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Short-term toxicity to aquatic invertebrates

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Description of key information

The 48-hour NOEC (highest concentration tested without toxic effects after the exposure period of 48 hours), and the 48-hour ECO of FAT 60'253/A to Daphnia magna were determined to be at least 0.010 mg/l (loading rate of 100 mg/l).

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The acute toxicity of the test item FAT 60'253/A to Daphnia magna was determined in a 48-hour static test according to the Commission Directive 92/69/EEC, Part C.2 (1992), and the OECD Guideline for Testing of Chemicals, No. 202, Part I (1984).

A limit test was performed in accordance with the Commission Directive 92/69/EEC to demonstrate that the test item has no toxic effect on the test organisms up to and including the highest test item concentration which can be dissolved or very finely dispersed in test water.

Due to the very low water solubility of the test item, a supersaturated dispersion of the test item with a loading rate of 100 mg/l was continuously stirred at room temperature in the dark over 7 days. Then, the dispersion was filtered. Only the undiluted filtrate with the maximum concentration of dissolved and very finely dispersed test item was used as the test medium. Additionally, a control was tested in parallel.

The analytically determined test item concentration in the test medium were 0.0093 and 0.011 mg/l at the start and the end of the test period, respectively. Under the test conditions, the test item was stable during the test period of 48 hours. All biological results are related to the mean measured test item concentration of 0.010 mg/l, calculated as the average of all measurements.

In the control and in the undiluted filtrate, no immobilized or dead test organisms or other signs of intoxication were determined during the test period of 48 hours.

The 48-hour NOEC (highest concentration tested without toxic effects after the exposure period of 48 hours), and the 48-hour EC0 of FAT 60'253/A to Daphnia magna were determined to be at least 0.010 mg/l (loading rate of 100 mg/l). The 48-hour NOEC and the 48 -hour EC0 might even be higher but concentrations of the test item above the maximum concentration which could be dissolved or very finely dispersed in the test water were not tested, according to the guidelines. The 48-hour EC50 and the 48-hour EC100 were clearly higher than the solubility limit of the test item in the test water. These values could not be quantified, since the test item had no toxic effect on the daphnids at the highest test item concentration which could be dissolved or very finely dispersed in the test water.