Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Hazard for air

Hazard for terrestrial organisms

Hazard for predators

Additional information

Conclusion on classification

A chemical safety assessment and chemical safety report according to Art. 14 REACH is not required for the registration of a substance in tonnage band 1-10 tonnes. Therefore no PNECs have been derived for this substance.

Toxicity to aquatic invertebrates:

The results from a GLP study for short-term toxicity to daphniae reveal that L-phenylalanine does not show aquatic toxicity.

The 48-hour NOEC was determined to be 100 mg test item/L. The 48-hour LOEC was determined to be > 100 mg test item/L and the 48-hour EC50 value was determined to be > 100 mg test item/L.

Toxicity to algae:

The results from a GLP growth inhibition study reveal that L-phenylalanine does not inhibit the growth of algae.

The NOEC-value of the test item for both inhibition of growth rate and inhibition of yield after 72 hours was 100 mg/L. The EC50-values of the test item for both inhibition of growth rate (ErC50) and yield (EyC50) after 72 hours were > 100 mg/L.

The results of the daphnia and algae studies do not trigger classification.

In line with EU-GHS (Regulation 1272/2008), which refer to potential harmonized classification of L-phenylalanine, L-phenylalanine does not fulfil the criteria relating to environmental hazards.