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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
09 Mar 2000 - 16 Mar 2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 8135C// 951020
- Expiration: 17 Feb 2001
- Purity: 100%
- Storage: at room temperature in the dark
- Physical Appearance: red powder
Key result
Water solubility:
< 1 mg/L
Conc. based on:
test mat.
Temp.:
20.5 °C
pH:
7.1
Conclusions:
Solubility of the test item was found to be < 1.0 mg/L at 20.5 ±0.5 °C.
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
14 Apr 2014
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Qualifier:
no guideline followed
Principles of method if other than guideline:
- Principle of test: Water solubility is determined visually.
- Method: Prepare sample solutions of 1 and 10mg sample / liter water in volumetric flaks with stoppers. Add a magnetic stirring element to both volumetric flasks. Place both flasks under stirring in a temperature controlled heating obth at 30°C for at least 72h. After 72h, place both flasks under stirring in a temperature controlled heating bath at 20 ± 0.5°C for at least 24h. Visually verify for undissolved particles.
GLP compliance:
not specified
Type of method:
flask method
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 8135N/ 021340
Key result
Water solubility:
< 1 mg/L
Temp.:
20 °C
pH:
>= 5 - <= 7
Remarks on result:
other:
Remarks:
pH not stated however typically the pH of tap water would be between 5 and 7.
Conclusions:
Solubility of test item was found to be less than 1 mg/L.
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13 February 2017 - 17 February 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
not specified
Qualifier:
equivalent or similar to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
not specified
GLP compliance:
not specified
Type of method:
flask method
Specific details on test material used for the study:
Product code / batch: 8135N / 021340
Key result
Water solubility:
< 0.1 mg/L
Conc. based on:
test mat.
Temp.:
38 °C
pH:
5.5
Remarks on result:
other: Based on the visual observation of the sample solution and filter membrane
Remarks:
pH of blank demineralized water from water purification system (Millipore, MilliQ Integral 15) = 5.75 Maximum temperature recorded before setpoint was changed to 20°C.
Conclusions:
Based on the visual observation of the sample solution and filter membrane, the water solubility of pigment sample 8135N batch 021340 (C.I. Pigment Red 81:5, CAS 63022-06-0)
is determined to be <0.1mg/L. When inspecting the Stericup-GV membrane, pigment particles are clearly visible. The filtrate is clear and not coloured. Photographic evidence is available in an Appendix of the attached report.

Description of key information

In the key study (Cappelle 2017) Water solubility of a C.I. Pigment Red 81 :5 was determined by use of the flask method. The test method was based on regulation (EC) No 440/2008 (test methods pursuant to Regulation (EC) No 1907/2006) section A.6 and OECD guideline 105.

Based on the visual observation of the sample solution and filter membrane, the water solubility of pigment sample 8135N batch 021340 (C.I. Pigment Red 81:5, CAS 63022-06-0) is determined to be <0.1mg/L.

Key value for chemical safety assessment

Water solubility:
0.1 mg/L
at the temperature of:
20 °C

Additional information