Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- GLP compliance:
- yes
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- yes
- Total exposure duration:
- 14 d
- Details on test conditions:
- Soil characteristics (e.g. pH, % organic matter):
70% quartz sand, 20% Kaolinite clay, 10% Spagnum moss peat - Nominal and measured concentrations:
- Nominal: 1000 kg/mg soil
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 other: mg/kg soil
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 000 other: mg/kg soil
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Conclusions:
- The 14-Day LC50 (mortality) for the test material to earthworms (Eisenia foetida) based on nominal test concentrations was greater than 1000 mg/kg soil. The No Observed Effect Concentration was 1000 mg/kg soil.
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: read across to K1 study
- Reason / purpose for cross-reference:
- read-across source
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- yes
- Total exposure duration:
- 14 d
- Details on test conditions:
- Soil characteristics (e.g. pH, % organic matter):
70% quartz sand, 20% Kaolinite clay, 10% Spagnum moss peat - Nominal and measured concentrations:
- Nominal: 1000 kg/mg soil
- Key result
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 other: mg/kg soil
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Key result
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 000 other: mg/kg soil
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Conclusions:
- The 14-Day LC50 (mortality) for the test material to earthworms (Eisenia foetida) based on nominal test concentrations was greater than 1000 mg/kg soil. The No Observed Effect Concentration was 1000 mg/kg soil.
Referenceopen allclose all
Description of key information
The 14-Day LC50 (mortality) for the test material to earthworms (Eisenia foetida) based on nominal test concentrations was greater than 1000 mg/kg soil. The No Observed Effect Concentration was 1000 mg/kg soil.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 1 000 mg/kg soil dw
Additional information
According to OECD Guidelines for the Testing of Chemicals, No. 207 Earthworm, Acute Toxicity Test, the acute toxicity of the test substance to earthworms (Eisenia foetida) was determined in a 14 day test.
The test was conducted as a limit test with a nominal concentration of 1000 mg/kg soil.
The 14-Day LC50 (mortality) for the test material to earthworms (Eisenia foetida) based on nominal test concentrations was greater than 1000 mg/kg soil. The No Observed Effect Concentration was 1000 mg/kg soil.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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