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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Justification for type of information:
refer to analogue justification provided in IUCLID section 13
Cross-reference
Reason / purpose for cross-reference:
read-across source
Reference
Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
other: case report, poisoning
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: case report
Study type:
poisoning incident
Endpoint addressed:
acute toxicity: oral
GLP compliance:
no
Type of population:
general
Subjects:
- Number of subjects exposed: 1
- Sex: female
- Age: 26 years old
- Race: Japanese
Ethical approval:
no
Route of exposure:
oral
Details on exposure:
The 26-year old woman took 30 g of oxalic acid. 10 hours after hospitalisation, the patient died.
Clinical signs:
The patient complained about a burning sensation in the throat, dizziness, diarrhoea and cold sweat as well as shock symptom (no further details were given in the report).
Results of examinations:
- Other: Following examination, corrosion of the tongue, inflammation of the esophagus, atony and inflammation of the stomach, and black digested material in stomach and small intestine was observed.
Outcome of incidence:
The patient died.

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Dipotassium oxalate
EC Number:
209-506-8
EC Name:
Dipotassium oxalate
Cas Number:
583-52-8
Molecular formula:
C2K2O4
IUPAC Name:
dipotassium oxalate
Test material form:
solid

Results and discussion

Clinical signs:
Source, Umezum, 1980: The 26-year old woman took 30 g of oxalic acid. 10 hours after hospitalisation, the patient died.

Applicant's summary and conclusion