3,7-dimethylnon-6-en-1-yn-3-ol

Biodegradation in water: screening tests

Administrative data

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: well documented guideline study

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2000

Report date:

2000

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

3,7-dimethylnon-6-en-1-yn-3-ol

EC Number:

246-061-9

EC Name:

3,7-dimethylnon-6-en-1-yn-3-ol

Cas Number:

24173-47-5

Molecular formula:

C11H18O

IUPAC Name:

3,7-dimethylnon-6-en-1-yn-3-ol

Study design

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge, domestic (adaptation not specified)

Duration of test (contact time):

28 d

Initial test substance concentration

Initial conc.:

100 mg/L

Based on:

test mat.

Results and discussion

% Degradation

Parameter:

% degradation (O2 consumption)

Value:

5

Sampling time:

28 d

Details on results:

-

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Interpretation of results:

under test conditions no biodegradation observed

Conclusions:

Substance is not readily biodegradable

Executive summary:

ETHYLDEHYDROLINALOOL was tested for its ready biodegradability in the closed bottle test at nominal concentrations of 1 mg/l and 3 mg/1. The study procedure was based on EEC directive 92/69, C.4-E, December 1992, and OECD guideline No. 301 D July 17, 1992. The theoretical oxygen consumption (ThO D) of ETHYLDEHYDROLINALOOL (molecular formula: C11H1SO, molecular weight: 166.27 g/mole) was calculated to be 2.89 mg O2 per mg. The ThOD of the positive control sodium acetate was calculated to be 0.78 mg 02/mg. A stock solution of ETHYLDEHYDROLINALOOL was prepared at a nominal concentration of 100 mg/I (a weighed amount of 101.9 mg/l was dissolved in 1 I of mineral medium). The stock solution was stirred for 15 minutes. The stock was a clear and colourless solution. Test solutions were prepared at nominal concentrations of 1 mg/l and 3 mg/l by adding aliquots of 30 ml or 90 ml of the stock solution to a total volume of 3 I mineral medium. The relative biodegradation values calculated from the O2 measurements performed during the test period of 28 days revealed no significant degradation of ETHYLDEHYDROLINALOOL at both concentrations. ETHYLDEHYDROLINALOOL was found to cause inhibiting effects on bacterial respiration during the first 7 days of exposure. During the remaining test period no inhibition was found which shows a recovery of inhibition within 14 days of exposure. Since all acceptability criteria prescribed by the protocol were met, this study was considered to be valid. In conclusion, ETHYLDEHYDROLINALOOL was not readily biodegradable under the conditions in the closed bottle test presently performed.