table below presents ready biodegradation data for substances within the Siloxane Category.
It is therefore considered valid to read-across the results for 3-[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-3-phenyl-1,5-divinyltrisiloxane (CAS No. 60111-47-9)
to fill the data gap for the registered substance. Additional information is given in a supporting report (PFA, 2014i) attached in Section 13.
Table: Ready biodegradation data for substances within the Siloxane Category
CAS |
Name |
Readily biodegradable? Yes/no |
Result: Biodegradation after 28 days (%) |
Guideline |
Test type |
Reliability |
107-46-0 |
Hexamethyldisiloxane |
No |
2% |
OECD 301C |
BOD |
1c |
107-51-7 |
Octamethyltrisiloxane |
No |
-3.70% |
OECD 310 |
CO2 |
1a |
540-97-6 |
Dodecamethylcyclohexasiloxane |
No |
4.5% |
OECD 310 |
CO2 |
1a |
541-02-6 |
Decamethylcyclopentasiloxane |
No |
0.14% |
OECD 310 |
CO2 |
1a |
541-05-9 |
Hexamethylcyclotrisiloxane |
No |
0.06% |
OECD 310 |
CO2 |
1a |
556-67-2 |
Octamethylcyclotetrasiloxane |
No |
3.70% |
OECD 310 |
CO2 |
1a |
1873-88-7 |
1,1,1,3,5,5,5-heptamethyltrisiloxane |
No |
0% |
OECD 310/ ISO Guideline No 14593 |
CO2 |
1a |
2627-95-4 |
1,1,3,3-tetramethyl-1,3-divinyldisiloxane |
No |
0% |
OECD 301D |
BOD |
1a |
17928-28-8 |
1,1,1,3,5,5,5-heptamethyl- 3-[(trimethylsilyl)oxy] trisiloxane |
No |
0% |
OECD 301F |
BOD |
1a |
17955-88-3 |
1,1,1,3,5,5,5-heptamethyl-3-octyltrisiloxane |
No |
10 – 32 % after 25 d |
OECD 301B |
CO2 |
1a |
60111-47-9 |
3-[(dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-3-phenyl-1,5-divinyltrisiloxane |
No |
2.20% |
OECD 301F |
BOD |
1a |
69304-37-6 |
1,3-dichloro-1,1,3,3-tetraisopropyldisiloxane |
No |
0% (BOD); 100% (GC) |
OECD 301C |
BOD |
1a |
70940-00-0 |
1,1,7,7,-Tetramethyl-3,3,5,5,-Tetraphenyl-Tetrasiloxane |
No |
9.7 and 9.9% |
OECD 301B |
CO2 |
1a |
180073-46-5 |
Pentasiloxane, 1,1,9,9-tetramethyl-3,3,5,5,7,7-hexaphenyl- |
No |
5.2 and 4.4% |
OECD 301B |
CO2 |
1a |
352230-22-9 |
Siloxanes and Silicones, di-Ph, Ph (trimethylsilyl)oxy |
No |
0% |
OECD 301F |
BOD |
1a |
3-[(Dimethylvinylsilyl)oxy]-1,1,5,5-tetramethyl-3-phenyl-1,5-divinyltrisiloxane attained 2.2% biodegradation in 28 days (O2 consumption).
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