Registration Dossier
Registration Dossier
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EC number: 208-792-1 | CAS number: 541-73-1
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original reference not translated (Japanese)
Data source
Reference
- Title:
- No information
- Author:
- Mori T 1980. Okayama Igakkai Zasshi 92:1085-1089
Materials and methods
- Principles of method if other than guideline:
- The effect of mono-, di, tri, and tetra-chlorinated benzene on mitochondrial oxidative phosphorylation was determined by in vitro method. Endpoint study record was created to contribute to the overall results.
- GLP compliance:
- no
- Remarks:
- GLP compliance was not mandatory at the time of the study
Test material
- Reference substance name:
- 1,3-dichlorobenzene
- EC Number:
- 208-792-1
- EC Name:
- 1,3-dichlorobenzene
- Cas Number:
- 541-73-1
- Molecular formula:
- C6H4Cl2
- IUPAC Name:
- 1,3-dichlorobenzene
Constituent 1
Results and discussion
Any other information on results incl. tables
Endpoint study record was created to contribute to the overall results.
The respiratory control index decreased with increase in the number of chlorine and with increase in the concentration of chlorinated benzene.
Decrease in respiratory control index was in the order of ortho> meta> para-dichlorobenzenes. There were differences between isomers.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
