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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

The acute toxicity data available for 1,3-dichloro-5,5-dimethylhydantoin are: LD50 rat oral = 542 mg/kg/bw, LD50 inhalation rat 1h = 20.5 g/m3 and LD50 dermal rabbit > 20000 mg/kg/bw.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
542 mg/kg bw
Quality of whole database:
Data reported by Health Council of the Netherlands in the document "Committee on Updating of Occupational Exposure Limits. 1,3-Dichloro-5,5-dimethylhydantoin, 2000/15OSH/046, 31 October 2002"

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
20 500 mg/m³ air
Quality of whole database:
Data reported by Health Council of the Netherlands in the document "Committee on Updating of Occupational Exposure Limits. 1,3-Dichloro-5,5-dimethylhydantoin, 2000/15OSH/046, 31 October 2002"

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
Value:
20 000 mg/kg bw
Quality of whole database:
Data reported by Health Council of the Netherlands in the document "Committee on Updating of Occupational Exposure Limits. 1,3-Dichloro-5,5-dimethylhydantoin, 2000/15OSH/046, 31 October 2002"

Additional information

Justification for classification or non-classification