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EC number: 204-258-7
CAS number: 118-52-5
Some data regarding short-term
toxicity to invertebrates and to fish are reported in HSDB Report of
1,3-Dichloro-5,5-dimethylhydantoin with reference to USEPA,
Office of Pesticide Programs; Pesticide Ecotoxicity Database (2000) on
1,3-Dichloro-5,5-dimethyl-2,4-imidazolidinedione (118-52-5). No data
are available regarding to aquatic algae and cyanobacteria.
All data are reported in the
specific summary and in this generic summary only the lowest values are
- LC50 Oncorhynchus mykiss (Rainbow
trout, juvenile) 96h= 0.58 ppm equivalent to 0.58 mg/l
- EC50 Daphnia magna 48h = 0.47 ppm
equivalent to 0.47 mg/l
Based on these values of short term
toxicity to invertebrates and to fish the classification H400 (acute
aquatic hazard, cat.1) is proposed for DCDMH according to the CLP
Regulation (EC n.1272/2008).
No data are available regarding
long-term toxicity of 1,3-Dichloro-5,5-dimethylhydantoin.
As reported in the document Halohydantoins
RED, EPA 739-R-07-001, September 2007 generic dihalodialkylhydantoin
has been shown to hydrolyze relatively rapidly (under abiotic conditions
half-lives of less than 30 days in pH 5, pH 7, and pH 9). The major
degradate, dimethylhydantoin (DMH ), was hydrolytically stable but , as
reported always in the document of EPA, DMH demonstrates low toxicity to
terrestrial and aquatic animals (for major details regarding the data
see table p.38 of the document Halohydantoins RED, EPA 739-R-07-001,
Moreover in database ECOTOX-EPA for
the research with CAS 118-52-5 (1,3-dichloro-5,5-dimethylhydantoin) some
long-term aquatic toxicity data for CAS 16079-88-2
(1-bromo-3-chloro-5,5-dimethylhydantoin) were reported. This association
was done by EPA probably due to the similarity of the two substances
(same structure but different halogen in position 1). Based on data
reported in database ECOTOX-EPA with reference to Pesticide
Ecotoxicity Database (1992) for
1-bromo-3-chloro-5,5-dimethylhydantoin NOEC Daphnia magna 21 days = 70.9
mg/l and NOEC Pimephales promelas 33 days= 14 mg/l.
Based on data available for major
metabolite and for a similar substance
(1,3-dichloro-5,5-dimethylhydantoin) no classification for chronic
aquatic toxicity is proposed for DCDMH according to the CLP Regulation
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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